DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Gopc

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001101101.2	Gene:	Gopc / 309774	RGDID:	1309512	Length:	463	Species:	Rattus norvegicus

Alignment Length:	515	Identity:	116/515 - (22%)
Similarity:	165/515 - (32%)	Gaps:	180/515 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 GPDPGVPQGGGDGASGSS---SVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLG 163
            ||   .|.|.|.|..|:|   .|..|...:||                 .:||.. .....|.:.
  Rat     5 GP---CPAGAGSGPGGASCPVGVSPGGVSMFR-----------------WLEVLE-KEFDKAFVD 48

  Fly   164 VGLMVRRSSDPNLLASLKAEGSNKRWSAAAPHYAGGDSPERLFLDKAGGQLSPQWEEDDDPSHQL 228
            |.|:: ...||: .|.:..||..|..|                |.....||..:.:.....:|:|
  Rat    49 VDLLL-GEIDPD-QADITYEGRQKMTS----------------LSSCFAQLCHKAQTVSQINHKL 95

  Fly   229 KEQL---------------------------LH--QQQPHAANGGS-SSGNHQPFARSGRLSMQF 263
            :.||                           ||  |.|.||..|.| .||     |...:||
  Rat    96 EAQLVDLRSELTETQAEKVVLEKEVHDQLLQLHSTQLQLHAKTGQSVDSG-----AIKAKLS--- 152

  Fly   264 LGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAYSSKSLPRESKRKEPLGQAYESIRE 328
                     :.:.|.|:.:..|.:|                        .|.||...:|...:..
  Rat   153 ---------VHSMEDLERELEANKT------------------------EKVKEARLEAEVKLLR 184

  Fly   329 KDGEML------LIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIK 387
            |:.|.|      |....||:.|....| |||..|  .||.::...|..:|....          |
  Rat   185 KENEALRRHIAVLQAEVYGARLAAKYL-DKELAG--RVQQIQLLGRDMKGPAHD----------K 236

  Fly   388 LIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVG--- 449
            |....|:::.      |...:..:|..||    ||.                .::|..||.|
  Rat   237 LWNQLEAEIH------LHRHKTVIRACRG----RQD----------------LKRPMQAPPGHDQ 275

  Fly   450 TSLQVANTRKLG--RKIEIMLKKGPNGLGFSVTTRDNPAGGH---CPIYIKNILPRGAAIEDGRL 509
            .||:  .::.:|  ||: ::||:...|||.|:|      ||.   .||.|..|.|...|...|.|
  Rat   276 DSLK--KSQGVGPIRKV-LLLKEDHEGLGISIT------GGKEHGVPILISEIHPGQPADRCGGL 331

  Fly   510 KPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIV-----VSRQQELAEQADQPAEK 564
            ..||.:|.|:|..:......:.|.||..........:|     |....|..|..|:...:
  Rat   332 HVGDAVLAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAPEVDSDDENVEYEDESGHR 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873	17/74 (23%)
		PDZ_signaling	341..412	CDD:238492	15/70 (21%)
		CRS1_YhbY	<390..>436	CDD:294440	7/45 (16%)
		PDZ_signaling	462..548	CDD:238492	28/93 (30%)
		PDZ_signaling	<686..753	CDD:238492
Gopc	NP_001101101.2	SMC_prok_B	<35..>215	CDD:274008	50/240 (21%)
Gopc	NP_001101101.2	PDZ_signaling	287..369	CDD:238492	27/88 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900