DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18258 and Pnliprp2

DIOPT Version :9

Sequence 1:	NP_573201.1	Gene:	CG18258 / 32708	FlyBaseID:	FBgn0265267	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_035258.2	Gene:	Pnliprp2 / 18947	MGIID:	1336202	Length:	482	Species:	Mus musculus

Alignment Length:	286	Identity:	91/286 - (31%)
Similarity:	130/286 - (45%)	Gaps:	45/286 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 GVVR--SKLIP----DMSRMSFLLRSSDDCQNTSIPLTQAEQLWNTTGFYQDRPTVLFITGWTTS 217
            |:::  ||:.|    |:. ..|||.::::..|..|.........|.:.|..||.|...|.|:
Mouse    49 GMIQRPSKIFPWSPEDID-TRFLLYTNENPNNYQIISATDPATINASNFQLDRKTRFIIHGF--- 109

  Fly   218 INNSNSG---PVAKAYLCRNDTNVLILDAANFIDTLYTWSALNTEVIGDYLAKALLRLNT--SYV 277
            |:....|   .:.|........|.:.:|......|.||.::.||.|:|..:|..:..|:|  .|.
Mouse   110 IDKGEEGWLLDMCKKMFQVEKVNCICVDWKRGSRTEYTQASYNTRVVGAEIAFLVQVLSTEMGYS 174

  Fly   278 TKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPANPCFYDGNELEGLRSGDARFVDII 342
            .:..||:|||||:.:||.||   |||.|.  :.||||||||.|||....|...|...||.|||:|
Mouse   175 PENVHLIGHSLGSHVAGEAG---RRLEGH--VGRITGLDPAEPCFQGLPEEVRLDPSDAMFVDVI 234

  Fly   343 HTNPGM------FGTSKRAGDADFFVQGRIPFKPGCES--LDPI--------------SCSHQRA 385
            ||:...      ||.|::.|..|||..|.... |||:.  |..|              :|:|.|:
Mouse   235 HTDSAPIIPYLGFGMSQKVGHLDFFPNGGKEM-PGCQKNILSTIVDINGIWEGTRNFAACNHLRS 298

  Fly   386 VDYWTETVYPSNGNDFLAKRCKRYSE 411
            ..|:..::.  |.:.||...|..|.:
Mouse   299 YKYYASSIL--NPDGFLGYPCSSYEK 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18258	NP_573201.1	Pancreat_lipase_like	172..443	CDD:238363	86/267 (32%)
Pnliprp2	NP_035258.2	Lipase	31..367	CDD:278576	91/286 (32%)
		Pancreat_lipase_like	65..363	CDD:238363	86/270 (32%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	106..118		4/14 (29%)
		Required for galactolipase activity. /evidence=ECO:0000250\|UniProtKB:P54317	270..292		2/21 (10%)
		PLAT_PL	370..482	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840