Protein Alignment TTLL1A and ttll3

DIOPT Version :10

• Sequence 1: NP_573197.2
• Gene: TTLL1A / 32704
• FlyBaseID: FBgn0030823
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_002941012.2
• Gene: ttll3 / 100497708
• XenbaseID: XB-GENE-6035679
• Length: 749
• Species: Xenopus tropicalis
• Alignment Length: 646
• Identity: 141/646 - (21%)
• Similarity: 249/646 - (38%)
• Gaps: 194/646 - (30%)

  Fly     4 RRQTSPLR-NLRQKCGGSCTSDDDLPEVKLITQ---------PINGLH-YIRNRLRPPKSRNGIY 57
            :...||.: ::.:|......:.|.|.:.||:.:         .|.|.: |||:.||
 Frog    33 KHDVSPTKGHVSKKTHTKKINPDSLKQAKLLVEKAIQENKIFTIQGYYPYIRSGLR--------- 88

  Fly    58 YSTDWDKSALVSNFQK---------RGWLQVPS---FNGEWNFYWACTQNCRYIFGIDHPYRMRS 110
             |..|    :..||.|         .|...:.|   .|.:.||.|..|.|     .:|... :::
 Frog    89 -SRGW----VEKNFHKSQHDYFDDPEGICDLTSRLLRNQDPNFVWVPTYN-----SLDSRL-LKN 142

  Fly   111 DQ-VINHFPNSIELSRKDL---------------------------------------------L 129
            || :|||:..|:..::..|                                             :
 Frog   143 DQIIINHYSKSVFTTKVGLCLNLRNLHWFADADLNSFFPRCYRLGVKEEKEAFIEDFRLTAACSI 207

  Fly   130 IKNIKRYRKDLERRGD------------------PLAQSHPPD--------TKLGIGGTRYKHLD 168
            :|.:.|..|::..|.|                  ||..|.|..        .|..:..:.:|.:|
 Frog   208 LKLVSREGKNMPNRRDVKKEITAALLLKYYKKAKPLITSVPVQIIKTALKACKQYLNTSEHKDID 272

  Fly   169 --IIPMTFVLPSDYQMFV----EVFHRN-------------------------------PASTWI 196
              :.....:...:::.|:    :..|:|                               ..:.||
 Frog   273 WKLGSTNAITEDEWKEFLHGYYQAIHKNIIINEAENYVSQCQDMLQKLKAVKPQLDIDGERNIWI 337

  Fly   197 VKPCSKSQGVGIYLVNKLSKLKKFAYDARTFYPQINRDTCVISKYIDNPLLIGGKKFDLRLFVLV 261
            |||.:.|:|.||..::.|.:..|:. |....:  ||.|..|:.|||:.||||.|.|||:|.:.:|
 Frog   338 VKPGASSRGRGITCIDYLEEALKYV-DCDPLF--INDDKLVVQKYIERPLLIYGTKFDVRQWFMV 399

  Fly   262 TTFNPLKAYLYKEGFCRFCTEKYDETEIDNVFMHLTNVSIQKTNQEYNSIHGGKWPLQNLWL--- 323
            |.:|||..:.|||.:.||.::.:....:.: .:||.|.::||..:...|.| .:.|.:|:|.
 Frog   400 TNWNPLTIWYYKECYLRFSSQPFSLKNLHS-SIHLCNNAVQKNYKISRSRH-PRLPKENMWFKNQ 462

  Fly   324 YLDSLRGEGVSDMLWSRI-----TATIRHSLDAVAPVMANDRHCFEVYGYDIIIDNNLKPWLIEI 383
            :.|.|:..|.:: .|..|     .|.|.|::.....:....::.|::||.|.:...|.:||||||
 Frog   463 FQDYLQMTGATN-AWKEIIEPGMKAAIIHTMQCSQDMEEGRKNSFQIYGADFMFGENFQPWLIEI 526

  Fly   384 NTSPSMHSTTTNDRMLKSRLIDNVLDVVVPPNCMPNEHWDKTPNPELLKNFTVLMPISPCKPKEQ 448
            |.:|.|..:|:....|..|:.:::|.:::          |:..:.:.   :..:..:...:|..:
 Frog   527 NANPDMSLSTSVTSRLVVRVQEDILRLIL----------DRKQDADA---YVGVFELIYKQPVIK 578

  Fly   449 VPV-RRKGRLSKKKKSKSTTASSGICS------FTPPPAEGE--------TKIKRSNKVVK 494
            :|: .||..|.|..:.|....:|.:.:      |....|:||        ||...:.|.:|
 Frog   579 IPLCERKQLLVKGNQIKKPLQTSPLMTDEKNQMFKGSIAKGERNPCLLHRTKTTATWKEIK 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TTLL1A	NP_573197.2	TTL	107..419	CDD:397308	96/428 (22%)
ttll3	XP_002941012.2	TTL	286..552	CDD:397308	76/271 (28%)