DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and AT4G38250

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_195538.1	Gene:	AT4G38250 / 829982	AraportID:	AT4G38250	Length:	436	Species:	Arabidopsis thaliana

Alignment Length:	469	Identity:	123/469 - (26%)
Similarity:	214/469 - (45%)	Gaps:	62/469 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 GRQNDKSLEKNPERFTKNVTEKGADPENGD-PVRRRGHE-TSELEAATHLFKGSVGAGLFAMGDC 108
            |.||:.|        :.:.|.|...|...| |:..:|.. :|:.:...::|...||||:..:...
plant     2 GFQNEAS--------SSSYTLKIPPPAREDSPLLGKGPPLSSQFKTFANVFIAVVGAGVLGLPYA 58

  Fly   109 FKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLD-YPETVEKCFEHGPRPLRKM 172
            ||..|.....:||..::|:..||..:|:     ...|.     || :...:.|....|.......
plant    59 FKRTGWLMGVLLLVSVSVLTHHCMMLLV-----YTRRK-----LDSFNAGISKIGSFGDLGFAVC 113

  Fly   173 SRVMKLIVEMFLCVTQFGFCAIYFVFITENL-------------HQV--LQQNGIVISMSMVMLI 222
            ..:.:::|::|:.::|.|||..|.:||...|             ||.  |....:.:|...:.:.
plant   114 GSLGRIVVDLFIILSQAGFCVGYLIFIGTTLANLSDPESPTSLRHQFTRLGSEFLGVSSKSLYIW 178

  Fly   223 TLLPAM--IPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTGGAQLALF 285
            ...|..  :.|:.| |.:::|:|:||::..| |.:|.:.:..|...:....|...| ||..|.|:
plant   179 GCFPFQLGLNSIKT-LTHLAPLSIFADIVDL-GAMAVVIVEDSMIILKQRPDVVAF-GGMSLFLY 240

  Fly   286 -FGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSI 349
             .|.|::|:||:.::|||.:.|:..:||..   ||...|.|.:.::|..|.:.|:.:||:....|
plant   241 GMGVAVYSFEGVGMVLPLESEMKDKDKFGK---VLALGMGFISLIYIAFGILGYLAFGEDTMDII 302

  Fly   350 TLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCTQKYPITSQVCLRFFMVM 414
            |.||....| |.||::...:.:|..:|:....:.:|:.....|.         .....||:.:|:
plant   303 TANLGAGLV-STVVQLGLCINLFFTFPLMMNPVFEIVERRFSRG---------MYSAWLRWVLVL 357

  Fly   415 MTFGVALVVPKLNLFISLIGALCSTC--LAFVIPVLIDFVTRAQVPKALGVWSYIKNILILTVAV 477
            ....|||.||....|:||:|:  |||  |.||:|.|...:.   ..:.:|...:..:..|:.:.|
plant   358 AVTLVALFVPNFADFLSLVGS--STCCVLGFVLPALFHLLV---FKEEMGWLQWSSDTAIVVLGV 417

  Fly   478 LGIVTGTYQSIVEI 491
            :..|:||:.|:.||
plant   418 VLAVSGTWSSLSEI 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	111/428 (26%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	110/424 (26%)
AT4G38250	NP_195538.1	SLC5-6-like_sbd	34..429	CDD:382020	111/425 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.970