DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18258 and lipca

DIOPT Version :9

Sequence 1:	NP_573201.1	Gene:	CG18258 / 32708	FlyBaseID:	FBgn0265267	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	301	Identity:	88/301 - (29%)
Similarity:	124/301 - (41%)	Gaps:	65/301 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   178 SSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWT------------TSINNSNSGPVAKAY 230
            :.|.|   ::.|.|...| :..||....|..:.|.||:            .|...|:.|.:
Zfish    55 TEDTC---ALELFQPHTL-DACGFNSSLPLAIIIHGWSVDGMMEKWISRLASALKSSEGNI---- 111

  Fly   231 LCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNTSYVTKQF-----HLVGHSLGA 290
                  ||||.|........|..:|.||.::|..:|..|..|..   .|||     ||:|:||||
Zfish   112 ------NVLIADWLTLAHQHYPIAAQNTRIVGQDIAHLLSWLED---FKQFPLGKVHLIGYSLGA 167

  Fly   291 QIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDIIHT----NPGM-FG 350
            .|:|.||.|.  ...|:.|.||||||||.|.|...:..:.|...||:|||.|||    ..|: .|
Zfish   168 HISGFAGSNL--AMSGRTLGRITGLDPAGPMFEGMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVG 230

  Fly   351 TSKRAGDADFFVQGRIPFKPGCE-----------------SLDPISCSHQRAVDYWTETVYPSNG 398
            ..:.....||:..|. .|:|||:                 ....:.|:|:|||..:.:::. :..
Zfish   231 IKQPVAHFDFYPNGG-SFQPGCQLHMQNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLL-NKD 293

  Fly   399 NDFLAKRCKRYSELLLGNYC----KNTNTVMGYAAKATDLG 435
            ...:|.:|...:....|| |    ||....:||..|....|
Zfish   294 KQIMAYKCSDNTAFDKGN-CLDCRKNRCNTLGYDIKKVRTG 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18258	NP_573201.1	Pancreat_lipase_like	172..443	CDD:238363	88/301 (29%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	88/301 (29%)
		Pancreat_lipase_like	54..344	CDD:238363	88/301 (29%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.840