DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18258 and PNLIPRP3

DIOPT Version :9

Sequence 1:	NP_573201.1	Gene:	CG18258 / 32708	FlyBaseID:	FBgn0265267	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001011709.2	Gene:	PNLIPRP3 / 119548	HGNCID:	23492	Length:	467	Species:	Homo sapiens

Alignment Length:	332	Identity:	99/332 - (29%)
Similarity:	138/332 - (41%)	Gaps:	59/332 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 DQLNQFVVGLPLDLGFSTLNYICSTIVDLGVVRSKLIPDMSRMSFLL---RSSDDCQNTSIPLTQ 191
            ::|..|..|||....|||           .:|.....|:.....|||   .:.:..|..|...:.
Human    23 ERLGCFKDGLPWTRTFST-----------ELVGLPWSPEKINTRFLLYTIHNPNAYQEISAVNSS 76

  Fly   192 AEQLWNTTGFYQDRPTVLFITGWTTSINNSNSGPVAKAYLCRNDTNVLILDAANFIDTLYTWSAL 256
            ..|   .:.|..|:.|.:.|.||.|  :......:....|...|.|.:.||..|. ...|..:..
Human    77 TIQ---ASYFGTDKITRINIAGWKT--DGKWQRDMCNVLLQLEDINCINLDWING-SREYIHAVN 135

  Fly   257 NTEVIG---DYLAKALLRLNTSYVTKQFHLVGHSLGAQIAGSAGRNYRRLSGGQILKRITGLDPA 318
            |..|:|   .|....|:: ...|...:.||:||||||.:||.||   .|:.|   |.||||||||
Human   136 NLRVVGAEVAYFIDVLMK-KFEYSPSKVHLIGHSLGAHLAGEAG---SRIPG---LGRITGLDPA 193

  Fly   319 NPCFYDGNELEGLRSGDARFVDIIHTNPGMF------GTSKRAGDADFFVQGRIPFKPGCESL-D 376
            .|.|::..:...|...||.|||:||||....      ||....|..||:..|. ...||||.| .
Human   194 GPFFHNTPKEVRLDPSDANFVDVIHTNAARILFELGVGTIDACGHLDFYPNGG-KHMPGCEDLIT 257

  Fly   377 PI----------------SCSHQRAVDYWTETVYPSNGNDFLAKRCKRYSELLLGN--YC-KNTN 422
            |:                .|:|.|:..::.|::.  |.:.|:|..|:.|:....||  :| |...
Human   258 PLLKFNFNAYKKEMASFFDCNHARSYQFYAESIL--NPDAFIAYPCRSYTSFKAGNCFFCSKEGC 320

  Fly   423 TVMGYAA 429
            ..||:.|
Human   321 PTMGHFA 327

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18258	NP_573201.1	Pancreat_lipase_like	172..443	CDD:238363	89/290 (31%)
PNLIPRP3	NP_001011709.2	Lipase	18..352	CDD:278576	99/332 (30%)
		Pancreat_lipase_like	52..348	CDD:238363	89/292 (30%)
		PLAT_PL	355..467	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165145263
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.840