Protein Alignment CG4991 and SLC38A7

DIOPT Version :10

• Sequence 1: NP_001259638.1
• Gene: CG4991 / 32695
• FlyBaseID: FBgn0030817
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_060701.1
• Gene: SLC38A7 / 55238
• HGNCID: 25582
• Length: 462
• Species: Homo sapiens
• Alignment Length: 498
• Identity: 118/498 - (23%)
• Similarity: 195/498 - (39%)
• Gaps: 114/498 - (22%)

  Fly    35 AGEMGRTLEITGRQNDKSLEKNPERFTKNVTEKGADPENGDPVRRRGHETSELEAATHLFKGSVG 99
            |||..|.|:            :|...|...:|..|.|...|    || .||.|.|...:....:|
Human    19 AGERARLLQ------------SPCVDTAPKSEWEASPGGLD----RG-TTSTLGAIFIVVNACLG 66

  Fly   100 AGLFAMGDCFKNGGLAGATILLP------IIA--VMCVHCERMLIRGSVLAVERTPGVDFLDYPE 156
            |||......|...|...|.|.|.      ||:  |:..:|       |..:.|||       |.|
Human    67 AGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYC-------SQASNERT-------YQE 117

  Fly   157 TV-EKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIV------- 213
            .| ..|           .::..::.|:.:.|..||.|..:.:.|.:      ||:.|:
Human   118 VVWAVC-----------GKLTGVLCEVAIAVYTFGTCIAFLIIIGD------QQDKIIAVMAKEP 165

  Fly   214 ------------ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGP 266
                        .::|:...:.:||..||..:...||.|    |.:|...:.:.|.:.|.:. .|
Human   166 EGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYAS----FLSVVGTWYVTAIVIIKYI-WP 225

  Fly   267 MPSVGDRHLFTGGAQ-LALF--FGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTA 328
            ...:...::.|..|. :|:|  ..|..|.::.....:|:.|||::|| ..|..||:.:.|....|
Human   226 DKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPE-VKTWGGVVTAAMVIALA 289

  Fly   329 LFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFF---VMIKILWPPL 390
            :::.||...::.:|..|...:.|:...|::...|.:....|.|...|||..|   .:::.||  |
Human   290 VYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLW--L 352

  Fly   391 KRSNNCTQKYPITSQV----------CLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVI 445
            :     .|..|:...|          .|.:|  ::|..:||.:|.:...||:||.| :.|..||.
Human   353 R-----YQGVPVEEDVGRERRRRVLQTLVWF--LLTLLLALFIPDIGKVISVIGGL-AACFIFVF 409

  Fly   446 PVLIDF---VTRAQVPKALGVWSYIK-NILILTVA--VLGIVT 482
            |.|...   ::..:..|....|..:. .:|::|:.  :.|..|
Human   410 PGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTT 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:444915	105/451 (23%)
SLC38A7	NP_060701.1	SLC5-6-like_sbd	49..457	CDD:444915	106/452 (23%)