Protein Alignment TTLL1A and Ttll8

DIOPT Version :10

• Sequence 1: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_056840443.1
• Gene: Ttll8 / 315214
• RGDID: 1306462
• Length: 927
• Species: Rattus norvegicus
• Alignment Length: 602
• Identity: 143/602 - (23%)
• Similarity: 241/602 - (40%)
• Gaps: 158/602 - (26%)

  Fly     9 PLRNLRQKCGGSCTSDDDLPEVKLITQPINGLHYIRNRLRPPKSRNGI-------------YYST 60
            ||:|:.    |...|.:.....::..:..:.:|.:.:||    .:|.|             |:|.
  Rat   236 PLQNVE----GEDKSAETKENQEIALERFDDIHDVMSRL----VKNEIPYLLWTIKRDVVDYHSL 292

  Fly    61 DWD--------------KSALVSNFQKRGWLQVPSFNGEW-NFYWACTQNCRYIFGIDHPYRMRS 110
            ..|              |..|..|.:...|....:.|..: ..|..||::.:..| :|...|..:
  Rat   293 TCDQMLNHYGKTASFTTKIGLCLNMRSLPWYVQANPNTFFPRCYGLCTESEKQEF-LDDFRRTVA 356

  Fly   111 DQVIN---HFPNSIELSRKDLLIKNIKRYRKDLERRGDPLAQSHP--PDTKLG------------ 158
            ..::.   |..|....::        .:.:|:..:.|||..:..|  ||.||.
  Rat   357 ASILKWVVHHQNYCNRAK--------GKSKKEEAKNGDPSPKKDPDNPDLKLPSLSGQVVDTACK 413

  Fly   159 -----IGGTRYKHLDIIPMTFVLPSD------YQMFVEVFHRNPAST------------------ 194
                 :|...::.:|:...:....|:      .|.:..:.|.|.:.|
  Rat   414 VCQAYLGQLEHEDIDLSDASAEALSEEEWNDLTQQYYLLVHGNASITDSRSYFAQCQALLSKISS 478

  Fly   195 -------------WIVKPCSKSQGVGIYLVNKLSK-LKKFAYDARTFYPQINRDT-CVISKYIDN 244
                         ||:||.:||:|..|..::::.. |...|.|::|     .:|. .|:.|||:.
  Rat   479 VNPQTEIDGIRNIWIIKPAAKSRGRDIVCMDRVENILDLVATDSQT-----TKDNKWVVQKYIET 538

  Fly   245 PLLIGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYDETEIDNVFMHLTNVSIQ---KTNQ 306
            |:||...|||:|.:.|||.:|||..:.|||.:.||.|:::...::|:. :||.|.|||   |.::
  Rat   539 PMLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKLDSA-IHLCNNSIQRRLKNDK 602

  Fly   307 EYNSIHGGKWPLQNLWL------YLDSLRGEGVS--DMLWSRITATIRHSLDAVAPVMANDRHCF 363
            |.:.:    .|..|:|.      ||.. ||.|.:  .:::..:...:.:::......:...::.|
  Rat   603 ERSPL----LPCHNMWTSTRFQEYLQK-RGRGGTWGSIIYPSMKRAVTNAMRVAQDHVEARKNSF 662

  Fly   364 EVYGYDIIIDNNLKPWLIEINTSPSMHSTTTNDRMLKSRLIDNVLDVVV----PPNCMPNEHWDK 424
            |:||.|.|:..:.||||||||:||:||.:|.....|.:::.::.:.|||    ..||       .
  Rat   663 ELYGADFILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVVVDRKLDRNC-------D 720

  Fly   425 TPNPELL-KNFTVLMP-----------ISPCKPKEQVPVRRKGRLSKKKKSKSTTASSGICSFTP 477
            ..|.||| :...|.:|           ||..|.|:|:|.......|.......|.|.|.    .|
  Rat   721 IGNFELLWRQPAVELPPFNGSDLCVEGISVKKAKKQMPPIANLGFSDSLLDAPTKARSA----RP 781

  Fly   478 PPAEGETKIKRSNKVVK 494
            .|   ||.|..|...|:
  Rat   782 LP---ETVIGPSRMTVR 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1A	NP_573197.2	TTL	107..419	CDD:397308	97/387 (25%)
Ttll8	XP_056840443.1	TTL	<489..711	CDD:397308	74/232 (32%)