Protein Alignment CG5004 and Phldb2

DIOPT Version :9

• Sequence 1: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Sequence 2: XP_038944805.1
• Gene: Phldb2 / 685611
• RGDID: 1591402
• Length: 1358
• Species: Rattus norvegicus
• Alignment Length: 1461
• Identity: 313/1461 - (21%)
• Similarity: 516/1461 - (35%)
• Gaps: 438/1461 - (29%)

  Fly     4 TKKDPSLRVAA--SDPHLVSLGGGR---------LSTAVTIHYIHIGDTTIGSAASCSISLNGSG 57
            ||:.||...::  |.|.|..:.||:         :|....|.::           |.:.||:|..
  Rat   109 TKRSPSPLGSSVRSSPSLAKIQGGKQFCDGIDKNISMKPPISFL-----------SSTASLSGYP 162

  Fly    58 VRPLHCTIYRS-DANEVTLVPEK-------------DSRLLIDGAPILEETKLSQGAMITIGNSN 108
            :.......|.. |:.....:.||             ||...:.||    |.:.:.|:::|:.|.|
  Rat   163 IGKADLDHYTGRDSERSFRLSEKPPYSRYSSRNKSHDSVYFLGGA----EGRKASGSLLTMWNGN 223

  Fly   109 YLRFNNPDEAQMMRSAMGSNERISMPQIDFTQSARQAHE--LSQSLEL--------ESFYESII- 162
            .|  :....|.:.||...     |||     .|.:||.:  |..:|.|        |...|::.
  Rat   224 SL--SGTGSAPISRSGAA-----SMP-----SSPKQARKMNLQDNLPLQPRLSRHKEQASENVSV 276

  Fly   163 -------NPINNPSTYELECPKVF---SSDLVTVNMPAKDVLGQKYASFARNLAENHRNEKQLNN 217
                   :.::|...|....|:::   .:.:..:::|.::.||        |.......||.|.:
  Rat   277 RTRKYSGSSLSNMGAYSRSLPRLYKATDNQMSPLSLPPRNSLG--------NSRRGQLGEKDLPH 333

  Fly   218 QYAKGVGSNGGYWN---VPSNAAIYK------EQHQQQHQQAPQD-------LLTKVNNDRYDRY 266
            ...    .|..|.|   :.|.|:.||      ..:.......|..       ||...::|.:||.
  Rat   334 SLV----DNDNYLNFSSLSSGASPYKTCLSDGNPYVSSALSVPASPRVARKMLLASTSSDDFDRA 394

  Fly   267 PKAGGLQIYS-MNGVNSDINNGPATGNNSGTGGGAELEDMLKICTEYADRNNSMPSTHNVSSTSS 330
            ..:|....:| ::|....:    .....:.:.|..||:|            :.:.|...    ||
  Rat   395 SYSGTSPSHSFLSGEPDRV----LVARRNFSCGSMELDD------------SDLESLRQ----SS 439

  Fly   331 ITSSPIVQNRIKTNGSLP-----------------RDKNKSPFPQQAGVASSANISLLSSSSGYE 378
            .|..||::.|..:..|:.                 |::......:|   .....:||.:..:..|
  Rat   440 ETPQPILRERKSSISSISGRDDLMDYHRRQREERLREQEMERLERQ---RLETILSLCAEYTKPE 501

  Fly   379 NVRLLGPNRVEINGQIHVPASAGDGGSSSGVSSNAL-APTAAVRASHENLNQN----------HS 432
            ..||.....|....:|:.............|...|| .|.|..|...:...|:          ||
  Rat   502 GRRLSAGTTVADVQKINKELEKLQLSDEESVFEEALVCPDARYRCHRKGSLQDVDIAGFGSLGHS 566

  Fly   433 ATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIPSMVKPPLA 497
            |:.      .:||        ..|.|...|:   |...|||.:::.:.:|::...:      .:.
  Rat   567 ASF------LAPR--------GSKNDELLGD---LTRMPPPSSAAFLKATNESSYL------SIL 608

  Fly   498 PKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKPSRKPAPA 562
            ||.|....:          |::.|:|..|..|:....|      ||:.:|.:.:....
  Rat   609 PKTPEDMGE----------EQRTQELAAMEDARMVILN------NLEELEQKIKDIND------- 650

  Fly   563 PRSIHLEQRQRRELIQRRKQLKRELAELPPSAGIEGLELKLGEQPLAPSASPRLQLQALQNRVCR 627
                        ::.:..::|..|.|.|......|..|| :.|:.:         |..|..::..
  Rat   651 ------------QMDESSRELDMECALLDGEQKSETAEL-MKEKEI---------LDHLNRKITE 693

