Protein Alignment CG8915 and dhx34

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_001121805.1
• Gene: dhx34 / 555838
• ZFINID: ZDB-GENE-061207-30
• Length: 1150
• Species: Danio rerio
• Alignment Length: 1062
• Identity: 269/1062 - (25%)
• Similarity: 439/1062 - (41%)
• Gaps: 278/1062 - (26%)

  Fly    65 DEKMLRQLVDDFL-----------------QSCEPEKQLPGLTKAQRSHVHRLAQHRGLKTVSKG 112
            ||...||  .|::                 ||.:.:|::.. :|:.|...| :|...|     |.
Zfish    23 DEVFFRQ--HDYIQAGSAEHKEFWSFFERFQSFKAKKEMTA-SKSSRQEKH-VALREG-----KA 78

  Fly   113 PEENRVLFISRPQSDGQQQYILCNTKLDICPPLLDVLGQMAGNVERRLMNS------VGDLKCNK 171
            .::...:.:..|: |...:|   ...:.:|.  .|:..::||:..||..:|      :.|.:...
Zfish    79 KKKTGCVDLGLPK-DYDARY---RINISVCS--RDIEERLAGSDHRRRESSGPGRQEITDGRLAL 137

  Fly   172 QQYKDIRLPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGS 236
            ..:.|.....:|..:.:             ::.|::||||::.|:.|:.:::...|:::.|.||.
Zfish   138 LHFLDFNQKQSFSKLSK-------------LRREQKSLPIFQYRDKIVELVRTHPVVVVAGDTGC 189

  Fly   237 GKSTQLPQYILEWAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSN 301
            |||||:|||:|.....:     |..:||||||.||:::|:|.|.....|:.|||.||.....:..
Zfish   190 GKSTQVPQYLLASGINN-----IACTQPRRIACISLAKRVSFESLNQYGSKVGYQIRFETSRTLA 249

  Fly   302 TVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFLLLATKLELQKNPHLRLVLMSA 366
            |.|:..|.|.|||.:..|  :.......||:||.|||.|..||||...:..|...|.||||||||
Zfish   250 TKLLFLTEGLLLRQIQQD--ASLGQYQVLIVDEVHERHLHCDFLLGVLRSLLSLRPDLRLVLMSA 312

  Fly   367 TMDLEALSNYFGGGTVMDVEGRSFEVSIYHL----EDILSKTGYMHPRMEKFLGKPTGKETPSEL 427
            |::::..|:||....|:.|.||.|.:.:.:.    |:.:|::..:.||....:.:...:..|.|
Zfish   313 TINIKLFSSYFNDAPVLQVPGRLFPIQVIYQPIPPEEQVSRSEKLDPRPYLRVLQGIDQRYPQE- 376

  Fly   428 LAAYYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLPREQITII 492
                                           :.|.::::|.|.::::::....::.....|..|:
Zfish   377 -------------------------------ERGDLLLFLSGVAEISTIQEACQTYATHTQRWIV 410

  Fly   493 L-LHSQVDNSEQRKVFR-TYPGVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQ 555
            | |||.:..::|.|||. ..|||| |.|:||||.:||:||..:.:|:|:|..|..::|......:
Zfish   411 LPLHSTLSLAQQDKVFDIAPPGVR-KCIISTNIAETSVTIDGVRFVVDSGKVKEMSFDPKAKMQR 474

  Fly   556 LTLTWISQADAKQRAGRAGRVCHGNCYRLYDNDRMARMNLYTIPEIMRRTLDEICLLTK-LAAPD 619
            |...|||:|.::||.|||||...|.|||||..........|.:|||.|..||.:.|..| :...|
Zfish   475 LQEFWISRASSEQRKGRAGRTGPGVCYRLYSESDYDAFAPYPVPEIHRVALDSLILQMKSMGLGD 539

  Fly   620 KKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLVYSIYLR 684
            .:...|    :|.||..::..:.:.|:..|.|||..|:|.:|.::|:||:.|.|||.||......
Zfish   540 PRTFTF----IDPPPASSIQTAVTYLREQGALDEHGELTSIGRLLAQLPVDVVIGKMLVLGSVFN 600

  Fly   685 CLDSMIIIAAYHSVRDPFV---------------LNIERG------------------KKSGQQI 716
            .::.::.:||..||:.||:               ||...|                  :.||
Zfish   601 LVEPVLTVAAALSVQSPFLRSAQHNPDCSTARQPLNSNHGDPFTLMNTFNAWVQVKADRGSG--- 662

  Fly   717 SRVLFAGDGMSDSLAVIKLYEEFTNLKRK-------------DIG-------------DFCERNF 755
            ||......|:.:.    :|| |..||:|:             |.|             .|.||..
Zfish   663 SRKWCRRRGLEEQ----RLY-EMVNLRRQFKELLRSHGLLEDDTGRATEPQDRARRRERFTERQK 722

  Fly   756 I-------------------CRNAMEMFVSAAS---------------------------TLRDT 774
            :                   ....:|...|:.|                           .||..
Zfish   723 LHQLKRDHELQENTKRKVLRLEEGLEGDASSGSDAEESSTSRKKRKDGAEQTMDIQEVKFKLRHN 787

  Fly   775 VYRIFRFSEASARLASSFNNDTNMIRLALTAGLYPKLAYMDRENKNQLVAEGDPLVQVSRSSCLR 839
            |..:...:.|||.|:|.   ...:::|.|..||||:||..|..|..:..::     ||..:
Zfish   788 VNELQESAYASAALSSL---QQALLKLLLCRGLYPQLAIPDEHNATRKDSD-----QVFHT---- 840

  Fly   840 GKKKQ-------KDLASE-WILFVEKTRTADQISSLEHTTLVSGLMVALAGGKRFIT-------- 888
             :.||       ...||: .:|.|.:..|::...|..|..|  ..:..|...|.:::
Zfish   841 -RNKQGVVIHPTSVFASDPEVLHVPEHETSEFGQSNRHQLL--AFVTLLETNKPYLSNCVRVPAL 902

  Fly   889 ----------EAHGSEMLLCLDSWIRLKCPAEFGLQLHKVRMLTDREFAKLVATRKLSLMSDFIG 943
                      .::.....|.:|.|:.|.              |||.:.|..|.:..|||.:::
Zfish   903 QALLLVANSVNSNADCTRLVVDGWLELS--------------LTDGDAALKVLSSALSLRAEW-- 951

  Fly   944 PETVRRLLEADV--PSTCLAEG 963
                .|||:|.:  ..:|.:.|
Zfish   952 ----ERLLQAQLRQSGSCSSAG 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	12/72 (17%)
		HrpA	208..>702	CDD:441249	167/500 (33%)
		OB_NTP_bind	799..884	CDD:400182	23/92 (25%)
dhx34	NP_001121805.1	HrpA	161..>622	CDD:441249	169/504 (34%)
		OB_NTP_bind	814..910	CDD:400182	22/107 (21%)