Protein Alignment CG5004 and phldb3

DIOPT Version :10

• Sequence 1: NP_573195.1
• Gene: CG5004 / 32698
• FlyBaseID: FBgn0260748
• Length: 1247
• Species: Drosophila melanogaster
• Sequence 2: XP_002939188.2
• Gene: phldb3 / 100491291
• XenbaseID: XB-GENE-6045638
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 837
• Identity: 186/837 - (22%)
• Similarity: 318/837 - (37%)
• Gaps: 293/837 - (35%)

  Fly   486 IPIP----SMVKPPLAP----------KPPAPNQQRDY-----EQLFKSFERKQQQLDRMVPAKR 531
            :|:|    :....|::|          :|||...:||.     .::..|.:.::......|||::
 Frog    15 LPVPREPANQKTKPMSPERKSEEECRCEPPAEEVERDSVSSEGGRVTDSTDEEESSSTESVPAQQ 79

  Fly   532 SNKNINNLTLNLQSVESQTQSPKPSRKPAPAPRSIHLEQRQRRELIQRRK---QLKRELAELPPS 593
            .           ::|.::.|....:::.........|||..|...:|||:   :::.|:|.|...
 Frog    80 E-----------KAVGNEVQRCLEAKQLKVMAHISKLEQSLRELQLQRRELNIEVEMEVALLEGE 133

  Fly   594 AGIEGLELKLGEQPLAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAK-LKQSIEIKQDQL 657
            ...|..|:: .|:.|..|...:|:   ...|..:.|..::..::.:|.::.| |:|.|...:.||
 Frog   134 LRTEKKEME-KEENLIRSLHEKLR---ETERKWQEEKDKDKLKLRDEKKKIKDLEQKISEGKSQL 194

  Fly   658 KKLRAMLKQKPNNACLKEELQLVCESLESDRKTFEDLEFQYFEEES----EHHASHEEF------ 712
            :|....|:::     |::.:|.:.|::|:..|:|||||||..|.||    |..:|:.:.
 Frog   195 EKQPESLREQ-----LRKNIQEMTETMEAAVKSFEDLEFQQLESESSRDEERESSYRQISQDISK 254

  Fly   713 ------KRQEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPK 771
                  :|:::.|.||..:.....|...:.:.....           |..:.|||        .|
 Frog   255 RQNELNRRKDKVLRLEEHIQGAEDQAQVERQRLSEE-----------NTRVFQSL--------NK 300

  Fly   772 RRNQEDLMSKSVNENMFYNHKIEANT--------STPKR-----------LPLQLFEDLAGGSCE 817
            .::|.:.::....::...|.|.:::|        |.|||           .||.|.    |.:|.
 Frog   301 EKDQLESLNALSGKDQGQNEKPQSSTRKALQRTNSLPKRRASAPFVRPTDRPLSLH----GNTCL 361

  Fly   818 Q---ISFNLSLQGDR------FEVNP----LERRVPSQDDIDRSC--KVAND-APISASQGASTK 866
            :   ::.:|::..:.      ..::|    .:.|:|..||...|.  |:.:| :.:..|.|...|
 Frog   362 ESAGLALHLAVSSNNTGGQIALAISPNLQITQARLPQVDDRKGSNREKIPSDISTLQLSYGPLPK 426

  Fly   867 IFDSIMEIERNRKLLLAQQGHQVIEHERQKMYDLKKKSHDEARTQYLLSTQQSMEQQRQLESDAN 931
                |.||||..:..||         |::::.    |:.:|.|.        :.|..|:|||
 Frog   427 ----IAEIERQLREALA---------EKERLL----KAREEKRA--------AKEMTRRLES--- 463

  Fly   932 GGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENNVQNRKSTGSSPTTTTTTTTGGGTTPQQ 996
                                                                             
 Frog   464 ----------------------------------------------------------------- 463

  Fly   997 QRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANGMDSSASPA 1061
               ||                       ||:....|.|:                     :|.||
 Frog   464 ---SQ-----------------------NQVKTEEPAPV---------------------TAKPA 481

  Fly  1062 VADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLPKHQRPLTRYLPIFSPDLNLRHHIETA 1126
            :.:.|                          .:.::||...:.|        :| |:||.|:|.:
 Frog   482 LPETK--------------------------GEPEKVLSVLRAP--------AP-LDLRSHLEAS 511

  Fly  1127 GHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATI 1191
            ||.::.||||.|....|:|||.|:|.....|.:||||.|||:..|.||:||.|.|.:|..||..|
 Frog   512 GHCVETCPHVRVSPTCCKGYLVKMGGRIKTWRKRWFVFDRQKRRLAYYTDKDEVKLKGVIYFQAI 576

  Fly  1192 DEVYLDHL-NASKSGRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY 1247
            :|||.||| :|.||..|..||.:||.:|.:.:.|.:..|.|||:|.::|.|:.|..|
 Frog   577 EEVYYDHLRSAFKSPHPKLTFCLKTFERLFCMVAPTPEAMRIWMDVMVTAAEENSRY 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5004	NP_573195.1	FHA_PHLB1	1..122	CDD:438765
		SMC_N	<570..730	CDD:481474	46/179 (26%)
		Caldesmon	<664..801	CDD:460421	33/160 (21%)
		PH-like	1142..1242	CDD:473070	47/100 (47%)
phldb3	XP_002939188.2	Smc	<77..>332	CDD:440809	61/293 (21%)
		PH-like	528..628	CDD:473070	47/99 (47%)