Protein Alignment TTLL1A and TTLL1B

DIOPT Version :9

• Sequence 1: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_729025.1
• Gene: TTLL1B / 326203
• FlyBaseID: FBgn0052238
• Length: 487
• Species: Drosophila melanogaster
• Alignment Length: 421
• Identity: 247/421 - (58%)
• Similarity: 316/421 - (75%)
• Gaps: 18/421 - (4%)

  Fly    56 IYYSTDWDKSALVSNFQKRGWLQVPSFNG--EWNFYWACTQNCRYIFGIDHPYRMRSDQVINHFP 118
            |.:.||.|||.||:||:||||.||   ||  :|:||||..|.||.||.:|..|||..:|:|||||
  Fly    76 IGFCTDLDKSVLVNNFEKRGWHQV---NGDDDWHFYWAGVQTCRNIFSVDSGYRMHDNQMINHFP 137

  Fly   119 NSIELSRKDLLIKNIKRYRKDLERRGDPLAQSHPPDTKLGIGGTRYKHLDIIPMTFVLPSDYQMF 183
            |..||||||||:||||||||||||.|:|||:....:..   .||||.:||.:|.|||||:||.||
  Fly   138 NHYELSRKDLLVKNIKRYRKDLERDGNPLAEKTESNNS---SGTRYLYLDFVPTTFVLPADYNMF 199

  Fly   184 VEVFHRNPASTWIVKPCSKSQGVGIYLVNKLSKLKKFAYDAR-TFYPQINRDTCVISKYIDNPLL 247
            ||.:.:.|.||||:|||.||||.||:|:||||||||::.:|: .|:|||.:::.|||:|||||||
  Fly   200 VEEYRKFPLSTWIMKPCGKSQGAGIFLINKLSKLKKWSREAKGPFHPQIAKESYVISRYIDNPLL 264

  Fly   248 IGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYDE--TEIDNVFMHLTNVSIQKTNQEYNS 310
            ||||||||||:|||.:|.||||||:|:|||||||.|||.  ||:||:::||||||:||...|||:
  Fly   265 IGGKKFDLRLYVLVASFRPLKAYLFKQGFCRFCTVKYDTSVTELDNMYVHLTNVSVQKHGGEYNT 329

  Fly   311 IHGGKWPLQNLWLYLDSLRGEGVSDMLWSRITATIRHSLDAVAPVMANDRHCFEVYGYDIIIDNN 375
            :|||||.:|||.|||:..||:.|:|.|:..|:..|.|||.|||||||:||||||.|||||||||.
  Fly   330 LHGGKWSVQNLALYLEGTRGKEVTDRLFGAISWLIVHSLRAVAPVMASDRHCFECYGYDIIIDNA 394

  Fly   376 LKPWLIEINTSPSMHSTTTNDRMLKSRLIDNVLDVVVPPNCMPNEHWDKTPNPELLKNFTVLMPI 440
            |||||:|:|.|||:.|||.|||:||.:||||:|.||:||:.:|:..|:|.|:.:.|.||.:|:
  Fly   395 LKPWLVEVNASPSLTSTTVNDRILKYKLIDNILSVVLPPDGVPDVRWNKVPSADALGNFELLI-- 457

  Fly   441 SPCKPKEQVPVRRKGRLSKKKKSKSTTASSG 471
                 .|::..:.:...:....:.|.|:..|
  Fly   458 -----DEELAAQDEQHQNSSSNTHSKTSKMG 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1A	NP_573197.2	TTL	107..419	CDD:281171	205/314 (65%)
TTLL1B	NP_729025.1	TTL	126..438	CDD:281171	205/314 (65%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438022
Domainoid	1	1.000	252	1.000	Domainoid score	I1134
eggNOG	1	0.900	-	-		E1_KOG2157
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	277	1.000	Inparanoid score	I1771
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57390
OrthoDB	1	1.010	-	-		D315374at33208
OrthoFinder	1	1.000	-	-		FOG0001326
OrthoInspector	1	1.000	-	-		otm14644
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12241
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1567
SonicParanoid	1	1.000	-	-		X4704
	12	11.940