Protein Alignment CG8915 and l(2)37Cb

DIOPT Version :10

• Sequence 1: NP_573208.1
• Gene: CG8915 / 32715
• FlyBaseID: FBgn0030833
• Length: 976
• Species: Drosophila melanogaster
• Sequence 2: XP_319843.5
• Gene: l(2)37Cb / 1280046
• VectorBaseID: AGAMI1_007561
• Length: 891
• Species: Anopheles gambiae
• Alignment Length: 908
• Identity: 241/908 - (26%)
• Similarity: 387/908 - (42%)
• Gaps: 217/908 - (23%)

  Fly    55 ADAGDKLKSED---EKMLRQL------------VDDFLQSCE----------PEKQLPGLTKAQR 94
            |||..:|:.|.   ||:|.:|            .:|.:...|          ||.::....:..|
Mosquito    55 ADAAKRLRLETADREKLLPELRKQSRRQYLEKRKEDKVAELEADIRDDEYLFPEAEITERERRDR 119

  Fly    95 SHVHRLAQ----------------HRGLKTVSKGPEENRVLFISR---PQSD------------- 127
            .|..||.|                :|..|.|.||..|..|....|   |.|:
Mosquito   120 EHKKRLLQIAKDHEKARELERVQRYRMPKDVKKGEMEEYVEVDERERMPHSEQKKWEAEQLASAV 184

  Fly   128 -------------GQQQY-ILCNTKLDICPPLLDVLGQMAGNVERRLMNSVGDLKCNKQQYKDIR 178
                         .||:| :|.:.::|....|     ||||..:          |.:|.:..:
Mosquito   185 YGFGSKDAKERAAQQQEYELLLDEQIDFVEAL-----QMAGTKK----------KDDKPELTE-- 232

  Fly   179 LPSNFGLVGQRLIPPPQSNRNRNIQHERRSLPIYKQRESILNVLQRDQVLIIKGATGSGKSTQLP 243
                    .||        :...|:..::|||||..:|.::..:|...:|||:|.|||||:||:|
Mosquito   233 --------AQR--------KKMTIEETQKSLPIYPFKEDLIAAIQAHNILIIEGETGSGKTTQIP 281

  Fly   244 QYILEWAAEHRAPVRIVVSQPRRIAAISVSERISKERGEAPGTTVGYNIRMNRQCSSNTVLMLTT 308
            ||:.| |.......:|..:||||:||:||:.|:::|.....|..|||:||.....|..||:...|
Mosquito   282 QYLYE-AGFTNEGKKIGCTQPRRVAAMSVAARVAEEMAVKLGNEVGYSIRFEDCTSERTVIKYMT 345

  Fly   309 SGCLLRALAM--DKKSFFKNTTHLIIDEAHERDLDTDFLLLATKLELQKNPHLRLVLMSATMDLE 371
            .|.|.|....  |..|:    ..:||||||||.|.||.|....|...:....|:|::.|||:|.|
Mosquito   346 DGTLHREFLSEPDLASY----AVMIIDEAHERTLHTDILFGLVKDIARFRKDLKLLISSATLDAE 406

  Fly   372 ALSNYFGGGTVMDVEGRSFEVSIYHLEDILSKTGYMHPRMEKFLGKPTGKETPSELLAAYYGGNT 436
            ..|::|....:..:.||.:.|.|::.:
Mosquito   407 KFSDFFDKAPIFRIPGRRYPVDIFYTK-------------------------------------- 433

  Fly   437 IVHPDID--NDLIVSLLELLLRQGDAGAVIVYLPGYSDMTSLLARLESSLPR-----EQITIILL 494
              .|:.|  :..:||:|::...| ..|.::|:|.|..::.:....|:..:.|     :::.|:.:
Mosquito   434 --APEADYIDACVVSVLQIHATQ-PLGDILVFLTGQEEIEACQEMLQDRVKRLGSKLKELLILPI 495

  Fly   495 HSQVDNSEQRKVFRTYPGVRLKIILSTNIGQTSITIPDLLYVIDTGLAKMKTYDSTIDASQLTLT 559
            ::.:.:..|.|:|...|....|:||:|||.:||:||.:::||||.|.||...::|......|.:.
Mosquito   496 YANLPSDMQAKIFEPTPPNARKVILATNIAETSLTIDNIIYVIDPGFAKQNNFNSRTGMETLLVV 560

  Fly   560 WISQADAKQRAGRAGRVCHGNCYRLY----------DNDRMARMNLYTIPEIMRRTLDEICLLTK 614
            .||:|.|.|||||||||..|.|:|||          ||         |:|||.|..|....|:.|
Mosquito   561 PISKASANQRAGRAGRVAPGKCFRLYTAWAYNNELEDN---------TVPEIQRINLGNAVLMLK 616

  Fly   615 -LAAPDKKIENFLALALDTPPKDAVMQSCSRLKLLGVLDERDEVTPLGHIVAELPLGVQIGKCLV 678
             |...|....:|    ||.||...::.:..:|..||.|:...|:|.||..:||.|:...:.|.|:
Mosquito   617 TLGIHDLLHFDF----LDPPPHQTLILALEQLYALGALNHHGELTKLGRRMAEFPVDPMMAKMLL 677

  Fly   679 YSIYLRCLDSMIIIAAYHSVRDPF-------VLNIERGKKSGQQISRVLFAGDGMSDSLAVIKLY 736
            .|...:|.:.::.|||..||....       :::.:..:|:         ......|.|:::::|
Mosquito   678 ASEKYKCSEEIVSIAAMLSVNGAIFYRPKDKIIHADTARKN---------FNHRHGDHLSLMQVY 733

  Fly   737 EEFTNLKRKDIG-DFCERNFICRNAMEMFVSAASTLRDTVYRIFRFSEASARLASSFNNDTNMIR 800
            .::.   ..|.. .:|..|||...:|:    .|..:|:.:..:.:..|..   ..|..:||..:|
Mosquito   734 NQWV---ESDYSTQWCYENFIQYRSMK----RARDVREQLVGLMQRVEIE---MVSGESDTTNVR 788

  Fly   801 LALTAGLYPKLAYMDRENKNQLVAEGDPLVQVSRSSCLRGKKKQKDLASEWILFVEKTRTADQ 863
            .|:|||.:..:|.:.:....:.|..... |.:..:|.|     .:|| ..|:|:.|...|..:
Mosquito   789 KAITAGYFYHVARLSKSGNYKTVKHNQD-VMIHPNSAL-----FEDL-PRWLLYHELVFTTKE 844

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8915	NP_573208.1	R3H	67..123	CDD:460206	19/93 (20%)
		HrpA	208..>702	CDD:441249	166/513 (32%)
		OB_NTP_bind	799..884	CDD:400182	16/65 (25%)
l(2)37Cb	XP_319843.5	None