Protein Alignment TTLL1A and TTL

DIOPT Version :9

• Sequence 1: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_714923.1
• Gene: TTL / 150465
• HGNCID: 21586
• Length: 377
• Species: Homo sapiens
• Alignment Length: 407
• Identity: 104/407 - (25%)
• Similarity: 178/407 - (43%)
• Gaps: 92/407 - (22%)

  Fly    51 KSRNGIYYSTDWDKSALVSNFQKRGWLQVPSFN---GEWNFYWACTQNCRYIFGIDHPYRMRSD- 111
            :..|...|: :..:..|.:...||.....|.||   ||.|         |..||     |:..:
Human     7 RDENSSVYA-EVSRLLLATGHWKRLRRDNPRFNLMLGERN---------RLPFG-----RLGHEP 56

  Fly   112 ---QVINHFPNSIELSRKDLLIKNIKRYRKDLERRGDPLAQS----------HPPDTKLGI---- 159
               |::|::..:.:|.||..|:|.||        ....||:|          :|.:.|..:
Human    57 GLVQLVNYYRGADKLCRKASLVKLIK--------TSPELAESCTWFPESYVIYPTNLKTPVAPAQ 113

  Fly   160 GGTRYKHLDIIPMTFVLPSDYQMFVEVFHR----NPASTWIVKPCSKSQGVGIYLVNKLSKLKKF 220
            .|.:      .|::.....:.:.|:..::|    ...:.||.|..:.::|.||.:.::.|:|..|
Human   114 NGIQ------PPISNSRTDEREFFLASYNRKKEDGEGNVWIAKSSAGAKGEGILISSEASELLDF 172

  Fly   221 AYDARTFYPQINRDTCVISKYIDNPLLI--GGKKFDLRLFVLVTTFNPLKAYLYKEGFCRFCTEK 283
            ..:....:        ||.||:::|||:  |.:|||:|.:|||.  :....|||:||..|..:|.
Human   173 IDNQGQVH--------VIQKYLEHPLLLEPGHRKFDIRSWVLVD--HQYNIYLYREGVLRTASEP 227

  Fly   284 YDETEIDNVFMHLTNVSIQKTNQEYNSIHGGKWPLQNLWL------YLDSLRGEGVSDMLWSRIT 342
            |......:...||||..|||   ||:..: ||:...|...      ||.|.....:...:..:|.
Human   228 YHVDNFQDKTCHLTNHCIQK---EYSKNY-GKYEEGNEMFFKEFNQYLTSALNITLESSILLQIK 288

  Fly   343 ATIRHSLDAVAPVMANDRH----CFEVYGYDIIIDNNLKPWLIEINTSPSMHSTTTNDRMLKSRL 403
            ..||:.|.:|.|.::. :|    .|:::|:|.::|..||.||||:|.:|:.      .:.|.:.|
Human   289 HIIRNCLLSVEPAIST-KHLPYQSFQLFGFDFMVDEELKVWLIEVNGAPAC------AQKLYAEL 346

  Fly   404 IDNVLDVVV-----PPN 415
            ...::|:.:     ||:
Human   347 CQGIVDIAISSVFPPPD 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1A	NP_573197.2	TTL	107..419	CDD:281171	90/348 (26%)
TTL	NP_714923.1	TTL	81..367	CDD:397308	82/318 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2157
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5560
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1567
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.790