Protein Alignment baz and pard3

DIOPT Version :10

• Sequence 1: NP_001036283.1
• Gene: baz / 32703
• FlyBaseID: FBgn0000163
• Length: 1520
• Species: Drosophila melanogaster
• Sequence 2: XP_004915520.1
• Gene: pard3 / 733833
• XenbaseID: XB-GENE-490065
• Length: 1370
• Species: Xenopus tropicalis
• Alignment Length: 1617
• Identity: 419/1617 - (25%)
• Similarity: 610/1617 - (37%)
• Gaps: 514/1617 - (31%)

  Fly    62 PDSWVTVTHLQ-TQSGILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASGSSSVGTGS 125
            |..|:.|..|: ...||||.||.:.|||||:::::|.:|:..     |..||||.| :||.||.|
 Frog    42 PGYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAIYDEQD-----PHHGGDGTS-ASSTGTQS 100

  Fly   126 PDIFRDP--TNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKA------ 182
            |:||...  ||:.:...|...:: .||||.:    :....:.|.|||||||.|:....:
 Frog   101 PEIFGSELGTNSMSAFQPYQAAS-EIEVTPS----VLRANMPLHVRRSSDPALVGITTSVSDSNF 160

  Fly   183 ---EGSNK---RWSAAAPHYAGGDSPERLFLDK--AGGQLSPQWEEDDDPSHQLKEQLLHQQQPH 239
               |.|.|   |||..|.           |..|  :.|..:.:.::|::.....::.....:|..
 Frog   161 TSEEPSRKNPTRWSTTAG-----------FTKKNTSAGMGASEIKKDENYRSLPRDTSNWSKQFQ 214

  Fly   240 AANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAY 304
            ..|..||.....|...:               |:|..|  |::..|:
 Frog   215 RDNARSSLSASHPLVDT---------------WLERQE--QDEEEAE------------------ 244

  Fly   305 SSKSLPRESKRKEPLGQA------YESIREKDGEMLLIINEYGSPLGLTALPDKEHGG---GLLV 360
                   |:.|.||:|.|      ..|....|...|:.::..|.|||:..:|....||   ||||
 Frog   245 -------ENSRVEPVGHADTGLERTSSFSLDDMVKLVEVSNDGGPLGIHVVPYSARGGRTLGLLV 302

  Fly   361 QHVEPGSRAERGRL-RRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVRVL---------- 414
            :.:|.|.:|||..| ..:|.|:.||...|......|.|...|:|:.|..:...|:
 Frog   303 KRLEKGGKAERENLFHENDCIVRINNGDLRNRRFEQAQNMFRQAMRSPIIWFHVVPAANKEPYEQ 367

  Fly   415 --RGDRN----------------------------RRQQRDSKVAEMVE-----VATVSPTRKPH 444
              :.:.|                            :|..|.|..|:.::     ..:::...||
 Frog   368 LSQSENNSYYSSQHVHDSQYMDSRSFSSPGPDHTAQRMPRQSSQADPMDSYSHLPQSINSAGKP- 431

  Fly   445 AAPVG--TSLQVA---------NTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNIL 498
              |.|  ||.|.|         .|:| |:|..|.||||..|||||:|:||.|.||..|||:||||
 Frog   432 --PTGLTTSPQRAVSPPTNSAYGTKK-GKKFYIQLKKGAEGLGFSITSRDVPLGGSAPIYVKNIL 493

  Fly   499 PRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAE 563
            ||||||:|||:|.|||||||:|..:||:||.:||::||....|..|.::|.||.|...
 Frog   494 PRGAAIQDGRMKAGDRLLEVNGVDLTGRTQEEVVSLLRSTKMGGAVNLLVLRQDETFH------- 551

  Fly   564 KSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDS 628
                            |....|.|    .:.|:||...|.:::..|.
 Frog   552 ----------------PRELNPEP----SQVSNARETKTEEEELVLT------------------ 578

  Fly   629 LPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFV 693
              |..    :||.||..||::|:..|||||||||                 |...::..||||||
 Frog   579 --PDG----TREFLTFEIPLNDSGSAGLGVSVKG-----------------NRSKENHADLGIFV 620

  Fly   694 KNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKIL 758
            |::|:|||||:|||||:||||::|||.||.|:.|.:||||||::| :|.|...|.|.|:|.|:|.
 Frog   621 KSIINGGAASKDGRLRVNDQLVAVNGESLLGKTNQDAMETLRKSM-STEGNRRGMIQLIVARRIK 684

  Fly   759 RSASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGG 823
            ||                                 ...|..|.:.....|....:.||:|.:...
 Frog   685 RS---------------------------------ELESPGSPSGPELPIETMLDDRERRISHSL 716

