DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5004 and neb

DIOPT Version :9

Sequence 1:	NP_573195.1	Gene:	CG5004 / 32698	FlyBaseID:	FBgn0260748	Length:	1247	Species:	Drosophila melanogaster
Sequence 2:	NP_476817.1	Gene:	neb / 35293	FlyBaseID:	FBgn0004374	Length:	1121	Species:	Drosophila melanogaster

Alignment Length:	417	Identity:	83/417 - (19%)
Similarity:	142/417 - (34%)	Gaps:	134/417 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LVSLGGGRLSTAVTIHYIHIGDTTIGSAASCSISLNGSGVRPLHCTIYRSDANEVTLVP-EKDSR 82
            ||.:|.|||...             .|::...|.|:|..|...||:|......::.::| .:|..
  Fly   657 LVRIGRGRLPGG-------------SSSSQPDIVLDGPLVALQHCSIEHERGGKLYVIPGSEDFE 708

  Fly    83 LLIDGAPILEETKLSQGAMITIGNSNYLRFNNP-----------------------DEAQMMRSA 124
            ..::|..:.:..:|..|..:.||.|:|.|.:||                       .:.|.:||.
  Fly   709 TYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQEILQKQEQQLRSE 773

  Fly   125 MGSNERISMPQI--DFTQSARQAHELSQSLELESFYESIINPINNPSTYELECPKVFSSDLVTVN 187
            :.:.:|.::.:|  :..|.||...|..|.||||.|              :.:|    :|:::...
  Fly   774 LEAEKRAALTKIEQERAQHARDFEERLQCLELEQF--------------KYKC----NSEMLETE 820

  Fly   188 MPAKDVLGQKYASFARNLAENH---RNEKQLNNQYAKG--------VGSNGGYWNVPSNAAIYKE 241
            ..|..:..|          :.|   |:|..::....|.        :..|....::.....:.||
  Fly   821 RQALALAQQ----------QEHTPLRHEDAVSTPAQKSTILEDIQRIMLNPSEESLHKTQLMVKE 875

  Fly   242 QHQQQHQ----------QAPQD---------LLTKVNNDRYDRYPKAGGLQIYSMNGVNSDINNG 287
            ..|:..|          |.|.:         :|.|....:.: :|.|       ..||..|:
  Fly   876 ATQRCRQLDLPLEFRQTQTPDEFGLLRTVILILDKQRGLKAE-WPTA-------RLGVWLDL--- 929

  Fly   288 PATGNNSGTGGGAELEDMLKICTEY-----------ADRNNSMPSTHNVSSTSSITSSPIVQNRI 341
                    ....||.::.|...|.:           ||.|.::..|||   :|.|..:......:
  Fly   930 --------VRDNAEQQEKLNATTIFQSVEVDWEPLDADLNETLSDTHN---SSRIALNLSAMKDV 983

  Fly   342 KTNGSLPR----DKNKSPFPQQAGVAS 364
            ..|..|.|    ..:||..|:|....|
  Fly   984 LLNKPLKRLLNASSSKSNTPRQTSTPS 1010

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA	41..104	CDD:278899	13/63 (21%)
		PH-like	1142..1242	CDD:302622
		PH	1143..1237	CDD:278594
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816
		KISc	120..525	CDD:214526
		Kinesin_assoc	524..657	CDD:292801	83/417 (20%)
		FHA	634..740	CDD:238017	24/95 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437953
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930