Protein Alignment rnf145b and Rnf145

DIOPT Version :10

• Sequence 1: NP_956057.1
• Gene: rnf145b / 327056
• ZFINID: ZDB-GENE-030131-5264
• Length: 685
• Species: Danio rerio
• Sequence 2: NP_083138.2
• Gene: Rnf145 / 74315
• MGIID: 1921565
• Length: 663
• Species: Mus musculus
• Alignment Length: 631
• Identity: 529/631 - (83%)
• Similarity: 574/631 - (90%)
• Gaps: 16/631 - (2%)

Zfish     1 MAMKARLESVLNVGLRIPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPVFQYKYIALYLHYVGYIL 65
            ||.|.:||:||||.||:||||||:||||||||||||:||||||||||:|||||:||.:|||||||
Mouse     1 MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYIL 65

Zfish    66 SLVLLTLPRQHLVQLYLYVLTALLLFAGHQLSRDYVRGELDSGYEGPLYLEPLSMNRFTTALIGQ 130
            |:||||||||||||||||.:|||||:||||:||||||.||:|.||||:|||||||||||||||||
Mouse    66 SVVLLTLPRQHLVQLYLYFVTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQ 130

Zfish   131 VVVCTLCSCVMQTRQIWLFSAHLLPLVARLCLVPLETIVFINRFAMIFTGLEVLYFIASNLLVPY 195
            :||||||||||:|:||||||||:|||:||||||||||||.||:|||||||||||||:.|||||||
Mouse   131 LVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPY 195

Zfish   196 NLAKTAYRELVQVVEVYGLLALGMSLWNQLVLPVLFMCFWLVLFALQIYTYFSTRDQPPSRERLL 260
            ||||:||||||||||||||||||||||||||:|||||.|||||||||||:||||||||.||||||
Mouse   196 NLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLL 260

Zfish   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDNAMHRGMTEGITLLILA 325
            ||||||||||||||||||||||||||||||||||||||||||||||||.||:||||||:||||||
Mouse   261 FLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILA 325

Zfish   326 VQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390
            ||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 VQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLL 390

Zfish   391 VFPAYMAYMICQFFRMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEEFRKAPVENMDEVIYYVN 455
            ||||||||||||||.|||||||||||||||||||||||.||||||||||||.||||||:||||||
Mouse   391 VFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVN 455

Zfish   456 GTYRLLEFLVAVCVVAYGVSETLFGEWTVMGSTIILVHSYYNVWLRAQLGWQSFLLRRDAVHKIQ 520
            ||||||||:||:||||||||||:|||||||||.||.:||||||||||||||:|||||||||:||:
Mouse   456 GTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIK 520

Zfish   521 SMPTASTLQLQQHNDICSICFQDMKSAVITPCSHFFHAACLKKWLYVQETCPLCHGQLKSQLQPT 585
            |:|.|:..||::|||||:||:|||||||||||||||||.|||||||||:||||||..||:..|
Mouse   521 SLPVATQEQLEKHNDICAICYQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQ-- 583

Zfish   586 SSPGTPTQGTPAANQNPREVEQE---QRQPQVE-------LNTEEG 621
                .|..||.||.|.|...||.   |..|:..       ..|:||
Mouse   584 ----LPGLGTEAAPQPPAGAEQNIVLQEGPEPPDHESPPGTGTQEG 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf145b	NP_956057.1	TRC8_N	8..506	CDD:463960	451/497 (91%)
		RING-H2_RNF145	533..575	CDD:319598	37/41 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..685		15/50 (30%)
Rnf145	NP_083138.2	TRC8_N	8..506	CDD:463960	451/497 (91%)
		YLYF motif. /evidence=ECO:0000269|PubMed:29374057	81..84		2/2 (100%)
		HRD1	<520..627	CDD:227568	61/112 (54%)
		RING-H2_RNF145	533..575	CDD:319598	37/41 (90%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	587..663		13/39 (33%)