  Fly   824 GGGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAAL 888
            ..|..|.:.:...|..|:|:.|              .:|..|..:..|
 Frog   717 YSGIEGFDESPTRNAALNRIMG--------------KYQLSPTVNMPQ----------------- 750

  Fly   889 RNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPAR--------PHDGQHCNTSSA 945
                                     :..::||||   .:|.|||:        .||...|.|.|.
 Frog   751 -------------------------DDTVIIEDD---RTPVLPAQLSDHSSSSSHDDVGCVTDST 787

  Fly   946 NP-SQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAA 1009
            :. |:.:|             :.||.|.........|:         |.|:..||:|:|||....
 Frog   788 SAWSKTVA-------------SESTESTLSPDMDPSLA---------FQREGFGRQSMSEKRTKQ 830

  Fly  1010 L-DARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIE 1073
            . ||.:....    |.|:.:..:.....||.:...|......:|
 Frog   831 FGDASQLDFV----KTRKSKSMDLVADETKISAMAGQNSGSPSR--------------------- 870

  Fly  1074 QRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMS-DEPRGHQALRAPRGRGR 1137
                                |:|||||:|||||||||||.|.|:.:: |.|......|..||||.
 Frog   871 --------------------DVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGC 915

  Fly  1138 EDSLRAAV---------------------VSEPDASKPRKTWLLEDGD----------------H 1165
            .:|.|||:                     .||.:.......|:.||.:                |
 Frog   916 NESFRAAIDKSYDKPSADDDDEGMETCTNKSELEPINSSSEWVEEDTEESSKSGRESVSTASDQH 980

  Fly  1166 EGGFASQRNGPFQSSLN-----DGKHGCK-----SSRAKKPSILRGIGHMFRFGKNRKDGVVPVD 1220
            ......|.||......:     .||...|     .::|||..:|:|:|.||:|||:|||.
 Frog   981 SHSLERQVNGSSHDKSDRKKDKSGKEKKKDRDKEKNKAKKGGMLKGLGDMFKFGKHRKDD----- 1040

  Fly  1221 NYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPN 1285
                .|....|....|......:.::.:::|.|::.|..|..|.  ||..:...|.........:
 Frog  1041 ----KIDHGGSWKMRAQEAHPSEDERMRMRQEQERIQAKTRELR--ERQAREKDYAEIQDYAKTH 1099

  Fly  1286 G----------------VGSNGIHQNDIFNHRYQ---HYANYEDLHQQHQQHQISGGDSTTSISE 1331
            |                ..|..:|    .|:|.|   .....|.|:.|.::.:.|......|...
 Frog  1100 GSLDESPYAGAGLYDTCTNSGTLH----LNNRPQSPRDAKQTEALYAQVKKPRSSKPSPVDSNRS 1160

  Fly  1332 TLS-ESTLECMRQQVIRQRIKVEAESRRHQHYHSQ---------RSARSQDVSMHSTSSGSQPGS 1386
            |.| ...::.:||:..:.|.:.:.:.||..:...|         :|.|      ||.|...|
 Frog  1161 TPSNHDRIQRLRQEFQQARQEDDVDERRRTYSFEQPWPNTPTYNQSGR------HSVSVEVQ--- 1216

  Fly  1387 LAQPQAQSNGVRPMSSYYEYETVQQQRVGSIKHSHSSSATSSSSSPINVPH--WKAAAMNGYSPA 1449
             .|.|.|.          |.|:.||     .:..:||....|..:|.:|..  |:.|    |.|.
 Frog  1217 -MQRQRQE----------ERESFQQ-----AQRQYSSLPRQSRKNPSSVSQDSWEQA----YPPG 1261

  Fly  1450 SLNSSARSRGPFVTQVTIREQSSG--GIPAHLLQQHQQQQLQQQQPTYQTVQKMSGP 1504
            ....||:....:.:....|....|  |..|.::.:.|:...|:|:...|.::|...|
 Frog  1262 EGFQSAKENPRYSSYQGSRNGYMGGHGFNARVMMETQELLRQEQRRKEQQLKKKVSP 1318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	Par3_HAL_N_term	<62..100	CDD:463446	16/38 (42%)
		PDZ1_PDZ3_bazooka-like	330..416	CDD:467154	30/101 (30%)
		PDZ2_Par3-like	459..551	CDD:467271	55/91 (60%)
		PDZ3_Par3-like	639..756	CDD:467272	59/116 (51%)
pard3	XP_004915520.1	Par3_HAL_N_term	2..83	CDD:463446	17/40 (43%)
		PDZ1_Par3-like	267..363	CDD:467178	30/95 (32%)
		PDZ2_Par3-like	454..546	CDD:467271	55/92 (60%)
		PDZ3_Par3-like	583..682	CDD:467272	59/116 (51%)