DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and AVT7

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_012178.1	Gene:	AVT7 / 854721	SGDID:	S000001350	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	467	Identity:	95/467 - (20%)
Similarity:	171/467 - (36%)	Gaps:	131/467 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 TSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAV-------MCVHCERMLI--RGS 139
            :|.|.:..:|.|..||||..|:...||:.|:....||..:.||       :...|.:.||  |.|
Yeast     5 SSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNS 69

  Fly   140 VLAVERTPGVDFLDYPETVEKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLH 204
            ....     :..|.|| |:...|:            :.:||:   |   ||....|.|.|.:...
Yeast    70 SFFT-----LCMLTYP-TLAPIFD------------LAMIVQ---C---FGVGLSYLVLIGDLFP 110

  Fly   205 QVL--QQNGIVISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPM 267
            .:.  ::|..:|:.:::    ::|..:...:..|||.|.:.|||...:...:.:........|.:
Yeast   111 GLFGGERNYWIIASAVI----IIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGEL 171

  Fly   268 PSV-------GDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFF 325
            .::       ...|.|.|   |...|...:|::.|...:.|:.|.::.....:..| |:|:::..
Yeast   172 TNILRNDICWWKIHDFKG---LLSTFSIIIFAFTGSMNLFPMINELKDNSMENITF-VINNSISL 232

  Fly   326 TTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFF-----VMIKI 385
            :||||:..|...|:.:|.|..|::.||.....::..:.|......:.|.:|:.|.     |...|
Yeast   233 STALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVI 297

  Fly   386 LW-------------PPLKRSNNCTQKYPIT-------------------SQVCL---------- 408
            :|             |.:......:...||:                   .|.||
Yeast   298 IWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGS 362

  Fly   409 -----------------------------RFF-----MVMMTFGVALVVPKLNLFISLIGALCST 439
                                         ||:     :::..:.:||.|....|.:|.:||..||
Yeast   363 IESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGST 427

  Fly   440 CLAFVIPVLIDF 451
            .::|.:|.|:.:
Yeast   428 SISFTLPGLLGY 439

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	95/467 (20%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	95/467 (20%)
AVT7	NP_012178.1	Aa_trans	4..477	CDD:279788	95/467 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	3	2.920