Protein Alignment baz and pard3ba

DIOPT Version :10

• Sequence 1: NP_001036283.1
• Gene: baz / 32703
• FlyBaseID: FBgn0000163
• Length: 1520
• Species: Drosophila melanogaster
• Sequence 2: XP_017211256.1
• Gene: pard3ba / 100149472
• ZFINID: ZDB-GENE-080225-12
• Length: 1199
• Species: Danio rerio
• Alignment Length: 1603
• Identity: 360/1603 - (22%)
• Similarity: 543/1603 - (33%)
• Gaps: 616/1603 - (38%)

  Fly    66 VTVTHLQ-TQSGILDPDDCVRDVADDREQILAHFD----------DPGPDPGVPQGGGDGASGSS 119
            |...|:: ...|||||||.:.|:.:|:|::.|.|:          .||              ||.
Zfish    45 VRTLHVEYVDGGILDPDDMLSDLVEDKEKLTAVFEKLELQQRALVSPG--------------GSF 95

  Fly   120 SVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNL-----LAS 179
            :.|..|||......|...|....::......:.|||.         |.||.||||.|     ..|
Zfish    96 ASGRSSPDHSEPELNILHPYLSSEIEVTPSALKSTTP---------LSVRSSSDPALAPPLDAIS 151

  Fly   180 LKAEGSNKRWS--AAAPHYAGGDSPERLFLDKAGGQLSPQWEEDDDPSHQLKEQLLHQQQPHAAN 242
            |.:|.|::..|  .|.|....|.:.::|.:|..
Zfish   152 LDSEDSSRPQSTGVAPPVTVKGGAMDKLKVDNL-------------------------------- 184

  Fly   243 GGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAYSSK 307
               .|.|.|...||...:::..||                               ||
Zfish   185 ---ISRNGQDTLRSLTRTVEISGD-------------------------------HG-------- 207

  Fly   308 SLPRESKRKEPLGQAYESIREKDGEMLLIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERG 372
                      |||              :.:..|.|.|....|       ||.::.:|..||:||.
Zfish   208 ----------PLG--------------IKVIPYCSSLSGRTL-------GLNIRAIEKNSRSERE 241

  Fly   373 RL-RRDDRILEINGIKLIGLTESQVQEQLRRALESSE---LRVRVLRGDRNRRQQRD-------- 425
            :: ..|:.|::||..:||..:.:|.||..|:|:.||.   :.:.||......|.::.
Zfish   242 KIFEEDECIVQINDAELIDKSFAQSQEVFRQAMSSSSTSTVHLEVLPVANKLRYEKSLIGQLFNS 306

  Fly   426 -------------SKVAEMVEVATVSPTRKPHAA-----------------------------PV 448
                         ..|.::....|.:|:.:|.|:                             ||
Zfish   307 TETNPAVPKIKSPFLVRKLTPSNTATPSPEPAASQTPPIKEEELQRARHTPVELNHQSSTPSPPV 371

  Fly   449 GTSLQVAN--------------TRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILP 499
            .||..:.:              |:|.|:::.|.||||..||||:|.|||:...|..||.:|:|||
Zfish   372 STSPTLRDHSESPALASVVHMVTKKAGKRMRIDLKKGTEGLGFTVVTRDSSLHGPGPIMVKSILP 436

  Fly   500 RGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEK 564
            ||||::|||||.|||:|||:|..:||:||.::||:||....|.||.::|.||:|..     |.|
Zfish   437 RGAAVKDGRLKSGDRILEVNGVDITGRTQEELVAMLRSTKLGETVSLIVGRQEEFL-----PRE- 495

  Fly   565 SAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSL 629
                 :...|:.|.|                                             |.|
Zfish   496 -----LKGEVSGPLV---------------------------------------------SED-- 508

  Fly   630 PPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVK 694
                    .||:|...:|::|:..||||||:||         ..|..:|.        |||||:|
Zfish   509 --------GREQLMFEVPLNDSGSAGLGVSLKG---------NKSRETGE--------DLGIFIK 548

  Fly   695 NVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILR 759
            ::||||||::|||||:||||::||..||.|::|.:||||||.:| :|.|...|||.|:|.|.:.|
Zfish   549 SIIHGGAANKDGRLRVNDQLIAVNSESLVGRSNHDAMETLRHSM-STEGNLRGTIQLVVLRSLER 612

  Fly   760 SASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGGG 824
            |.:.                           .|..:|.:|
Zfish   613 SPAQ---------------------------ENYEASQSA------------------------- 625

  Fly   825 GGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALR 889
                    ||..:|||.|                  |...|:.:                   ..
Zfish   626 --------NRNDSPVLRR------------------HHHHPNSN-------------------TT 645

