DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Tamalin

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_062391.3	Gene:	Tamalin / 56149	MGIID:	1860303	Length:	392	Species:	Mus musculus

Alignment Length:	393	Identity:	72/393 - (18%)
Similarity:	118/393 - (30%)	Gaps:	140/393 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   550 RQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQH 614
            :|:|.|..|..||.::.....|.:...|:.|.|||..|..|.::..:|.            |..|
Mouse    10 QQKEEATAAPDPAGRAPDSEAARAAPLPSGPPAAAAPPGAPGEELYAAL------------EDYH 62

  Fly   615 FIDAGSESAASNDSLPPSSNS---W---------------------------------HSREE-- 641
            ..:.....|.|..:||....|   |                                 |.|||
Mouse    63 PAELYRALAVSGGTLPRRKGSGFRWKNFTQSPEQQRKVLTLEKGDNQTFGFEIQTYGLHHREEQR 127

  Fly   642 ---LTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIH----- 698
               :|....||::..|.|.....|.|.:::|                    |:.|:.:.|
Mouse   128 VEMVTFVCRVHESSPAQLAGLTPGDTIASVN--------------------GLNVEGIRHREIVD 172

  Fly   699 ----GGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTIT---LLVGRK 756
                .|...|         |.::.|.|:|.......::.|::.:....|::...:.   .||...
Mouse   173 IIKASGNVLR---------LETLYGTSIRKAELEARLQYLKQTLYEKWGEYRSLMVQEQRLVHGL 228

  Fly   757 ILRSASSSDILDHSNSHSHSHSNSSG-----------GSNSNGSGNNNNSSSNA----------- 799
            :::..|..|.|:...|..:......|           ||...|:......:.:|
Mouse   229 VVKDPSIYDTLESVRSCLYGAGLLPGSLPFGPLLAAPGSARGGARRAKGDTDDAVYHTCFFGGAE 293

  Fly   800 -----------------SDNSGATVIYLSP-----EKREQRCNGGGGGGSAGNEMNRWSNPVLDR 842
                             |..:.|:|::.:|     .....||.|.||||.|...:  |:......
Mouse   294 PQALPPPPPPARALGPSSAETPASVLFPAPRSTLSRSASVRCAGPGGGGGAPGAL--WTEAREQA 356

  Fly   843 LTG 845
            |.|
Mouse   357 LCG 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492
		CRS1_YhbY	<390..>436	CDD:294440
		PDZ_signaling	462..548	CDD:238492
		PDZ_signaling	<686..753	CDD:238492	11/78 (14%)
Tamalin	NP_062391.3	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50		13/39 (33%)
		PDZ_signaling	99..184	CDD:238492	17/113 (15%)
		Interaction with PSCD3. /evidence=ECO:0000269\|PubMed:10828067	180..257		14/85 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..315		1/20 (5%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900