Protein Alignment Chchd2 and CHCHD2

DIOPT Version :10

• Sequence 1: NP_573196.1
• Gene: Chchd2 / 32701
• FlyBaseID: FBgn0260747
• Length: 170
• Species: Drosophila melanogaster
• Sequence 2: NP_001307256.1
• Gene: CHCHD2 / 51142
• HGNCID: 21645
• Length: 168
• Species: Homo sapiens
• Alignment Length: 170
• Identity: 85/170 - (50%)
• Similarity: 99/170 - (58%)
• Gaps: 31/170 - (18%)

  Fly     1 MVRRGRSASPPPSTRRTAPVQARAP----APAPAPVQTRAPAPAASAPVPAPMSAPPSAVG--MP 59
            |.|..||     .|.|.||..:|||    ||.||||   |..|||         |||||||  ..
Human     1 MPRGSRS-----RTSRMAPPASRAPQMRAAPRPAPV---AQPPAA---------APPSAVGSSAA 48

  Fly    60 APQQPSMFQQMAATAGGVAVGSAIGHTVGHGLTSLFSGSGDKEAAAPAPAAAAPAPQQPYYAQQQ 124
            ||:||.:..|||.||.|||||||:|||:||.:|..|||..:.|.|.|......|...||  ||||
Human    49 APRQPGLMAQMATTAAGVAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQP--AQQQ 111

  Fly   125 QPNEPQGACAWELKQFIQCAQGQADLTLCEGFNEALRQCK 164
            ||      |.:|:|||::|||.|.|:.|||||||.|:||:
Human   112 QP------CLYEIKQFLECAQNQGDIKLCEGFNEVLKQCR 145

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Chchd2	NP_573196.1	CHCH	133..165	CDD:429096	20/32 (63%)
CHCHD2	NP_001307256.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		28/65 (43%)
		COG3416	<4..>93	CDD:442642	52/105 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..111		14/35 (40%)
		Cx9C motif 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	114..124		5/9 (56%)
		Cx9C motif 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	134..144		7/9 (78%)