Protein Alignment baz and baz

DIOPT Version :10

• Sequence 1: NP_001036283.1
• Gene: baz / 32703
• FlyBaseID: FBgn0000163
• Length: 1520
• Species: Drosophila melanogaster
• Sequence 2: XP_316842.6
• Gene: baz / 1277384
• VectorBaseID: AGAMI1_007445
• Length: 1862
• Species: Anopheles gambiae
• Alignment Length: 1959
• Identity: 798/1959 - (40%)
• Similarity: 981/1959 - (50%)
• Gaps: 592/1959 - (30%)

  Fly     1 MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQ--LHKSYSLTLPKR------------- 50
            :|::||||||||||:.|:|||||||:|..:|:|||||.  |:|||||.||::
Mosquito     7 IFELPPKCPALANKITGIFGWRHTYQVHQRQKGIPHGNQYLYKSYSLNLPRKVGGSCETLDSGGS 71

  Fly    51 -----------------------------PPSPSTYSCV--------------KPDSWVTVTHLQ 72
                                         |.|.|:.||.              .|||||.|.|||
Mosquito    72 SGTLEAGGSGGARSASSSTRGLTSAYRQQPASSSSNSCCTTLEPGTAAPCCAKNPDSWVVVHHLQ 136

  Fly    73 TQSGILDPDDCVRDVADDREQILAHFDDP--GPDPGVPQGGGDGASGSSSVGTGSPDIFRDP--- 132
            :|||||||:|.:.|||||||:|:|.::|.  |.||||.||||||||| |||||||||||:.|
Mosquito   137 SQSGILDPEDHISDVADDREEIIASYEDAAVGLDPGVQQGGGDGASG-SSVGTGSPDIFQTPGGG 200

  Fly   133 -----------TNTEAPTCPRDLSTPHIEVT------------------------STTSGPMAG- 161
                       .....|....|.|...:.|.                        .:.|||..|
Mosquito   201 GKVPPLGGGVVVGVGGPAPLADGSGGPVVVVGAGGSGAPGSGGSAADSVVVTVGGGSESGPGGGA 265

  Fly   162 ------------LGVGLMVRRSSDPNL-----------LASLKAEG----SNKRWSAAAPHYAGG 199
                        ||:||.|||.|:|:|           |.::...|    ::||||||....:..
Mosquito   266 SCIEVFANEPAPLGLGLQVRRGSEPSLHQIGVTEQRSPLYNVNPNGNHQSTSKRWSAAPVCRSDS 330

  Fly   200 D-SPERLFLDKAGG-----------------------QLSPQWE--EDDDPSHQLKEQLLHQQQP 238
            | .|:||...:..|                       .|..:|.  |:|....|.:.|...|||.
Mosquito   331 DPPPDRLLSPQQNGGGGGPPYHYHHNHHHHHNPHHHHLLGEEWNVPEEDSGQQQQQHQQQQQQQQ 395

  Fly   239 HAANGGSSSGNHQPFARSGRLSMQFLG--DGNGYKWMEAAEK----------------------- 278
            |      .|...|.|.|||||||||||  ...||:||:||||
Mosquito   396 H------DSLLPQAFNRSGRLSMQFLGAEASTGYRWMDAAEKAAAAAAAATATTPSSSASSSAAH 454

  Fly   279 ---------------LQNQPPAQQTYQQGSHHA------GHGQNGAYSSKSLPRESKRKEPLGQA 322
                           :|.|...||..|..|.||      |.|.|.::|||||||||.||||||||
Mosquito   455 NQSSPAYGYQTYQNYVQQQQQQQQQMQHHSFHAGSESVMGRGGNSSFSSKSLPRESTRKEPLGQA 519

  Fly   323 ----YESIREKDGEMLLIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEI 383
                |:||||||.||||::||.|.||||||:||.|. ||||||.|||||||||||:||.||||||
Mosquito   520 KASVYDSIREKDSEMLLVVNETGGPLGLTAIPDMER-GGLLVQSVEPGSRAERGRVRRGDRILEI 583

