DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5004 and nod

DIOPT Version :9

Sequence 1:	NP_573195.1	Gene:	CG5004 / 32698	FlyBaseID:	FBgn0260748	Length:	1247	Species:	Drosophila melanogaster
Sequence 2:	NP_001285129.1	Gene:	nod / 32107	FlyBaseID:	FBgn0002948	Length:	666	Species:	Drosophila melanogaster

Alignment Length:	471	Identity:	92/471 - (19%)
Similarity:	158/471 - (33%)	Gaps:	145/471 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   520 QQQLDRMVPAKRSNKNINNLTLNLQSVESQTQSPKPSRKPAPAPRSIHLEQRQRRELIQRRKQLK 584
            |..|..::.....|:.:....:|..|..|.            |..:||::.:....        :
  Fly   177 QADLHHILELGTRNRRVRPTNMNSNSSRSH------------AIVTIHVKSKTHHS--------R 221

  Fly   585 RELAELPPSAGIEGLELKLGEQPLAPSASPRLQLQALQ-NRVCRLEAQRNA---------TRVME 639
            ..:.:|   ||.||:. :.|.:.:|......:.|..|. |:|....|..:.         |.|::
  Fly   222 MNIVDL---AGSEGVR-RTGHEGVARQEGVNINLGLLSINKVVMSMAAGHTVIPYRDSVLTTVLQ 282

  Fly   640 EN---------------QQAKLKQSIEIKQ--DQLKKLR----AMLKQKPNNACLKEEL--QLVC 681
            .:               .|..|.:::...:  ...||||    .:.:||.:.|.....:  |.:|
  Fly   283 ASLTAQSYLTFLACISPHQCDLSETLSTLRFGTSAKKLRLNPMQVARQKQSLAARTTHVFRQALC 347

  Fly   682 ESL---------------ESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLE---AELAAL 728
            .|.               :|...|.:.|........||...:.:..||..:.|.||   .||:::
  Fly   348 TSTAIKSNAANHNSIVVPKSKYSTTKPLSAVLHRTRSELGMTPKAKKRARELLELEETTLELSSI 412

  Fly   729 RIQ------IG--------------PDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPKRR 773
            .||      :|              |..:||...:|..||            |.|..|...||.
  Fly   413 HIQDSSLSLLGFHSDSDKDRHLMPPPTGQEPRQASSQNST------------LMGIVEETEPKE- 464

  Fly   774 NQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQLFEDLAGGSCEQISFNL-SLQGDRFEVNPLER 837
                  |..|.::|       ...:.|..:..|||..    :...||... |.|.:...:.|:|.
  Fly   465 ------SSKVQQSM-------VAPTVPTTVRCQLFNT----TISPISLRASSSQRELSGIQPMEE 512

  Fly   838 RV---PSQDDIDRSCKVANDAPISASQGASTKIFDSIMEIERNRKL---------LLAQQGHQVI 890
            .|   |.|..:.||.::|:... |.:.||..|    :|.:.|:.:|         ::.:.....|
  Fly   513 TVVASPQQPCLRRSVRLASSMR-SQNYGAIPK----VMNLRRSTRLAGIREHATSVVVKNETDAI 572

  Fly   891 EHERQKMYDLKKKSHD 906
            .|.|..:.  ||::.:
  Fly   573 PHLRSTVQ--KKRTRN 586

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA	41..104	CDD:278899
		PH-like	1142..1242	CDD:302622
		PH	1143..1237	CDD:278594
nod	NP_001285129.1	KISc	8..325	CDD:214526	29/171 (17%)
		KISc	8..318	CDD:276812	25/164 (15%)
		ComEA	540..648	CDD:224472	10/53 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437901
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930