DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5004 and Klp59C

DIOPT Version :9

Sequence 1:	NP_573195.1	Gene:	CG5004 / 32698	FlyBaseID:	FBgn0260748	Length:	1247	Species:	Drosophila melanogaster
Sequence 2:	NP_611759.1	Gene:	Klp59C / 37671	FlyBaseID:	FBgn0034824	Length:	626	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	102/577 - (17%)
Similarity:	192/577 - (33%)	Gaps:	202/577 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   544 QSVESQTQSP-----KPSRKPAPAPRS---IHLEQRQRRELIQRRK-----QLKRELAELPPSAG 595
            |.:.:.:.||     .|.::.||..|.   :|..:|.|:|..:||:     :|.||..:
  Fly    89 QRIATGSLSPVLATAPPRQQTAPPVREDEVVHQAERMRKERERRREAQARTRLDREQGK------ 147

  Fly   596 IEGLELKLGEQPLAPS--ASPRLQLQALQNRVCRLEAQR----------NATRVM--EENQQAKL 646
                    .|.|..|:  .:..::||..|     :|:||          |..::|  ...:..:.
  Fly   148 --------NEDPGNPNWEVARMIRLQREQ-----MESQRVRSGTTNERINCHQIMVCVRKRPLRR 199

  Fly   647 KQSIEIKQD--QLKKLRAMLKQKPNNACLKEELQLVCESLESDRKTFEDLEFQY---FEEESEHH 706
            |:..:.:||  .:.....::..:|     ::.:.||        |..|:..|::   |:||..:.
  Fly   200 KELADREQDVVSIPSKHTLVVHEP-----RKHVNLV--------KFLENHSFRFDYVFDEECSNA 251

  Fly   707 ASHEEFKRQEQRLMLEAELAALRI--QIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLC 769
            ..:|...|...:.:.:..:|....  |.|..:........||...|:: :|:.:.:
  Fly   252 TVYEFTARPLIKHIFDGGMATCFAYGQTGSGKTYTMGGQFPGRHQSSM-DGIYAMA--------- 306

  Fly   770 PKRRNQEDLMS--KSVNENMFYNHKIEA-----------NTSTPKRLPLQLFEDLAGGSCEQISF 821
                 .:|:.|  |:|..|.. |.|:..           :...|.:..|::.||.
  Fly   307 -----AKDVFSTLKTVPYNKL-NLKVYCSFFEIYGTRVFDLLMPGKPQLRVLEDR---------- 355

  Fly   822 NLSLQGDRFEVNPLERRVPSQD--DIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKLLLAQ 884
            |..:|......||::......|  ::..|.:.:.....::....|..:|..::......||
  Fly   356 NQQVQVVGLTQNPVQNTAEVLDLLELGNSVRTSGHTSANSKSSRSHAVFQIVLRSAAGEKL---- 416

  Fly   885 QGHQVIEHERQKMYDL--KKKSHDEARTQYLLSTQQSMEQQRQLE-SDAN--------------- 931
                   |.:..:.||  .::..|.:          |.::|.:|| |:.|
  Fly   417 -------HGKFSLIDLAGNERGADNS----------SADRQTRLEGSEINKSLLVLKECIRALGR 464

  Fly   932 ---------------------GGKDAKL------------FEKTELQKLNQKPGEPVDDQVQKIA 963
                                 |||..|.            .|.| |..|...      |:|::::
  Fly   465 QSSHLPFRGSKLTQVLRDSFIGGKKVKTCMIAMISPCLHSVEHT-LNTLRYA------DRVKELS 522

  Fly   964 GD----KENNVQNRKSTGSS------------PTTTTTTTTGGGTTPQQQRHSQPEL 1004
            .:    |.....|..||..|            |..::|:..|||...||..::..:|
  Fly   523 VESIPSKRMPDANLGSTSMSDIVCQSSTQRLFPCASSTSMPGGGNQAQQHTNTANDL 579

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA	41..104	CDD:278899
		PH-like	1142..1242	CDD:302622
		PH	1143..1237	CDD:278594
Klp59C	NP_611759.1	KISc_KIF2_like	187..519	CDD:276818	62/398 (16%)
Klp59C	NP_611759.1	Kinesin	193..520	CDD:278646	62/393 (16%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437809
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930