DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Slc9a3r1

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_067605.1	Gene:	Slc9a3r1 / 59114	RGDID:	708538	Length:	356	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	91/348 - (26%)
Similarity:	133/348 - (38%)	Gaps:	85/348 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   338 NEYGSPLGLTALPDKEHGG----GLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQE 398
            |.||..|         ||.    |..::.|||||.||:..|...||::|:||..:...|..||..
  Rat    22 NGYGFHL---------HGEKGKVGQFIRLVEPGSPAEKSGLLAGDRLVEVNGENVEKETHQQVVS 77

  Fly   399 QLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRK 463
            ::|.||.:    ||:|..|....:|.......:.|....:..:..|..|..    .|:|:|.|.:
  Rat    78 RIRAALNA----VRLLVVDPETDEQLKKLGVPIREELLRAQEKSEHTEPPA----AADTKKAGDQ 134

  Fly   464 IE---------------IMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGD 513
            .|               ..:||||||.||::.:..:..|.    :|:.:.|...|...| |:..|
  Rat   135 NEAEKSHLERCELRPRLCTMKKGPNGYGFNLHSDKSKPGQ----FIRAVDPDSPAEASG-LRAQD 194

  Fly   514 RLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQEL---------AEQADQP-------- 561
            |::||:|..|.||...|||:.::.....|.:.:|.....|.         .|..|.|
  Rat   195 RIVEVNGVCMEGKQHGDVVSAIKAGGDEAKLLVVDKETDEFFKKCRVTPSQEHLDGPLPEPFSNG 259

  Fly   562 ---AEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESA 623
               .|.|....|.        ||:.:|.|.:....||..        ..:||        ..:|.
  Rat   260 EIQKENSREALVE--------PASESPRPALARSASSDT--------SEELN--------AQDSP 300

  Fly   624 ASNDSLPPSSNSWHSREELTLHI 646
            ..:||..|||.|..|...|..:|
  Rat   301 KRHDSTEPSSTSSSSDPILDFNI 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492	24/74 (32%)
		CRS1_YhbY	<390..>436	CDD:294440	12/45 (27%)
		PDZ_signaling	462..548	CDD:238492	27/100 (27%)
		PDZ_signaling	<686..753	CDD:238492
Slc9a3r1	NP_067605.1	PDZ_signaling	12..91	CDD:238492	29/81 (36%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	113..142		7/32 (22%)
		PDZ_signaling	149..228	CDD:238492	26/83 (31%)
		EBP50_C	232..356	CDD:286142	25/116 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	265..356		20/83 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810