  Fly   890 NESYYMATNDNWSPAQMHLMTAHGNTALLI-----EDDAEPMSPTLPARPHDGQHCNTSSANPSQ 949
            |.|...:|.:..:||...   .||....|:     |||..|                     |..
Zfish   646 NNSVPQSTVNESAPAPYR---PHGGRPELLEVDYGEDDFPP---------------------PPS 686

  Fly   950 NLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARE 1014
            :|.:....||....|..|....      .||:|..||.
Zfish   687 DLDLLETNPPHKHQPNRPEMEP------FSQVSHPTNQ--------------------------- 718

  Fly  1015 TGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQ 1079
              .|.:.:|..|                                    |...||:.|::....:.
Zfish   719 --QYPQRQKAPE------------------------------------YSTNKTSKSMDLVADES 745

  Fly  1080 QLAAAEAEARDQLGD----LGPSLGMKKSSSLESLQTMVQELQMSD----EPRGHQALRAPRGRG 1136
            .:|:.:.:..:.:..    |||.||::||||||||||.::|:...:    .||.|..    ||||
Zfish   746 NMASIQGQRPEPISSNGTALGPRLGLRKSSSLESLQTAMEEVSKDEVPFHRPRAHMV----RGRG 806

  Fly  1137 REDSLRAAVVSEPDASKPRKTWLLEDGDHEGGFASQRNGPFQSSL-----NDGKHGCKSSRAKKP 1196
            ...|.|.|:  :.....|.:.   ||.|.|..  |.|:.|..||.     ||.|...|.::.||.
Zfish   807 CNMSFRYAI--DKSYEGPSEA---EDDDSEED--SGRDTPASSSSRQELDNDRKVKKKKTKKKKE 864

  Fly  1197 SILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQ------------- 1248
            ...:           :||.....|....  .....::|..|||.|:..|:..
Zfish   865 KKTK-----------KKDEAEDPDKKTK--KKGFGLLSMETSPDLRSVQKNMFGRKNKEDKTKSK 916

  Fly  1249 ------LQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNGIHQNDIFNHRYQHYAN 1307
                  :.:.:..:..|...|:..|||.           |||..|....:..:|: :..|....|
Zfish   917 AKQMVAVSEEEVDKSEPELFLSKSERNS-----------PAPERVIFPDVEDDDL-DPNYARINN 969

  Fly  1308 YEDLHQQHQQHQISGGDSTTSIS---------ETLSESTLECMRQQVIRQRI---KVEAESRRHQ 1360
            :.: .....|..:..|..|.:.:         |..:|..||.:..:|.:||.   |.|:...|.|
Zfish   970 FRN-PPASSQSPLPPGAPTNNYAQPAVPAPSREPPNEDALEGLYAKVNKQRTAPPKTESNEERLQ 1033

  Fly  1361 HYHSQ----RSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYE----YETVQQQRVGSI 1417
            ...:|    |.|.|.:...........|..:..|.:     |....|.:    |.:|.:::.
Zfish  1034 QIRNQLQQIRPAPSYEDLTARRRPEYDPSRIRGPDS-----RTAPRYNDADRLYTSVPRKKP--- 1090

  Fly  1418 KHSHSSSATSSSSSPINVPHWKAAAMNGYSPASLNSSARSRGPFVTQVTIREQSSGGIPAHLLQQ 1482
            ...:.:...|:...|:..|          :|...|.....|.| |.:.|  |......|:...:|
Zfish  1091 VDEYPNQNWSNQRDPVLYP----------NPIYDNPPRSPRLP-VPKPT--ETPGAHYPSSPAKQ 1142

  Fly  1483 HQQQQL-------QQQQPTYQTVQ----KMSGPSQYGSAAGSQ 1514
            ..:|.:       .::.|.|:.:.    :.:.|.:|......|
Zfish  1143 MMRQDVPPSSNPGAREPPRYEALNQGNYRTASPDRYSPYTDEQ 1185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
baz	NP_001036283.1	Par3_HAL_N_term	<62..100	CDD:463446	14/44 (32%)
		PDZ1_PDZ3_bazooka-like	330..416	CDD:467154	26/89 (29%)
		PDZ2_Par3-like	459..551	CDD:467271	50/91 (55%)
		PDZ3_Par3-like	639..756	CDD:467272	56/116 (48%)
pard3ba	XP_017211256.1	Par3_HAL_N_term	2..79	CDD:463446	13/33 (39%)
		PDZ1_Par3-like	193..292	CDD:467178	35/168 (21%)
		PDZ2_Par3-like	396..488	CDD:467271	50/91 (55%)
		PDZ3_Par3-like	510..608	CDD:467272	56/115 (49%)
		PHA03247	<959..1161	CDD:223021	40/224 (18%)