Protein Alignment CG8915 and rha-2

DIOPT Version :9

• Sequence 1: NP_001285369.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 1073
• Identity: 251/1073 - (23%)
• Similarity: 410/1073 - (38%)
• Gaps: 321/1073 - (29%)

  Fly    16 RKKAQPMPEQAVVLVVNGRVTGGPKGTGKQKTRPGKNAKADAGDKLKS-EDEKMLRQLVDDFLQS 79
            |||.:...|::        .|||.|.....|.:........|..||.: :..|.|:|
 Worm    28 RKKLEKSGEKS--------ATGGKKNRNFAKEKEVAKLTKQAKRKLAAVQSRKALKQ-------- 76

  Fly    80 CEPEKQLPGLTKAQRSHVHRLAQHRGLKTVSKGPE------ENRVLFISRPQSDG---QQQYI-- 133
             ..|:...||.:.|.. ..:|.|......:||.||      |...:|..:.:::.   ||.|.
 Worm    77 -TQEELFAGLAEFQLD-PSKLCQLSSSTKLSKEPEKAPVFPEKLKVFSGKTKTEAKRTQQDYYPT 139

  Fly   134 ---------------------LCNT-KLDICP-PLLDVLGQMAGNVERRLMNSVGDLKCNKQQYK 175
                                 ..|| ::.|.| .|.||...:.||.|..|...|  :|....:..
 Worm   140 DDESSSEEEEEEEEGDNDIEDAGNTVEVKIEPIDLDDVDEAIDGNPETNLDQIV--VKREDDEES 202

  Fly   176 D----IRLPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGS 236
            |    :.||:...:..:::|    ..|::.||..|..|||:.:...|:..:..:.|.::.|.|||
 Worm   203 DNEDILALPTTTVINRKKVI----VERSKEIQKSRAELPIFAEEMRIVEAINENLVTVVCGETGS 263

  Fly   237 GKSTQLPQYILE--WAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCS 299
            ||:||:||::.|  :|:|...   |.:::|||:|||::::|:..|.  |....|.|.||.....|
 Worm   264 GKTTQIPQFLYEAGYASEGEL---IGITEPRRVAAIAMAQRVGVEL--AKPDEVSYQIRYEGTRS 323

  Fly   300 SNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFL--LLATKLELQKNP--HLR 360
            ..|.::..|.|.|::  .|::....|..:.::|||||||.:.:|.|  :|:..:.|:...  .||
 Worm   324 ETTNILFMTDGVLMK--EMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSKTARPLR 386

  Fly   361 LVLMSATMDLEALSN--YFGGGT--VMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGK 421
            ||:||||:.|:..::  .|...|  |:.|:.|.|.||: |.|                      |
 Worm   387 LVIMSATLRLDDFTHKKLFPLLTPKVIKVDARQFPVSV-HFE----------------------K 428

  Fly   422 ETPSELLAAYYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLP- 485
            .||.:.:|:.:.....:|..:                ..||::|::.|..::..|:.:|:...|
 Worm   429 RTPDDYIASAFRKTCRIHETL----------------PPGAILVFVTGQHEVKQLITKLKKRYPV 477

  Fly   486 ----------------------------------------------------------------- 485
                                                                             
 Worm   478 VYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPETEDFEDVDDGLMDGDDMNERGAAEA 542

  Fly   486 -----------------------------REQITIILLHSQVDNSEQRKVFRTYP-GVRLKIILS 520
                                         .|.:..:.|:|.:...:||:||...| |:|| .::|
 Worm   543 FDDYEEFENGDGDLSDGKVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDETPAGMRL-CVIS 606

  Fly   521 TNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLY 585
            ||:.:||:|||.:.||||.|..|.:.|||....|:..:..||||...||||||||:..|:.||||
 Worm   607 TNVAETSLTIPGVKYVIDGGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGRISAGHAYRLY 671

  Fly   586 DNDRMARMNLYTIPEIMRRTLDEICLLTKLAAPDKKIENFLALALDTPPKDAVMQSC-SRLKLLG 649
            .:........:..|||:.:..|::.|..| :....|:.||   ...:.|.:.:::|. .||..||
 Worm   672 SSAVYQDFVKFADPEILSKPADQLVLHLK-SMNIVKVVNF---PFPSAPDEQMLESAEKRLCRLG 732

  Fly   650 VLDERDE-------VTPLGHIVAELPLGVQIGKCLVYSIYLRCLDSMIIIAAYHSVRDPFVLNIE 707
            .|.|..:       :|.||..:|..||.....|.:..:.....:...|::.:..|||:|.:
 Worm   733 ALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVREPLI---- 793

  Fly   708 RGKKSGQQISRVLFAGDGMSDSLAVIK--LYE-----EFTNLKRKDIGDF--------------- 750
                   .:|.:  .||...::..::|  |.|     ..|..:|  :||.
 Worm   794 -------PVSSL--RGDTPEETKELMKNVLKERRRWCSHTGARR--LGDLKVLMHAASVAEQIKY 847

  Fly   751 ----CERNFICRNAMEMFVSA---ASTLRDTVYRIFRFS---EASARLASSF----NNDTNMIRL 801
                ||:       :.:.|.|   |..||..:..|...|   |.:|.|.|..    :....::|.
 Worm   848 NARECEK-------VGLRVKALVEARKLRQQLTNIVNASCKKEHAAALDSDLPPPTDQQAQLLRQ 905

  Fly   802 ALTAGLYPKLA-YMDRENKNQLVAEG-------------DP----------------LVQVSR-- 834
            .:.|....:|| .:||....:.|.:|             ||                ||||:.
 Worm   906 MVVASFSDRLARRVDRSVGQEEVQKGAYETTLIKGHVFIDPCSVVFTEEPEFVIYQELVQVNEKK 970

  Fly   835 ---SSCLRGKKKQKDLASEWILFVEKTRTADQI 864
               |.|...|:....||..:..:.|:.:..:.|
 Worm   971 LMTSVCAVDKEWLSRLAESYCNYGEQDKNQEPI 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_001285369.1	R3H	64..123	CDD:100064	15/64 (23%)
		DEXDc	214..395	CDD:214692	64/190 (34%)
		DEXDc	226..368	CDD:238005	53/147 (36%)
		HELICc	479..575	CDD:197757	41/191 (21%)
		HA2	648..733	CDD:214852	19/91 (21%)
		OB_NTP_bind	783..884	CDD:285018	25/121 (21%)
rha-2	NP_498895.1	HrpA	218..989	CDD:224557	203/847 (24%)
		DEXDc	254..394	CDD:238005	53/146 (36%)
		P-loop_NTPase	<350..>477	CDD:304359	41/165 (25%)
		HELICc	577..662	CDD:197757	39/85 (46%)
		HA2	730..822	CDD:214852	22/104 (21%)
		OB_NTP_bind	870..990	CDD:285018	25/119 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1643
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810