Protein Alignment CG8915 and kz

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_476591.1
• Gene: kz / 31205
• FlyBaseID: FBgn0001330
• Length: 1192
• Species: Drosophila melanogaster
• Alignment Length: 1169
• Identity: 258/1169 - (22%)
• Similarity: 443/1169 - (37%)
• Gaps: 346/1169 - (29%)

  Fly     9 KRGRRQ--GRKKAQPMPEQ---------AVVLVVNGRVTGGPKGTGKQKTRPGK--NAKADAG-- 58
            |.||.|  |...|..:||:         .|..|...|:....:...|:|.|..:  ..|:.|.
  Fly    87 KEGRAQLLGDLAAVQIPEEELQQYTSISQVQTVGLKRLPTLDEYLAKKKERQAQVLAEKSSASGL 151

  Fly    59 --DKLKSEDEKMLRQLVDDFLQSCEPEKQLPGLTKAQRSHVHRLAQHRGLKTVSKGPEENRVLFI 121
              :.:|....|:|          .|.|::|    :|:|.:.:.::.....:..|...|::.
  Fly   152 RVNAIKGSKRKLL----------VEEEEEL----QAKRKNPNVISVEEDDEDSSSSDEDDE---- 198

  Fly   122 SRPQSDGQQQYILCNTKLDICPPLLDVLGQMAGNVERRLMNSVGDLKCNKQQYKDIR-LPSNFGL 185
               ::..|...|...|.:.|.||.:.|                      |...|.:: .|:....
  Fly   199 ---EAPAQSAPIAIPTPVSIAPPQIAV----------------------KPPIKKLKPEPNPPAC 238

  Fly   186 VGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLPQYILEWA 250
            :.|.:..|  .:|...:|:.|..|||..:.:.::..:..:.::|:.|.|||||:|||||::.|..
  Fly   239 IHQTVYVP--VHRTTEVQNARLRLPILAEEQQVMETINENPIVIVAGETGSGKTTQLPQFLYEAG 301

  Fly   251 -AEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTTSGCLLR 314
             |:|:   .|.|::|||:|||::|:|::.|. ..|.:.|.|.||.....:..|.:...|.|.||:
  Fly   302 YAQHK---MIGVTEPRRVAAIAMSKRVAHEM-NLPESEVSYLIRFEGNVTPATRIKFMTDGVLLK 362

  Fly   315 ALAMDKKSFFKNTTHLIIDEAHERDLDTDFL--LLA--TKLELQKNPHLRLVLMSATM---DLEA 372
            .:..|  ......:.:|:||||||.:.||.|  ||:  ..|..::...|:|::||||:   |...
  Fly   363 EIETD--FLLSKYSVIILDEAHERSVYTDILVGLLSRIVPLRHKRGQPLKLIIMSATLRVSDFTE 425

  Fly   373 LSNYFG-GGTVMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGKETPSELLAAYYGGNT 436
            .:..|. ...::.||.|.|.|:| |.:                      |.||.:.:|..|....
  Fly   426 NTRLFKIPPPLLKVEARQFPVTI-HFQ----------------------KRTPDDYVAEAYRKTL 467

  Fly   437 IVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLP---------------- 485
            .:|..:..                |.:::::.|..::..|:.:|..:.|
  Fly   468 KIHNKLPE----------------GGILIFVTGQQEVNQLVRKLRRTFPYHHAPTKDVAKNGKVS 516

  Fly   486 ----------------------------------------------------------------- 485
                                                                             
  Fly   517 EEEKEETIDDAASTVEDPKELEFDMKRVIRNIRKSKKKFLAQMALPKINLDDYKLPGDDTEADMH 581

  Fly   486 --------------------------------REQITIILLHSQVDNSEQRKVFRTYP-GVRLKI 517
                                            |:.:.::.|:|.:.:.:|.::|...| |.|| .
  Fly   582 EQPDEDDEQEGLEEDNDDELGLEDESGMGSGQRQPLWVLPLYSLLSSEKQNRIFLPVPDGCRL-C 645

  Fly   518 ILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCY 582
            ::|||:.:||:|||.:.||:|.|..|.:.||.....|...:|:.|:|.|.||||||||:..|:||
  Fly   646 VVSTNVAETSLTIPHIKYVVDCGRQKTRLYDKLTGVSAFVVTYTSKASADQRAGRAGRISAGHCY 710

  Fly   583 RLYD----NDRMARMNLYTIPEIMRRTLDEICLLTKLAAPDKKIENFLALALDTPPKDAVMQSCS 643
            |||.    ||....   ::.|:|.::.::::.|..:....|:.:.    ....:||....:|:..
  Fly   711 RLYSSAVYNDCFED---FSQPDIQKKPVEDLMLQMRCMGIDRVVH----FPFPSPPDQVQLQAAE 768

  Fly   644 -RLKLLGVL--------DERDEVTPLGHIVAELPLGVQIGKCLVYSIYLRCLDSMIIIAAYHSVR 699
             ||.:||.|        |....||.|||:::..|:..:.||.|..|.....|...:.:.|..||:
  Fly   769 RRLIVLGALEVAKTENTDLPPAVTRLGHVISRFPVAPRFGKMLALSHQQNLLPYTVCLVAALSVQ 833

  Fly   700 DPFVLNIERGKKSGQQIS---------RVLFAGDG----MSDSLAVIKLY--EEFTNLKRKDIGD 749
            :  || ||.|.:..:.::         |..:|..|    :.|.:.:::..  .|:...:.: :.:
  Fly   834 E--VL-IETGVQRDEDVAPGANRFHRKRQSWAASGNYQLLGDPMVLLRAVGAAEYAGSQGR-LPE 894

  Fly   750 FCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLA------SSFNNDTNMIRLALTAGLY 808
            ||..|.:.:.||    |....||..:......:.:...|.      ...:.....:|..|.||:.
  Fly   895 FCAANGLRQKAM----SEVRKLRVQLTNEINLNVSDVELGVDPELKPPTDAQARFLRQILLAGMG 955

  Fly   809 PKLA-------YMDRENKNQL-----VAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTRTA 861
            .::|       ..|:|.:.:|     .|:.:....:..||.||.|      |.||:::.|    |
  Fly   956 DRVARKVPLADIADKEERRRLKYAYNCADMEEPAFLHVSSVLRQK------APEWVIYQE----A 1010

  Fly   862 DQISSLEHTTLVSGLMVALAGGKRFITEAHGSEMLLCLDSWIRLKC--------PA-EFGLQLHK 917
            .::.:.:.|.:..          |.||......:||    ::.|.|        || .|.....|
  Fly  1011 YELQNGDSTKMFI----------RGITAIEPEWLLL----YVPLLCNIREVREDPAPRFDKTSGK 1061

  Fly   918 VRMLTDREFAKLVATRKLSLMSDFIGPETVRRLLEADVP---STCLAEGKSLLDRDNCDN--DF 976
            :....|..|.|          |.:..|     |.|.::|   ..|...|..|||.:.|..  ||
  Fly  1062 IFCHVDATFGK----------SGWELP-----LGEVEMPLSEKACCYFGMFLLDGEVCSRLADF 1110

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	9/55 (16%)
		HrpA	208..>702	CDD:441249	151/629 (24%)
		OB_NTP_bind	799..884	CDD:400182	20/96 (21%)
kz	NP_476591.1	HrpA	260..>1071	CDD:441249	202/895 (23%)
		DEXHc_DHX37	260..439	CDD:350740	61/184 (33%)