DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment baz and cytip

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	XP_003199223.2	Gene:	cytip / 100537036	ZFINID:	ZDB-GENE-140106-76	Length:	343	Species:	Danio rerio

Alignment Length:	402	Identity:	75/402 - (18%)
Similarity:	133/402 - (33%)	Gaps:	129/402 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   300 QNGAYSSKSLPRESKRKEPLGQAYES-------------------IREKDGEML-LIINEYGSPL 344
            |....|.|:|..|..:...|.|:..:                   :.::|.|:. ..:..||..:
Zfish    36 QRSFSSPKNLNTEGMKGRTLSQSQLARTHSNSLVDYTDPQRTMVVLEKQDNEVFGFEVQTYGLKV 100

  Fly   345 GLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSEL 409
            ..|::.:.    ...|..|:.||.||...|...|.||.:||:.:.|.|...:.|.:|.:  |:.|
Zfish   101 KNTSMVEM----CTFVCRVQDGSAAETAGLTAGDIILSVNGVSIEGSTHQNIIELIRES--SNTL 159

  Fly   410 RVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRK-IEIMLKKGPN 473
            ::..:.|...:|.:.:.|:..:.:.                         |..| :|:.
Zfish   160 KLETVSGSVMKRIELEKKMHYLKQT-------------------------LREKWVELQ------ 193

  Fly   474 GLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVD-----GTPMTGKTQTDVVA 533
                |:|.::.                  .:..|.|....:.|.||     .:||....|.
Zfish   194 ----SLTLKEK------------------RLTQGNLNESAQYLSVDSVMSLSSPMGRSGQR---- 232

  Fly   534 ILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSAR 598
                ..:.::.|.:::             :.|...|...||...:.|.:       |::.|.|..
Zfish   233 ----FSSDSSCRSIMT-------------DDSEDGAFMSSVFDDSSPLS-------PIESSGSFF 273

  Fly   599 SL-------FTHQQQSQLNESQHFIDAGSESAASN--DSLPPSSNSWHSREELTLHIPVHDTEKA 654
            .|       .|..:...|..|...:..|.|::.|:  .:||..|.....|:.|...||
Zfish   274 QLEVGALRPITRTRSISLTGSNSSLSPGWETSPSSLFGTLPRRSRKGSVRKHLLKFIP------- 331

  Fly   655 GLGVSVKGKTCS 666
            ||..||:.:.||
Zfish   332 GLNHSVEEEECS 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492	20/70 (29%)
		CRS1_YhbY	<390..>436	CDD:294440	9/45 (20%)
		PDZ_signaling	462..548	CDD:238492	13/91 (14%)
		PDZ_signaling	<686..753	CDD:238492
cytip	XP_003199223.2	PDZ_signaling	78..162	CDD:238492	23/89 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900