DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and Pdzd3

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_573489.2	Gene:	Pdzd3 / 170761	MGIID:	2429554	Length:	498	Species:	Mus musculus

Alignment Length:	452	Identity:	100/452 - (22%)
Similarity:	160/452 - (35%)	Gaps:	135/452 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   359 LVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRV------------ 411
            :|..|:||:.|:|..||..||||.:|.    .:...:....:.|.:.:|..||
Mouse    74 VVCRVDPGTSAQRQGLREGDRILAVNN----NIVAHEDHAVVVRYIRASGPRVLLTVLAQHVHDV 134

  Fly   412 -RVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGL 475
             |||:|..                |.:.||     .|.|...::.:           :.|...|.
Mouse   135 ARVLQGSD----------------AFLCPT-----LPSGVRPRLCH-----------VVKDEGGF 167

  Fly   476 GFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPA 540
            |||||     .|...|.::  :|..|.|.|...:.||.|||||:|..:...|...:...|  ..:
Mouse   168 GFSVT-----HGSRGPFWL--VLSAGGAAERAGVPPGARLLEVNGASVEKLTYNQLNRKL--WQS 223

  Fly   541 GATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPP--IPVQKSSSARSLFTH 603
            |..|.::|: ..|:.||..|         :...:|.|.....|.||.|  :.::|..........
Mouse   224 GDQVTLLVA-GLEVEEQCHQ---------LGMPLAAPLAEGWALPAKPRCLNIEKGPEGFGFLLR 278

  Fly   604 QQQ---SQLNESQHFIDAGSES------------AASNDS------------------------L 629
            :::   .:|.:....:|.|..:            |.:.:|                        :
Mouse   279 EEKGLDGRLGQFLWDVDPGLPADKAGMKAGDRLVAVAGESVDGLGHEETVSRIRAQGSCVSLIVV 343

  Fly   630 PPSSNSWHSREEL------------------TLHIPVHDT-EKAGLGVSVKGKTCSNLNASGSSA 675
            .|.::.:.|...|                  |..:||.|| |.:||..|     |......|...
Mouse   344 DPEADRFFSMVRLSPLLFLENTEIAAPPLAETKDLPVEDTVEPSGLAGS-----CQCFLYPGPGG 403

  Fly   676 SSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRA 737
            ..|........|.. :|:..|..||:|:|.| |::.|.:|.|||..:.|.:..:.::.|..|
Mouse   404 GYGFRLCCVASGPC-LFISQVTPGGSAARAG-LQVGDTVLEVNGYPVGGDSELDRLQQLTEA 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492	17/65 (26%)
		CRS1_YhbY	<390..>436	CDD:294440	8/58 (14%)
		PDZ_signaling	462..548	CDD:238492	25/85 (29%)
		PDZ_signaling	<686..753	CDD:238492	17/52 (33%)
Pdzd3	NP_573489.2	PDZ_signaling	47..127	CDD:238492	17/56 (30%)
		PDZ_signaling	155..232	CDD:238492	25/96 (26%)
		PDZ	260..345	CDD:214570	7/84 (8%)
		PDZ_signaling	407..471	CDD:238492	17/59 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810