Protein Alignment TTLL1A and Ttll8

DIOPT Version :10

• Sequence 1: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_006521018.1
• Gene: Ttll8 / 239591
• MGIID: 1922902
• Length: 928
• Species: Mus musculus
• Alignment Length: 685
• Identity: 139/685 - (20%)
• Similarity: 249/685 - (36%)
• Gaps: 228/685 - (33%)

  Fly     5 RQTSPLRNLRQKCGGSCTSDDDLPEVKL---ITQPING-----LHYIRNRLRPPKSRNGIYYSTD 61
            |:.|.....|:|...:.:..|...|.||   |.|.::.     .:.|..:|.....:....:|..
Mouse   144 REASMENGERKKLSSTLSDGDHKEENKLKQGIPQDLSSSPKLDRYKIARQLTEKAIKERKIFSIY 208

  Fly    62 WDKSALVSNFQKRGWLQVPSFNGEWNFYWACTQN------------------------------- 95
            .....:.:..:::||::     .::||:....||
Mouse   209 GHYPVIRATLRRKGWVE-----KKFNFFPKALQNLGSEDKSAETKENQEIALERFDDIHDVMSRL 268

  Fly    96 ----CRYIFG------IDHPYRMRSDQVINHFPNSIELSRKDLLIKNIK---------------- 134
                ..|:..      :|: :.:..||::||:..:...:.|..|..|::
Mouse   269 VKNEIPYLLWTIKRDVVDY-HSLTCDQMLNHYGKTASFTTKIGLCLNMRSLPWYVQANPNTFFPR 332

  Fly   135 -----------------------------------------RYRKDLERRGDPLAQSHP--PDTK 156
                                                     :.:|:..:..||..:..|  ||.|
Mouse   333 CYGLCTESEKQEFLDDFRRTVAASILKWVVLHQNYCSKVKGKSKKEEAKNSDPSPKKDPENPDLK 397

  Fly   157 LG-----------------IGGTRYKHLDIIPMTFVLPSD------YQMFVEVFHRNPAST---- 194
            |.                 :|...::.:|:...:....|:      .|.:..:.|.|.:.|
Mouse   398 LPSLSGQVVDTACKVCQAYLGQLEHEDIDVSEASTEALSEEEWNDLTQQYYLLVHGNASITDSKS 462

  Fly   195 ---------------------------WIVKPCSKSQGVGIYLVNKLSK-LKKFAYDARTFYPQI 231
                                       ||:||.:||:|..|..::::.. |...|.|::|
Mouse   463 YFAQCQALLSKISSVNPQTEIDGIRNIWIIKPAAKSRGRDIVCMDRVENILSLVAADSQT----- 522

  Fly   232 NRDT-CVISKYIDNPLLIGGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEKYDETEIDNVFMH 295
            .:|. .|:.|||:.|:||...|||:|.:.|||.:|||..:.|||.:.||.|:::...::|:. :|
Mouse   523 TKDNKWVVQKYIETPMLIYDTKFDIRQWFLVTDWNPLTIWFYKESYLRFSTQRFSLDKLDSA-IH 586

  Fly   296 LTNVSIQ---KTNQEYNSIHGGKWPLQNLWL------YLDSLRGEGVS--DMLWSRITATIRHSL 349
            |.|.|||   |.::|.:.:    .|..|:|.      ||.. ||.|.:  .:::..:...:.:::
Mouse   587 LCNNSIQRRLKNDKERSPL----LPCHNMWTSTRFQEYLQK-RGRGGTWGSIIYPSMKRAVTNAM 646

  Fly   350 DAVAPVMANDRHCFEVYGYDIIIDNNLKPWLIEINTSPSMHSTTTNDRMLKSRLIDNVLDVVV-- 412
            ......:...::.||:||.|.|:..:.||||||||:||:||.:|.....|.:::.::.:.|||
Mouse   647 RVAQDHVEARKNSFELYGADFILGRDFKPWLIEINSSPTMHPSTPVTAQLCAQVQEDTIKVVVDR 711

  Fly   413 --PPNCMPNEHWDKTPNPELLKNFTVLMPISPCKPKEQVPVRRKGRL-------SKKKKSKSTTA 468
              ..||.             :.||.:|..    :|..::|......|       .|.||.....|
Mouse   712 KLDRNCD-------------IGNFELLWR----QPAVELPPFNGSDLCVEGISVKKAKKQMPPIA 759

  Fly   469 SSGICSF---TPPPAEG-----ETKIKRSNKVVKR 495
            |.|:...   .||....     ||.|:.....|::
Mouse   760 SVGLSESLLDAPPKVRSARALMETVIRPPRTTVRQ 794

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1A	NP_573197.2	TTL	107..419	CDD:397308	100/441 (23%)
Ttll8	XP_006521018.1	TTL	<487..709	CDD:397308	74/232 (32%)