DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5162 and PNLIPRP1

DIOPT Version :9

Sequence 1:	NP_001285367.1	Gene:	CG5162 / 32709	FlyBaseID:	FBgn0030828	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001290064.1	Gene:	PNLIPRP1 / 5407	HGNCID:	9156	Length:	467	Species:	Homo sapiens

Alignment Length:	294	Identity:	86/294 - (29%)
Similarity:	124/294 - (42%)	Gaps:	50/294 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    93 YSPDINKMNFQLQTACEKKNFP--LTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDTIEVFSK 155
            :||:.....|.|.|.....||.  |.|..|..::..|.:.:|...:..|:....:.|...::..|
Human    47 WSPEKIGTRFLLYTNENPNNFQILLLSDPSTIEASNFQMDRKTRFIIHGFIDKGDESWVTDMCKK 111

  Fly   156 AYNCRGDVNFVAVDAARFVDTLYTWSAFNTEEIGENIALGLVKLLDLV------PVENIHLIGHS 214
            .:... :||.:.||..:.....||.:|.|...:|..:|    ::||::      |...:||||||
Human   112 LFEVE-EVNCICVDWKKGSQATYTQAANNVRVVGAQVA----QMLDILLTEYSYPPSKVHLIGHS 171

  Fly   215 LGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEALSGLMRGDAHFVDVIHSNPGVL---- 275
            ||||:.|.||.....|:     |||||||.:..|........|...||.||||||::...|
Human   172 LGAHVAGEAGSKTPGLS-----RITGLDPVEASFESTPEEVRLDPSDADFVDVIHTDAAPLIPFL 231

  Fly   276 --GKRDPVGDVDFYPGGMSPLAAGCFS-------------------VTCAHARSWEYFAETVFPG 319
              |....:|.:||:|.|...: .||..                   |.|.|.||::|:.|::.
Human   232 GFGTNQQMGHLDFFPNGGESM-PGCKKNALSQIVDLDGIWAGTRDFVACNHLRSYKYYLESIL-- 293

  Fly   320 NERNFMATRCNSISKLRD---FRCPGDEVP-MGY 349
            |...|.|..|.|......   |.||....| ||:
Human   294 NPDGFAAYPCTSYKSFESDKCFPCPDQGCPQMGH 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5162	NP_001285367.1	Lipase	94..369	CDD:278576	86/293 (29%)
CG5162	NP_001285367.1	Pancreat_lipase_like	99..365	CDD:238363	84/288 (29%)
PNLIPRP1	NP_001290064.1	Lipase	18..353	CDD:278576	86/294 (29%)
		Pancreat_lipase_like	52..349	CDD:238363	84/289 (29%)
		PLAT_PL	356..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145355
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840