  Fly   384 NGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRN---------------------------RR 421
            |.|||:||:||.|||.|:::|.|:|||:||:||..:                           .|
Mosquito   584 NNIKLVGLSESSVQEHLKKSLASTELRLRVVRGGSSGGGGSVGGGSSGRAAGGGGRLLKSGSGPR 648

  Fly   422 QQRDSKVAEMV-----------EVATVSPTRK-PHAAPVGTSLQVANTRKLGRKIEIMLKKGPNG 474
            ..||::|.:|:           :||||||||| |.|...|||||||||||||::|||.|.||.:|
Mosquito   649 YPRDNRVGQMMIEAEEKPTSAAKVATVSPTRKIPGAPSTGTSLQVANTRKLGKRIEITLTKGDHG 713

  Fly   475 LGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMP 539
            |||||||||||||||||||||||||:|||:||||||||||||||:|.|||||:||:||:||||.|
Mosquito   714 LGFSVTTRDNPAGGHCPIYIKNILPKGAAVEDGRLKPGDRLLEVEGIPMTGKSQTEVVSILRGTP 778

  Fly   540 AGATVRIVVSRQQELAEQADQPAEKSAGVAV-------APSVAPPAVP----------------- 580
            .|||::||||||||||...   .|:..|.:|       .|...||.:|
Mosquito   779 HGATLKIVVSRQQELAADV---KEREIGFSVESEPKNSPPKPPPPVMPKSSLKQSNSSNSLAYGD 840

  Fly   581 -----------------------AAAAPAPPIP-VQK---SSSARSLFTHQQQSQLNESQHFIDA 618
                                   ||||.:|..| |||   :|..:|..|......|:|:......
Mosquito   841 GTDGSRTGVGNCRSLPKLAGGPGAAAAGSPKTPSVQKKPLASILKSASTTHVAELLHENGGSGRG 905

  Fly   619 GSE----SAASNDSLPPSSNS-------WHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASG 672
            |..    |.|||.|......|       |.:||.|||||||||||||||||||||||     .||
Mosquito   906 GGNVSNGSVASNASSGGGGGSESLAGAAWKNREILTLHIPVHDTEKAGLGVSVKGKT-----GSG 965

  Fly   673 SSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRA 737
            :.:||.|:|..:.|||||||||:|:|||||||||||:|||||||||||||.||:|||||:|||||
Mosquito   966 NGSSSSSSGTSRTDGDLGIFVKSVLHGGAASRDGRLKMNDQLLSVNGVSLLGQSNAEAMDTLRRA 1030

  Fly   738 MVNTPGKHPGTITLLVGRKILRSASSSDILDHSNSHSHSHSNSSGGSNSN----GSGNNNNSSSN 798
            |:.:.|.:||.|.|.:.|:|.|..|:.::|:.....:.:.:.::|.|..:    |.|
Mosquito  1031 MLQSGGSYPGKIILKIARRIGRPVSTGELLETMEQRTAAAAAAAGSSGEDQQPVGGG-------- 1087

  Fly   799 ASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEM-----NRWSNPVLDRLTGGIC---------- 848
               :||.||||||.:|:.|:.....|....|.:.     .|:|||||||||||..
Mosquito  1088 ---SSGTTVIYLSSDKQSQQSATSTGQHQTGGQQQQQSSKRYSNPVLDRLTGGSSANSTGTLHHT 1149

  Fly   849 -------------------------SSNSAQPSSQQSHQQQPH-----PSQQQQQQRRLPAAPV- 882
                                     ||.::..|:..|.|||.|     .:|:|..||...|.|:
Mosquito  1150 GSLPLSGGSGGGSSDTLTGGHYIRNSSTNSSTSTMSSQQQQQHHHSSNNNQRQSGQRSYGAPPMG 1214

  Fly   883 -CSSAA-------LRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQH 939
             .||||       ||||||||||.|:||... ...:.:|:..:|||:|.||.|||.    |..:.
Mosquito  1215 QPSSAAATTTPHGLRNESYYMATKDHWSTTS-SATSLNGSNVVLIEEDPEPTSPTF----HITRS 1274

