DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Arpc3B and ARPC3

DIOPT Version :9

Sequence 1:	NP_573193.1	Gene:	Arpc3B / 32696	FlyBaseID:	FBgn0065032	Length:	174	Species:	Drosophila melanogaster
Sequence 2:	NP_001265485.1	Gene:	ARPC3 / 10094	HGNCID:	706	Length:	178	Species:	Homo sapiens

Alignment Length:	177	Identity:	107/177 - (60%)
Similarity:	137/177 - (77%)	Gaps:	4/177 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPAFHSEIEDFQAS-VGNMALLPLRTQVRGPAPTVDIPNDIIDESLYFWKSNIFFRTYEVKSEVD 64
            |||:||.:.|.... :|||||||:|:|.:||||......||:||::|::|:|:||:.||:|:|.|
Human     1 MPAYHSSLMDPDTKLIGNMALLPIRSQFKGPAPRETKDTDIVDEAIYYFKANVFFKNYEIKNEAD 65

  Fly    65 RVLIYITLYITECLKRLARCTSKSQGQQELYTLAISRFDIPGDAGFPLNGIYTKP---EDPELMR 126
            |.||||||||:||||:|.:|.|||||::|:|||.|:.|.|||:.|||||.||.||   ::.|:||
Human    66 RTLIYITLYISECLKKLQKCNSKSQGEKEMYTLGITNFPIPGEPGFPLNAIYAKPANKQEDEVMR 130

  Fly   127 QYFLQLRQETGNRLLEKVFDTPDGKPSKWWICFAKKKFMEKSLSGPG 173
            .|..|||||||.||.|||||..:.||||||.||.|::||.|||||||
Human   131 AYLQQLRQETGLRLCEKVFDPQNDKPSKWWTCFVKRQFMNKSLSGPG 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Arpc3B	NP_573193.1	P21-Arc	1..169	CDD:281983	101/171 (59%)
ARPC3	NP_001265485.1	P21-Arc	1..173	CDD:397948	101/171 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165160522
Domainoid	1	1.000	229	1.000	Domainoid score	I2475
eggNOG	1	0.900	-	-		E1_KOG3155
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3372
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54322
OrthoDB	1	1.010	-	-		D1451115at2759
OrthoFinder	1	1.000	-	-		FOG0004013
OrthoInspector	1	1.000	-	-		otm40583
orthoMCL	1	0.900	-	-		OOG6_102731
Panther	1	1.100	-	-	O	PTHR12391
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2769
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.770