DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment baz and SYNJ2BP-COX16

DIOPT Version :9

Sequence 1:	NP_001036283.1	Gene:	baz / 32703	FlyBaseID:	FBgn0000163	Length:	1520	Species:	Drosophila melanogaster
Sequence 2:	NP_001189476.1	Gene:	SYNJ2BP-COX16 / 100529257	HGNCID:	48350	Length:	191	Species:	Homo sapiens

Alignment Length:	166	Identity:	44/166 - (26%)
Similarity:	67/166 - (40%)	Gaps:	22/166 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   465 EIMLKKGPNGLGFSVT--TRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKT 527
            ||.|.:||:||||::.  |..........||:..|...|||..||||:.||::|.|:|..:....
Human    13 EINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDKILSVNGQDLKNLL 77

  Fly   528 QTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQ 592
            ..|.|.:.|......::|:    |..|..|......:..|       .|..:|......|..
Human    78 HQDAVDLFRNAGYAVSLRV----QHRLQVQNGPIGHRGEG-------DPSGIPIFMVLVPVF--- 128

  Fly   593 KSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDS 628
                |.::...:.:.:|.|::  |...||.....||
Human   129 ----ALTMMDPELEKKLKENK--ISLESEYEKIKDS 158

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	DUF3534	<62..174	CDD:288873
		PDZ_signaling	341..412	CDD:238492
		CRS1_YhbY	<390..>436	CDD:294440
		PDZ_signaling	462..548	CDD:238492	29/84 (35%)
		PDZ_signaling	<686..753	CDD:238492
SYNJ2BP-COX16	NP_001189476.1	PDZ_signaling	13..97	CDD:238492	29/87 (33%)
		DegQ	<16..77	CDD:223343	23/60 (38%)
		COX16	<133..173	CDD:290843	7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900