DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8915 and Dqx1

DIOPT Version :9

Sequence 1:	NP_001285369.1	Gene:	CG8915 / 32715	FlyBaseID:	FBgn0030833	Length:	976	Species:	Drosophila melanogaster
Sequence 2:	XP_038964267.1	Gene:	Dqx1 / 680434	RGDID:	1591766	Length:	780	Species:	Rattus norvegicus

Alignment Length:	670	Identity:	174/670 - (25%)
Similarity:	291/670 - (43%)	Gaps:	118/670 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   194 PQSNRNRNIQHERRSLPIYKQRESILNVLQRDQ--VLIIKGATGSGKSTQLPQYILEWA-AEHRA 255
            |.|:....:..:||:|||:..|...|..|:...  |:::.|..|||||||:||:..|:| |....
  Rat    27 PFSSCYYELLEQRRALPIWAARFLFLEHLESSPTGVVLVSGEPGSGKSTQIPQWCAEFALARGFQ 91

  Fly   256 PVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLRALAMDK 320
            ..::.|:||..:||:|::.|::.|.....|..:||:|........||:|........|:.:|..:
  Rat    92 TGQVTVTQPYPLAAMSLASRVADEMDLTLGHEIGYSIPQEDCTGPNTMLRFCWDRLFLQEVASTR 156

  Fly   321 KSFFKNTTHLIIDEAHERDLDTDF---LLLATKL-ELQKNPHLRLVLMSATMDLEALSNYFGGGT 381
            .....:.  |::|||.||.:.:|.   ||..|:| .|..:|.:.:|..||
  Rat   157 GPGAWSV--LVLDEAQERSVASDLLQGLLRDTRLRNLPGDPRVVIVTDSA--------------- 204

  Fly   382 VMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGKETPSELLAAYYGGN-TIVHPD-IDN 444
                                     :.|:.:.|.|.......|.|     .|.| |:.:.| :..
  Rat   205 -------------------------LEPKFQAFWGNSPTVHVPRE-----PGENPTLTYKDTVPA 239

  Fly   445 DLI----VSLLELLLRQGDAGAVIVYLPGYSDMT----------SLLARLESSLPREQITIILLH 495
            ||:    .::|||..|:...|.|:||||...:::          .:|| :...|||    ::.||
  Rat   240 DLVEAACQAVLELCQREEAPGDVLVYLPSEEEISLCCESLSREMGMLA-VPGPLPR----VLPLH 299

  Fly   496 SQVDNSEQRKVFRTYPGVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTW 560
            .....:.|.....|...|| ||:::..:...|.::|.:.:|||:||.....|:..|.|....|..
  Rat   300 PGCGQAIQTVYEDTDVSVR-KIVVTHWLADFSFSLPFIQHVIDSGLELRSVYNPRIRAESQVLRR 363

  Fly   561 ISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNL----YTIPEIMRRTLDEICLLTK---LAAP 618
            ||:..|:.|..||.....|.|.|||..   :.::|    ...|::....|..:.||.|   :|.|
  Rat   364 ISKCQAEARLLRARGFPPGTCLRLYSK---STLDLEAPPLPHPKVCEENLSSLVLLLKRKQIAEP 425

  Fly   619 DKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYSIYL 683
            .:      ...||.|..:|:||:...|..|..||:..:::.||.|::|.||..::.|.|:.|...
  Rat   426 GE------CHFLDRPAPEALMQALEDLDYLAALDDDGDLSDLGIILSEFPLPPELAKALLASCEF 484

  Fly   684 RCLDSMIIIAAYHS-----VRDPFVLNIERGKKSGQ-QISRVLFAGDGMSDSLAVIKLYEEFTNL 742
            .|:|.|:.:||..:     .|.|..        :|: .:.|.|...||  |..::|::||.|...
  Rat   485 NCVDEMLTLAAMLTAAPGFTRPPLC--------AGEAALRRGLEHADG--DHSSLIQVYEAFVQS 539

  Fly   743 KRKDIGDFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLASSFNNDTNM--IRLALTA 805
            ...:  .:|:...:...|:    ..|..||..:..:.:..|....| .:|.::.|.  ::.||.:
  Rat   540 GADE--TWCQARGLSWEAL----CQARKLRAELLELMQRIELPLSL-PAFGSEQNRRDLQKALLS 597

  Fly   806 GLYPKLAYMDRENKNQLVAE 825
            |.:.| |.|.|...::|.::
  Rat   598 GYFLK-AMMRRGLMSKLPSD 616

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064
		DEXDc	214..395	CDD:214692	50/187 (27%)
		DEXDc	226..368	CDD:238005	47/148 (32%)
		HELICc	479..575	CDD:197757	28/95 (29%)
		HA2	648..733	CDD:214852	25/90 (28%)
		OB_NTP_bind	783..884	CDD:285018	12/45 (27%)
Dqx1	XP_038964267.1	HrpA	15..>601	CDD:224557	169/652 (26%)
Dqx1	XP_038964267.1	OB_NTP_bind	662..737	CDD:400182
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900