DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Slc9a3r2

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_075542.2	Gene:	Slc9a3r2 / 65962	MGIID:	1890662	Length:	337	Species:	Mus musculus

Alignment Length:	348	Identity:	81/348 - (23%)
Similarity:	139/348 - (39%)	Gaps:	71/348 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   322 AYESIREKDGEMLLIINEYGSPLGLTALPDKEHG----GGLLVQHVEPGSRAERGRLRRDDRILE 382
            |.||:|.:...::.....||..|         ||    .|..::.|||||.||...||..||::|
Mouse     3 ALESLRPRLCRLVRGEQGYGFHL---------HGEKGRRGQFIRRVEPGSPAEAAALRAGDRLVE 58

  Fly   383 INGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPH--- 444
            :||:.:.|.|..||.::::.....::|.|.....|....:::.:...||.. ..:.|...|.
Mouse    59 VNGVNVEGETHHQVVQRIKAVEGQTQLLVVDKETDEELCRRQLTCTEEMAH-RGLPPAHNPWEPK 122

  Fly   445 -----AAPVGTSLQVANTRKLGRKIE---IMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRG 501
                 :..:|:.....:.....|::.   ..|::||.|.||::.:..:..|.    ||:::.|..
Mouse   123 PDWACSGSLGSDTGQKDVNGPPRELRPRLCHLRRGPQGYGFNLHSDKSRPGQ----YIRSVDPGS 183

  Fly   502 AAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSA 566
            .|...| |:..|||:||:|..:.|....:|||.::.....|.:.:|       ..:.|:..::..
Mouse   184 PASHSG-LRAQDRLIEVNGQNVEGLRHAEVVARIKAQEDEARLLVV-------DPETDEHFKRLR 240

  Fly   567 GVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPP 631
            .:.....|..|.         |.||...:|         .:|||        |....:|...||.
Mouse   241 VIPTEEHVEGPL---------PSPVTNGTS---------PAQLN--------GGSVCSSRSDLPG 279

  Fly   632 S------SNSWHSR--EELTLHI 646
            |      .::|...  :|..||:
Mouse   280 SEKDNEDGSTWKRDPFQESGLHL 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492	24/74 (32%)
		CRS1_YhbY	<390..>436	CDD:294440	9/45 (20%)
		PDZ_signaling	462..548	CDD:238492	25/88 (28%)
		PDZ_signaling	<686..753	CDD:238492
Slc9a3r2	NP_075542.2	PDZ_signaling	9..88	CDD:238492	25/87 (29%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	112..147		4/34 (12%)
		PDZ	148..230	CDD:214570	25/93 (27%)
		EBP50_C	232..337	CDD:286142	19/97 (20%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	242..337		18/87 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810