  Fly   940 CNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETN-SGVEHFSRDALGRRSIS 1003
            ...::..||..: :||         |..||.:..||||:|||||||| ...:.|||||:||||:|
Mosquito  1275 LEGTAGGPSGGV-LGN---------GNTSTPNGADATYASQLSLETNPPPSDAFSRDAIGRRSMS 1329

  Fly  1004 EKHHAALDARETGTYQRNKKLREERERERRIQLTKSAV--YGGSIESL----TARIASANAQFSG 1062
            ||||||:||||||||||||||||:|:|:.::.::.|..  .|||:||:    .||:.|...|
Mosquito  1330 EKHHAAMDARETGTYQRNKKLREKRDRDSKLLMSGSGTSGAGGSLESIDLHHMARMNSLKQQ--- 1391

  Fly  1063 YKHAKTASSIEQRETQQQLAA--AEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRG 1125
            ..|.......|.:.|...|||  ..|||:|||||||||||||||||||||||||||:||:|||||
Mosquito  1392 QHHHHQQHHGEGKTTTAALAAHLLRAEAQDQLGDLGPSLGMKKSSSLESLQTMVQEIQMADEPRG 1456

  Fly  1126 HQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGD---------HEGGFASQRNGPFQSSL 1181
            ..|||.|||||||:.|| |||.:|..::.:|.||||||.         .:|||.| ||.||||||
Mosquito  1457 PNALRTPRGRGREEILR-AVVEQPAETQAKKHWLLEDGPAGGGAPGEFPDGGFVS-RNSPFQSSL 1519

  Fly  1182 NDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNY--------AVNISPPTSVVSTATS 1238
            ||||.|.|....|...:||||||||||||:|||.:||....        |::.:.|::::..|..
Mosquito  1520 NDGKGGAKLRAKKSGGLLRGIGHMFRFGKHRKDVIVPTGTITSTAPGEPAIDYTGPSTLLPPAPP 1584

  Fly  1239 P------------------------QLQQQQQQQLQQHQQQQQIPTAALAA------------LE 1267
            |                        .:.::....|..........|:|.||            :|
Mosquito  1585 PASGGMADSGGGGQKSSSGGGGSSNTISKRAAVALNSSGGNSSSATSAAAAAASRYVVYDPSSVE 1649

  Fly  1268 R---------NGKPPAYQ-PPPPLPAPNGVGSNGIHQNDIFNHRYQHYANYEDLHQQHQQHQISG 1322
            |         :.:||.|| ||||.||..|.....||..|:|||||.||.|||:|.||
Mosquito  1650 RSASSGVVYGHSQPPHYQPPPPPPPASGGPPGTSIHHTDVFNHRYSHYVNYEELQQQ-------- 1706

  Fly  1323 GDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSL 1387
                                            .||||..||||||||:....|....|    .|:
Mosquito  1707 --------------------------------ISRRHHLYHSQRSARNTPPMMDMGLS----ASI 1735

  Fly  1388 AQPQAQSNGVRPMSSYYEYETVQQQRVGSIKHSHSSSATSS------SSSPINVPH----WKAAA 1442
            ||.|.|             :..|||:....||.||||..||      ||.|::..|    ::..:
Mosquito  1736 AQQQQQ-------------QQQQQQQQQQQKHLHSSSTLSSQQGKYKSSRPVSSQHDGGGYETIS 1787

  Fly  1443 MNGYSPASLNSSA--------------------------------------------RSRGPFVT 1463
            ..| .|:|.:||.                                            ..||||||
Mosquito  1788 TTG-PPSSSSSSVHHRKEPSTSSSGGGGAGPTNEDSGTNGGEWHSHPGATGAGGSIRNMRGPFVT 1851

  Fly  1464 QVTIREQSS 1472
            ||.|:.|.|
Mosquito  1852 QVKIQNQLS 1860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	Par3_HAL_N_term	<62..100	CDD:463446	26/37 (70%)
		PDZ1_PDZ3_bazooka-like	330..416	CDD:467154	61/85 (72%)
		PDZ2_Par3-like	459..551	CDD:467271	74/91 (81%)
		PDZ3_Par3-like	639..756	CDD:467272	83/116 (72%)
baz	XP_316842.6	None