DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5162 and lpl

DIOPT Version :9

Sequence 1:	NP_001285367.1	Gene:	CG5162 / 32709	FlyBaseID:	FBgn0030828	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_571202.1	Gene:	lpl / 30354	ZFINID:	ZDB-GENE-990415-139	Length:	511	Species:	Danio rerio

Alignment Length:	272	Identity:	85/272 - (31%)
Similarity:	124/272 - (45%)	Gaps:	53/272 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 PESMWKSPLFDVKKKVVILATGWTTT-VNGSDTIEVFSKAYNCRGDVNFVAVDAARFVDTLYTWS 181
            |:|: |...|:.:.|..|:..|||.| :..|...::.:..|......|.:.||........|..|
Zfish    80 PQSI-KDCNFNTETKTFIVIHGWTVTGMFESWVPKLVTALYEREPSANVIVVDWLSRAQQHYPTS 143

  Fly   182 AFNTEEIGENIALGLVKLLDLV------PVENIHLIGHSLGAHIVGSAGRHLQHLTNQTIPRITG 240
            |..|:.:|:::|    |.::.:      |.|.:||:|:|||||:.|.||.    ||...:.||||
Zfish   144 ASYTKLVGKDVA----KFVNWLQAEIDYPWEKLHLLGYSLGAHVAGIAGL----LTKHKVNRITG 200

  Fly   241 LDPAKPCFNEGEALSGLMRGDAHFVDVIHSN-----PGVLGKRDPVGDVDFYPGGMSPLAAGC-- 298
            :|||.|.|...::||.|...||:||||:|:|     ...:|.:.|||.:|.||.| .....||
Zfish   201 MDPAGPTFEYADSLSTLSPDDANFVDVLHTNTRGSPDRSIGIQRPVGHIDIYPNG-GTFQPGCDL 264

  Fly   299 ----------------FSVTCAHARSWEYFAETVFPGNERNFMATRCNSISKL--------RDFR 339
                            ..|.|:|.||...|.:::. ..:...||.||:|....        |..|
Zfish   265 QNTMLMVATTGLRNMDQIVKCSHERSIHLFIDSLV-NQDHESMAFRCSSRDSFNKGMCLSCRKNR 328

  Fly   340 CPGDEVPMGYAV 351
            |.    .:||||
Zfish   329 CN----KVGYAV 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5162	NP_001285367.1	Lipase	94..369	CDD:278576	85/272 (31%)
CG5162	NP_001285367.1	Pancreat_lipase_like	99..365	CDD:238363	85/272 (31%)
lpl	NP_571202.1	lipo_lipase	52..492	CDD:132274	85/272 (31%)
		Pancreat_lipase_like	56..353	CDD:238363	85/272 (31%)
		PLAT	360..484	CDD:294016
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578625
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.940