Protein Alignment CG8915 and rha-2

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: NP_498895.1
• Gene: rha-2 / 176207
• WormBaseID: WBGene00015525
• Length: 1148
• Species: Caenorhabditis elegans
• Alignment Length: 1073
• Identity: 251/1073 - (23%)
• Similarity: 410/1073 - (38%)
• Gaps: 321/1073 - (29%)

  Fly    16 RKKAQPMPEQAVVLVVNGRVTGGPKGTGKQKTRPGKNAKADAGDKLKS-EDEKMLRQLVDDFLQS 79
            |||.:...|::        .|||.|.....|.:........|..||.: :..|.|:|
 Worm    28 RKKLEKSGEKS--------ATGGKKNRNFAKEKEVAKLTKQAKRKLAAVQSRKALKQ-------- 76

  Fly    80 CEPEKQLPGLTKAQRSHVHRLAQHRGLKTVSKGPE------ENRVLFISRPQSDG---QQQYI-- 133
             ..|:...||.:.|.. ..:|.|......:||.||      |...:|..:.:::.   ||.|.
 Worm    77 -TQEELFAGLAEFQLD-PSKLCQLSSSTKLSKEPEKAPVFPEKLKVFSGKTKTEAKRTQQDYYPT 139

  Fly   134 ---------------------LCNT-KLDICP-PLLDVLGQMAGNVERRLMNSVGDLKCNKQQYK 175
                                 ..|| ::.|.| .|.||...:.||.|..|...|  :|....:..
 Worm   140 DDESSSEEEEEEEEGDNDIEDAGNTVEVKIEPIDLDDVDEAIDGNPETNLDQIV--VKREDDEES 202

  Fly   176 D----IRLPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGS 236
            |    :.||:...:..:::|    ..|::.||..|..|||:.:...|:..:..:.|.::.|.|||
 Worm   203 DNEDILALPTTTVINRKKVI----VERSKEIQKSRAELPIFAEEMRIVEAINENLVTVVCGETGS 263

  Fly   237 GKSTQLPQYILE--WAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCS 299
            ||:||:||::.|  :|:|...   |.:::|||:|||::::|:..|.  |....|.|.||.....|
 Worm   264 GKTTQIPQFLYEAGYASEGEL---IGITEPRRVAAIAMAQRVGVEL--AKPDEVSYQIRYEGTRS 323

  Fly   300 SNTVLMLTTSGCLLRALAMDKKSFFKNTTHLIIDEAHERDLDTDFL--LLATKLELQKNP--HLR 360
            ..|.::..|.|.|::  .|::....|..:.::|||||||.:.:|.|  :|:..:.|:...  .||
 Worm   324 ETTNILFMTDGVLMK--EMEQDVMLKKYSVILIDEAHERSMYSDVLIGMLSRIVPLRSKTARPLR 386

  Fly   361 LVLMSATMDLEALSN--YFGGGT--VMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGK 421
            ||:||||:.|:..::  .|...|  |:.|:.|.|.||: |.|                      |
 Worm   387 LVIMSATLRLDDFTHKKLFPLLTPKVIKVDARQFPVSV-HFE----------------------K 428

  Fly   422 ETPSELLAAYYGGNTIVHPDIDNDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLP- 485
            .||.:.:|:.:.....:|..:                ..||::|::.|..::..|:.:|:...|
 Worm   429 RTPDDYIASAFRKTCRIHETL----------------PPGAILVFVTGQHEVKQLITKLKKRYPV 477

  Fly   486 ----------------------------------------------------------------- 485
                                                                             
 Worm   478 VYETDKNGEVLVKGTKEWKEKKVEAAKSIKLEDFKEETPETEDFEDVDDGLMDGDDMNERGAAEA 542

  Fly   486 -----------------------------REQITIILLHSQVDNSEQRKVFRTYP-GVRLKIILS 520
                                         .|.:..:.|:|.:...:||:||...| |:|| .::|
 Worm   543 FDDYEEFENGDGDLSDGKVENSIGAPPADCEPLYCLPLYSLLSMGKQRRVFDETPAGMRL-CVIS 606

  Fly   521 TNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLTWISQADAKQRAGRAGRVCHGNCYRLY 585
            ||:.:||:|||.:.||||.|..|.:.|||....|:..:..||||...||||||||:..|:.||||
 Worm   607 TNVAETSLTIPGVKYVIDGGFEKRRLYDSITGVSRFAVCRISQASGDQRAGRAGRISAGHAYRLY 671

  Fly   586 DNDRMARMNLYTIPEIMRRTLDEICLLTKLAAPDKKIENFLALALDTPPKDAVMQSC-SRLKLLG 649
            .:........:..|||:.:..|::.|..| :....|:.||   ...:.|.:.:::|. .||..||
 Worm   672 SSAVYQDFVKFADPEILSKPADQLVLHLK-SMNIVKVVNF---PFPSAPDEQMLESAEKRLCRLG 732

  Fly   650 VLDERDE-------VTPLGHIVAELPLGVQIGKCLVYSIYLRCLDSMIIIAAYHSVRDPFVLNIE 707
            .|.|..:       :|.||..:|..||.....|.:..:.....:...|::.:..|||:|.:
 Worm   733 ALSESTKNGKTEARITKLGKTLAVFPLAPSYAKFIAMADQHNLMSHAILLISLLSVREPLI---- 793

  Fly   708 RGKKSGQQISRVLFAGDGMSDSLAVIK--LYE-----EFTNLKRKDIGDF--------------- 750
                   .:|.:  .||...::..::|  |.|     ..|..:|  :||.
 Worm   794 -------PVSSL--RGDTPEETKELMKNVLKERRRWCSHTGARR--LGDLKVLMHAASVAEQIKY 847

  Fly   751 ----CERNFICRNAMEMFVSA---ASTLRDTVYRIFRFS---EASARLASSF----NNDTNMIRL 801
                ||:       :.:.|.|   |..||..:..|...|   |.:|.|.|..    :....::|.
 Worm   848 NARECEK-------VGLRVKALVEARKLRQQLTNIVNASCKKEHAAALDSDLPPPTDQQAQLLRQ 905

  Fly   802 ALTAGLYPKLA-YMDRENKNQLVAEG-------------DP----------------LVQVSR-- 834
            .:.|....:|| .:||....:.|.:|             ||                ||||:.
 Worm   906 MVVASFSDRLARRVDRSVGQEEVQKGAYETTLIKGHVFIDPCSVVFTEEPEFVIYQELVQVNEKK 970

  Fly   835 ---SSCLRGKKKQKDLASEWILFVEKTRTADQI 864
               |.|...|:....||..:..:.|:.:..:.|
 Worm   971 LMTSVCAVDKEWLSRLAESYCNYGEQDKNQEPI 1003

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	15/61 (25%)
		HrpA	208..>702	CDD:441249	155/607 (26%)
		OB_NTP_bind	799..884	CDD:400182	21/101 (21%)
rha-2	NP_498895.1	HrpA	234..>1020	CDD:441249	200/843 (24%)