  Fly   628 LE----AQRNATRVMEENQQAKLKQSIEIKQDQLKKL----RAMLKQKPNNACLKEELQLVCESL 684
            ||    .::...:|..:.::.||::..|:..:|..:|    .||.:|      |:::|:...:.|
  Rat   694 LEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPEAMREQ------LQQQLKRDADLL 752

  Fly   685 ESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTG 749
            :.:.|.|||||||..|.||......|...:|     |..|:|..:..|...:|:
  Rat   753 DVESKHFEDLEFQQLEHESRLDEEKENLTQQ-----LLREVAEYQRNIVARKEK----------- 801

  Fly   750 SNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQLFEDLAGG 814
               ::.:..|    ::.::...:|.|:..:.:..|..|....:.|...:..|:     :..|.||
  Rat   802 ---ISALKKQ----ASHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKK-----YSSLTGG 854

  Fly   815 SCEQISFNLSLQGDRFEVNP--LERRVPSQDDIDRSC---------------------KVANDAP 856
            .             .|.:||  |:....|.::|:.||                     :.|:..|
  Rat   855 K-------------GFPINPNTLKEGYISVNEINESCGNSMNLSPSTQFPADADAAVTEPASAVP 906

  Fly   857 ISASQGAS------------TKIFDSIMEIERNRKLLLAQQGHQVIEHERQKMYD----LKKKSH 905
            :|..|.:.            :.:..|:.|...     .|.........:...:.|    |..|.|
  Rat   907 VSQPQSSEHQSAVCSGFMPPSTLSPSVTESSS-----AAWPEVMATPVDSFPLNDTPPPLPAKKH 966

  Fly   906 DEARTQYLLSTQQSMEQQRQLESDANGGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENNV 970
                     ..||..|||.              |...|.:|...|.|..:.|.:.:
  Rat   967 ---------RRQQPQEQQH--------------FRSLEERKKQHKEGLYLSDTLPR--------- 999

  Fly   971 QNRKSTGSSPTTTTTTTTGGGTTPQQ-----QRHSQPELEHHAIALG---------IGGGGSGGA 1021
              :|:|.|.....::.|.|..|||:.     |.:|...:..|::|..         :.|..:..|
  Rat  1000 --KKTTPSLSPHFSSATMGRSTTPKAHLPLGQSNSCGSVLPHSLATMTKDAESRRILRGRMNSSA 1062

  Fly  1022 GGANQMVARSPRPLSEANNCDATIEAPKFANGM---DSSASPAVADN-KRASSNSQDTASAGSGS 1082
            |..:|.::...|...|..:..|: |:..:.|..   |.|......|. ...||:|.:|:.:....
  Rat  1063 GYNHQQMSEGQRQKPEFYSRTAS-ESNVYLNSFHYSDRSYKDQAYDTLSLDSSDSMETSISACSP 1126

  Fly  1083 GNSGSGGST------------------------------------------------------AS 1093
            .|..|..::                                                      .|
  Rat  1127 DNISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETS 1191

  Fly  1094 DRKRVLPK----------HQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLH 1148
            .|::::.|          ..||||||||:...|.:||.|:|||||.||.|.||.:...:|||||.
  Rat  1192 QRQKLIEKEVKIREKQRAQARPLTRYLPVRKEDFDLRSHVETAGHNIDTCFHVSITEKTCRGYLI 1256

  Fly  1149 KLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHL-NASKSGRPHCTFI 1212
            |:|.....|.:||||.||.:....||:||.|.|.:|..||..|:|||.||| ||:||..|..||.
  Rat  1257 KMGGKIKTWKKRWFVFDRNKRTFSYYADKHEAKLKGVIYFQAIEEVYYDHLKNANKSPNPLLTFS 1321

  Fly  1213 VKTKKRSYNLQAASDSAARIWIDAIITGAQG 1243
            |||..|.|.:.|.|..|.|||:|.|:|||:|
  Rat  1322 VKTHDRIYYMVAPSPEAMRIWMDVIVTGAEG 1352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA	41..104	CDD:278899	14/76 (18%)
		PH-like	1142..1242	CDD:302622	52/100 (52%)
		PH	1143..1237	CDD:278594	49/94 (52%)
Phldb2	XP_038944805.1	Smc	<618..851	CDD:224117	58/301 (19%)
		DUF5401	<1139..>1206	CDD:375164	3/66 (5%)
		PH_PHLDB1_2	1247..1351	CDD:270192	52/103 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	102	1.000	Domainoid score	I6674
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	204	1.000	Inparanoid score	I3666
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45023at33208
OrthoFinder	1	1.000	-	-		FOG0003925
OrthoInspector	1	1.000	-	-		otm45110
orthoMCL	1	0.900	-	-		OOG6_105283
Panther	1	1.100	-	-	O	PTHR12156
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060