DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and slc32a1

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001074170.1	Gene:	slc32a1 / 798575	ZFINID:	ZDB-GENE-061201-1	Length:	530	Species:	Danio rerio

Alignment Length:	505	Identity:	113/505 - (22%)
Similarity:	204/505 - (40%)	Gaps:	81/505 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QSDQKAIEAAGEMGRTLEITGRQNDKSLEKN----PERFTKNVTEKGADPENGDPVRRRGHETSE 86
            ::|:...|..||||   |....:.|...:::    |...:|   :.|...|.|:|.:.|   .:.
Zfish    68 KNDEMGGEGGGEMG---EDGMAEGDSHYQRDGTGPPPSASK---DGGLCSEIGNPDKPR---ITA 123

  Fly    87 LEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPG--V 149
            .||..::.....|..:..:.....:||..|..::: ..||:|.:..::||  :.|..|...|  |
Zfish   124 WEAGWNVTNAIQGMFVLGLPYAILHGGYLGLFLII-FAAVVCCYTGKILI--ACLYEENEDGQLV 185

  Fly   150 DFLD-YPETVEKCFEHGPRPLRKMSRVMKL--IVEMFLCVTQFGFCAIYFVFITENLH------- 204
            ...| |.:....|.  .||.......|:.:  |:|:.:.      |.:| |.::.||.
Zfish   186 RVRDSYVDIANACC--APRFPALGGHVVNVAQIIELVMT------CILY-VVVSGNLMYNSFPTL 241

  Fly   205 QVLQQNGIVISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAF-----SD 264
            .|.|::..:|:.:     .|||.   :.:.|||.:|..||...:|..  :|..|.||:     .|
Zfish   242 PVSQRSWAIIATA-----ALLPC---AFLKNLKAVSKFSLLCTLAHF--VINILVIAYCLSRARD 296

  Fly   265 GPMPSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTAL 329
            .....|   ..:....:..:..|..:|||.....:..|..:|::|.:|..   ::|.|......|
Zfish   297 WAWDKV---KFYIDVKKFPISIGIIVFSYTSQIFLPSLEGNMQKPSEFHC---MMNWTHIAACIL 355

  Fly   330 FIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKIL-------- 386
            ......|:|:.|.:|....||.||  ......||.:.......|.||:.||..:::|
Zfish   356 KGLFALVAYLTWADETKEVITDNL--PSSIRAVVNLFLVSKALLSYPLPFFAAVEVLEKTFFQDG 418

  Fly   387 ----WPPLKRSNNCTQKYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPV 447
                :|.....:...:.:.::    ||..:|:.|..:|:.||...|.:.|.|:|....|.|::|.
Zfish   419 GRAFFPDCYGGDGRLKSWGLS----LRCALVVFTMLMAIYVPHFALLMGLTGSLTGAGLCFLLPS 479

  Fly   448 LIDFVTRAQVPKALGVWSYI-KNILILTVAVLGIVTGTYQSIVEIVKEFK 496
            |  |..:....|.|  |..: .::.|..:..:..::|...|:..:::.:|
Zfish   480 L--FHLKLLWRKLL--WHQVFFDVAIFVIGGICSISGFIHSVEGLIEAYK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	97/436 (22%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	96/433 (22%)
slc32a1	NP_001074170.1	Aa_trans	120..517	CDD:279788	97/437 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594474
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840