DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Cytip

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_631939.1	Gene:	Cytip / 227929	MGIID:	2183535	Length:	359	Species:	Mus musculus

Alignment Length:	334	Identity:	71/334 - (21%)
Similarity:	113/334 - (33%)	Gaps:	117/334 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   413 VLRG----DRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLG------RKIEIM 467
            ||.|    :.|||.|   .:|:  .|||:...||        .|.:|.:..||      ||: :.
Mouse    29 VLTGQLTMEDNRRIQ---VLAD--TVATLPRGRK--------QLALARSSSLGDFSWSQRKV-VT 79

  Fly   468 LKKGPNG-LGFSVTT---------------------RDNPAGGHCPIYIKNILPRGAAIEDGRLK 510
            ::|..|| .||.:.|                     .|:||  ||                ..|:
Mouse    80 VEKQDNGTFGFEIQTYRLQNQNICSSEVCTMICKVQEDSPA--HC----------------AGLQ 126

  Fly   511 PGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVR----IVVSRQQEL---AEQADQPAEKS--- 565
            .||....|:|....|.|...||.::|......|:.    .::.|:.||   .:...|..:|.
Mouse   127 VGDIFANVNGVSTEGFTHKQVVDLIRSSGNLLTIETLNGTMIHRRAELEAKLQTLKQTLKKKWVE 191

  Fly   566 -------------AGVAVAPSVAPPAVPAAA------APAPPI----PVQKSSSARSLFTHQQQS 607
                         ...|.:|::....:..::      .|:|.:    .:...||.:|..
Mouse   192 LRSLHLQEQRLLHGDTANSPNLENMDLDESSLFGNLLGPSPALLDRHRLSSESSCKSWL------ 250

  Fly   608 QLNESQHFIDA--GSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNA 670
                |...:|:  |..|:.|.||:..:.:...|.::...|        :..|..:.....|..|.
Mouse   251 ----SSLTVDSEDGYRSSMSEDSIRGAFSRQTSTDDECFH--------SKDGDEILRNASSRRNR 303

  Fly   671 SGSSASSGS 679
            |.|..||||
Mouse   304 SISVTSSGS 312

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492
		CRS1_YhbY	<390..>436	CDD:294440	9/26 (35%)
		PDZ_signaling	462..548	CDD:238492	24/111 (22%)
		PDZ_signaling	<686..753	CDD:238492
Cytip	NP_631939.1	PDZ_signaling	76..161	CDD:238492	23/103 (22%)
Cytip	NP_631939.1	Interaction with CYTH1. /evidence=ECO:0000250	166..188		4/21 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900