DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4991 and slc38a8

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	XP_012816686.1	Gene:	slc38a8 / 733502	XenbaseID:	XB-GENE-5766974	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	469	Identity:	97/469 - (20%)
Similarity:	181/469 - (38%)	Gaps:	91/469 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    72 ENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLI 136
            |.|.|      ..|.:.|...:.|.::||||......|...|.....|::.:::::      .||
Frog    26 EGGTP------SLSSMGAIFIMLKSALGAGLLNFPWAFNKVGGMHTAIMVELVSLI------FLI 78

  Fly   137 RGSVLAVERTPGVDFLDYPETVEK-----------CFEHGPRPLRKMSRVMKLIVEMFLCVTQFG 190
            .|.|:          |.|..::.|           |   || .:.|:..:..:|....:||.
Frog    79 SGLVI----------LGYASSLSKHSTYQGVVKDLC---GP-AIGKLCGICYIINLFMICVA--- 126

  Fly   191 FCAIYFVFITEN----LHQVLQQNGIVISMS---------------MVMLITLLPAMIPSLMTNL 236
                 |:.:.|:    |...:..|..:.:||               ::.|:.:||..||..::..
Frog   127 -----FLRVVEDQLEKLCDSIHSNNTLYAMSEVSQSWYMDPRFAITVLCLVIILPLSIPKEISFQ 186

  Fly   237 KYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTGGAQLALFFG---TALFSYEGIAL 298
            ||   .|:...:|..: |...:.|.:.....|.:......:..|..|..|.   |..|.::....
Frog   187 KY---TSILGTLAACY-LTVMIIIKYYVMEHPVLIKHEFSSNAASWASMFSVVPTICFGFQCHEA 247

  Fly   299 ILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVV 363
            .:.:.:||:. :..|....|...:|.....::.|||....:.:||.||..|.::....:|...:.
Frog   248 CVTIYSSMKN-KCLSNWAAVSVVSMLICLLIYSFTGIYGSLTFGEAVAADILMSYPGNDVAVIIA 311

  Fly   364 KVIAALGVFLGYPIQFFV---MIKILW-PPLKRSNNCTQKYPITSQVCLRFFMVMMTFGVALVVP 424
            :::..:.:...|||...:   :|:..| ...::|...|..|....:|.:....:::|..:||.||
Frog   312 RLLFTISIITIYPIILLLGRCVIQEAWLNHREKSLFVTLTYERCVRVVITVLWILVTLLIALFVP 376

  Fly   425 KLNLFISLIGALCSTCLAFVIPVLI--------DFVTRAQVPKALGVWSYIKNILILTVAVLGIV 481
            .::..||:||.: |....|:.|.|.        ...|:|:  ..|..|..|.  ::....|.|
Frog   377 DISEVISVIGGI-SAFFIFIFPGLCLVCAVESEPMNTKAK--SCLTAWGAIS--VVCGAFVFG-- 434

  Fly   482 TGTYQSIVEIVKEF 495
            ..|..:::||:.:|
Frog   435 QSTTIAVMEIIAKF 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	91/451 (20%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	91/448 (20%)
slc38a8	XP_012816686.1	SLC5-6-like_sbd	37..442	CDD:294310	90/444 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930