DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5162 and Yp1

DIOPT Version :9

Sequence 1:	NP_001285367.1	Gene:	CG5162 / 32709	FlyBaseID:	FBgn0030828	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001285071.1	Gene:	Yp1 / 31939	FlyBaseID:	FBgn0004045	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	122/458 - (26%)
Similarity:	196/458 - (42%)	Gaps:	122/458 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LLALLLQLLVASIHAIEWSLPDVINSIGNVGTSIVDPSLLPTPQGLLEGSKQLIA-----GYPFE 70
            :|:||..|.||::     :.|:     |.:..| |:.:|.|:.  .|.|| ||.|     .:..|
  Fly     6 VLSLLACLAVAAL-----AKPN-----GRMDNS-VNQALKPSQ--WLSGS-QLEAIPALDDFTIE 56

  Fly    71 FVSNS--------LNVICSQALASNKIKSKYSPD--------------INKMNFQLQTACEKKNF 113
            .:.|.        |..:...:...:.::..|.|.              :..:|..:|...:|:||
  Fly    57 RLENMNLERGAELLQQVYHLSQIHHNVEPNYVPSGIQVYVPKPNGDKTVAPLNEMIQRLKQKQNF 121

  Fly   114 PLTSPESMWKSPLFDVKKKVVILATGWTTTVNGSDT--------IEVFSKAYNCR---------- 160
            .               :.:|.|:.||...|   |:|        ::.:.:.||.:
  Fly   122 G---------------EDEVTIIVTGLPQT---SETVKKATRKLVQAYMQRYNLQQQRQHGKNGN 168

  Fly   161 ---------------------------------GDVNFVAVDAARFVDTLYTWSAFNTEEIGENI 192
                                             ||:  :.:|....::|...::..:.|:.|..|
  Fly   169 QDYQDQSNEQRKNQRTSSEEDYSEEVKNAKTQSGDI--IVIDLGSKLNTYERYAMLDIEKTGAKI 231

  Fly   193 ALGLVKL---LDLVPVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITGLDPAKPCFNEGEAL 254
            ...:|::   ||: |.:.|||||.::|||:.|:|.:....||...:.|:|||||:|........|
  Fly   232 GKWIVQMVNELDM-PFDTIHLIGQNVGAHVAGAAAQEFTRLTGHKLRRVTGLDPSKIVAKSKNTL 295

  Fly   255 SGLMRGDAHFVDVIHSNPGVLGKRDPV--GDVDFYPGGMSPLAAGCFSVTCAHARSWEYFAETVF 317
            :||.||||.|||.||::  |.|...|:  |||||||.|.:....|..:|..|..|:..||||:|.
  Fly   296 TGLARGDAEFVDAIHTS--VYGMGTPIRSGDVDFYPNGPAAGVPGASNVVEAAMRATRYFAESVR 358

  Fly   318 PGNERNFMATRCNSISKLRDFRCPGDEVPMGYAVPQNIKGNYFLEVSASAPFGMHASVVR--SAH 380
            |||||:|.|...||:.:.:.....|....||.....:::|:|.|:|:..:|||.:|...:  |.|
  Fly   359 PGNERSFPAVPANSLQQYKQNDGFGKRAYMGIDTAHDLEGDYILQVNPKSPFGRNAPAQKQSSYH 423

  Fly   381 LEH 383
            ..|
  Fly   424 GVH 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5162	NP_001285367.1	Lipase	94..369	CDD:278576	93/344 (27%)
CG5162	NP_001285367.1	Pancreat_lipase_like	99..365	CDD:238363	92/321 (29%)
Yp1	NP_001285071.1	Abhydrolase	183..406	CDD:304388	78/227 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446013
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007604
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.840