Protein Alignment CG5004 and Klp64D

DIOPT Version :10

• Sequence 1: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Sequence 2: NP_523934.1
• Gene: Klp64D / 38611
• FlyBaseID: FBgn0004380
• Length: 677
• Species: Drosophila melanogaster
• Alignment Length: 819
• Identity: 152/819 - (18%)
• Similarity: 267/819 - (32%)
• Gaps: 291/819 - (35%)

  Fly   319 MPSTHNVSSTSSITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGVASSANISLLSSSSGYENVRLL 383
            ||.....:.|::.....|...|:... :.|.|||:    ..||..|:.::..::.:     :.::
  Fly     1 MPQEEANAGTTAQLDDEIENVRVVVR-TRPMDKNE----LSAGALSAISVDKINRA-----ITVM 55

  Fly   384 GPNRVEINGQIHVPASAG------------DGGSSSGVSSNALAPTAAVRASHENLNQNHSAT-- 434
            .||           |:|.            ||||:   ..:....||  |...:.:.:.::.|
  Fly    56 KPN-----------ATANEPPKTYYFDNVFDGGSN---QMDLYVDTA--RPIVDKVLEGYNGTIL 104

  Fly   435 ------TGGKYV----PQSPRTK-IRTNCMSPKKDVSFGN--------AFALAISPPPLASSAVV 480
                  ||..|.    |.||:|| |..|..:.    .||:        .|.:.:|...:.:..|
  Fly   105 AYGQTGTGKTYTMSGNPDSPQTKGIIPNAFAH----IFGHIAKAKENQKFLVRVSYMEIYNEEV- 164

  Fly   481 STSKPIPIPSMVKPPLAPKPPAPNQQRDY--EQLFKSFERKQQ-------------------QLD 524
                                      ||.  :.:.||.|.|::                   .|:
  Fly   165 --------------------------RDLLGKDVGKSLEVKERPDIGVFVKDLSGYVVHNADDLE 203

  Fly   525 RMVPAKRSNKNINNLTLNLQSVESQTQSPKPSRKPAPAPRSIHLEQRQRREL----IQRRKQLKR 585
            .::.....|:.:....:|.:|..|.            |..||.:|   |.||    :|..:..|.
  Fly   204 NIMRLGNKNRAVGATKMNQESSRSH------------AIFSITVE---RSELGEGDVQHVRMGKL 253

  Fly   586 ELAELPPSAGIE--------GLELK-----------LGE-------------------------- 605
            :|.:|   ||.|        |..||           ||.
  Fly   254 QLVDL---AGSERQSKTQASGQRLKEATKINLSLSVLGNVISALVDGKSTHIPYRNSKLTRLLQD 315

  Fly   606 -----------QPLAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKK 659
                       ..::|:.|..::..:......|.:..:|...:.||.:.|.|:..    |:::.:
  Fly   316 SLGGNSKTVMCATISPADSNYMETISTLRYASRAKNIQNRMHINEEPKDALLRHF----QEEIAR 376

  Fly   660 LRAMLKQKPNNACLKEELQLVCESLESDRKTFED-----LEFQYFEEESEHHASHEEFKRQEQRL 719
            ||   ||......|:||    ..|.|.:..|.:|     ||.:.  |.|...|..::.|::.::.
  Fly   377 LR---KQLEEGDSLEEE----PPSSEEEEDTADDELEAPLEIEL--ESSTIQAVEKKPKKKREKT 432

  Fly   720 MLEAELAALR-------IQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPKRRNQED 777
            ..|.|..|.|       |:....|:|         |..|.:..:..:.|.|...|| .|.:.||.
  Fly   433 DAEKEELAKRKNEHQKEIEHAKTEQE---------TLRNKLVSLEGKILVGGENLL-EKAQTQEL 487

  Fly   778 LMSKSVNENMFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNLSLQGDRFEVNPLERRVPSQ 842
            |:.:|:.|...:....||...|                                   |:::...:
  Fly   488 LLEQSIAELEQHEKSEEALKQT-----------------------------------LQQKATER 517

  Fly   843 DDIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKLLLAQQGHQVIEHERQK--MYD-LKKKS 904
            .||:.......|    ||.|.:.|| ..:|::....|..||.|..   ||:|:|  :|: ::..|
  Fly   518 IDIEERYSTLQD----ASTGITKKI-HRVMQMLMGVKSELADQQQ---EHQREKEGIYENIRSLS 574

  Fly   905 HDEARTQYLLSTQQSMEQQRQLESDANGGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENN 969
            .:.|..:.:|::....|.|..:....:..:|.               ||.....|.....:...:
  Fly   575 RELALCELVLNSYVPKEYQSMINQYTHWNEDI---------------GEWQLKCVAYTGNNMRKH 624

  Fly   970 VQNRKSTGSSPT------TTTTTTTGGGTTPQQQRHSQP 1002
            :...|::|..|.      ...:..|.|.:.|.:.:.::|
  Fly   625 ISAHKTSGKEPDFLDLSHVYLSYNTDGVSNPMRSKSARP 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	45/231 (19%)
		Caldesmon	<664..801	CDD:460421	37/148 (25%)
		PH-like	1142..1242	CDD:473070
Klp64D	NP_523934.1	KISc_KIF3	19..352	CDD:276822	68/407 (17%)
		Smc	<433..>578	CDD:440809	42/197 (21%)