Protein Alignment CG5004 and Klp68D

DIOPT Version :10

• Sequence 1: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Sequence 2: NP_524029.2
• Gene: Klp68D / 39332
• FlyBaseID: FBgn0004381
• Length: 784
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 144/749 - (19%)
• Similarity: 259/749 - (34%)
• Gaps: 269/749 - (35%)

  Fly   238 IYKEQHQQQHQQAPQDLLTKVNNDRYDRYPKAGGLQIYSMNGVN----SDINNGPATGNNSGTGG 298
            ||.|:        .:||| |.|:...:...:..|:.:.:::.:|    .|:......||.:.|.|
  Fly   157 IYMEE--------LRDLL-KPNSKHLEVRERGSGVYVPNLHAINCKSVEDMIKVMQVGNKNRTVG 212

  Fly   299 GAELED---------MLKICTEYADRNNSMPSTHNVSSTSSITSSPIVQNRIKTNGSLPRDKNKS 354
            ...:.:         |:||  |..|...   :|..|...:.|..:. .:.:.||..|..|.|..|
  Fly   213 FTNMNEHSSRSHAIFMIKI--EMCDTET---NTIKVGKLNLIDLAG-SERQSKTGASAERLKEAS 271

  Fly   355 PFPQQAGVASSAN-ISLLSSSSGYENVRLLGPNRVEINGQIHVPASAGD---------GGSSSGV 409
            ..  ...::|..| ||.|:.||.                  |||.....         ||:|..:
  Fly   272 KI--NLALSSLGNVISALAESSP------------------HVPYRDSKLTRLLQDSLGGNSKTI 316

  Fly   410 SSNALAPTAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPL 474
            ....:.|:        |.|.|.:.||    :..:.|.|
  Fly   317 MIANIGPS--------NYNYNETLTT----LRYASRAK--------------------------- 342

  Fly   475 ASSAVVSTSKPIPIPSMVKPPLAPKPPAPNQQRDYEQLFKSFER-----KQQQLDRMVPAKRS-- 532
                           |:...|:..:.|...:.::|::..:..:|     :||:.::.|.||:.
  Fly   343 ---------------SIQNQPIKNEDPQDAKLKEYQEEIERLKRLIGPQQQQRSEKQVTAKKQRV 392

  Fly   533 --------NKNINNLTLNLQSVESQTQSPK-PSRKPAPAPRSIHLEQRQRRELIQRRK----QLK 584
                    .|.::: :|.:.::|...:... |....:.:.:....|..:..|.::|.:    :|.
  Fly   393 KKPKKETVTKEMSD-SLQVSTIEQPVEDDSDPEGAESESDKENEAEVAKSNEELERERVENSKLA 456

  Fly   585 RELAELPPSAGIEGLELKLGEQPLAPSASPRLQLQALQNRVCRLEAQRNATRVME-ENQQAKLKQ 648
            .:||||      || :|..|.:.|..:.|.|           ::|.::....:.| :.::.:::|
  Fly   457 AKLAEL------EG-QLVRGGKNLLDTYSER-----------QIELEKKLVEIAERKKREIEIQQ 503

  Fly   649 SIEIKQDQLKKLRAMLKQKPNNACLKEELQLVCESLESDRKTFEDLEFQYFEEESEHH------- 706
            .:|::::...::|      ..|..|::|::|....|......:..|:.:..:.:|:|:
  Fly   504 QLELQEETTLEIR------ERNVSLEQEVELKKRKLSKCYAKYLALQQELNDCKSDHNQDLRELE 562

  Fly   707 -ASHE---EFKRQ------------EQRLMLEAELAALRIQIGPDEEEP-------GSPTSPGST 748
             |.:|   |.|||            :|||..:|:.         |||:.       ..||.||..
  Fly   563 MAQNELVKELKRQLLIIDNFVPIEVKQRLYTQAKY---------DEEQEEWKFSSMSLPTPPGGD 618

  Fly   749 GSNLVNGVMSQSLFGSAELLC-PKRRN-------QE-------DLMSKSVNENMFYNHKIE--AN 796
            |.           |.|...:. |:||.       ||       .|..||.|   ..|:::|  ..
  Fly   619 GK-----------FSSKRPVSHPQRRRPTSEYALQEAKSNSPSSLRFKSEN---IVNYELEMPCR 669

  Fly   797 TSTPKRLPLQLFEDLAGGSCEQISFNLSLQ----------GDRFEV-----NPLERRVPSQDDID 846
            |:...|.|               ..:.|||          ||..::     |.|..|:.:
  Fly   670 TTQEYRTP---------------KVSASLQAVLAQAMQTGGDDIDIVDSHTNSLRSRLEN----- 714

  Fly   847 RSCKVAN-DAPISASQGASTKIFDSIMEIERNRK 879
                :.| :|...|..||...:..||..: ||.|
  Fly   715 ----IINANANGGAGPGAGVAVGSSIPNV-RNIK 743

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	37/187 (20%)
		Caldesmon	<664..801	CDD:460421	40/183 (22%)
		PH-like	1142..1242	CDD:473070
Klp68D	NP_524029.2	KISc	20..351	CDD:214526	52/282 (18%)
		Smc	<431..>580	CDD:440809	34/172 (20%)