DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and slc38a5

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001011051.1	Gene:	slc38a5 / 496461	XenbaseID:	XB-GENE-5856213	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	532	Identity:	104/532 - (19%)
Similarity:	206/532 - (38%)	Gaps:	112/532 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DLTVLHRYFSGRLFPARTQQQQSDQKAIEAAGEMGRTLEITGRQNDKSLEKNPERFTKNVTEKGA 69
            |..:|:...|..|...|...:..|: |.|||                 ||:. |:|..:|.
Frog    11 DAHMLNGSVSESLNTERLNMEDGDE-AEEAA-----------------LEER-EKFLSHVV---- 52

  Fly    70 DPENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERM 134
             |:..:.....| :||...:..:|....:|:|:..:.....|.|:.....||..||::..:...:
Frog    53 -PQKSNFTDFEG-KTSFGMSVFNLSNAIMGSGILGLAYAMSNTGIILFVFLLISIALLSCYSIHL 115

  Fly   135 LIRGSVLAVERTPGVDFLDYPETVEKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFI 199
            |::.|.:.     |:          :.:|.  ..||......|::..:.:.:...|..:.|...|
Frog   116 LLKCSGVV-----GI----------RAYEQ--LGLRAFGTAGKILAAVIITMHNVGAMSSYLYII 163

  Fly   200 TENLHQVLQ-------------QNG--IVISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVA 249
            ...|..|:|             .||  :::.:|:::::.|      :||.:|.|:...|.|:...
Frog   164 KYELPLVIQTFMGLTSNSGAWYMNGNYLIVIVSILVILPL------ALMKHLGYLGYTSGFSLTC 222

  Fly   250 LLFGLIATLTIAFSDGPMP---SVGDRH-LFTGG-----------------AQLALFFGTALFSY 293
            ::| .:.::...:|..|.|   :|.:.| ::|.|                 :|.|.......|::
Frog   223 MVF-FLCSVIYKYSVIPCPLNSTVAENHTIYTNGQKLEEEDVCTAKLLTVNSQTAYSIPIVAFAF 286

  Fly   294 EGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSI--TLNLVVE 356
            .....:||:...:||..| |....|.|.::|....:::.|....|:.:...|...:  |.|.|..
Frog   287 VCHPEVLPIYTELRRASK-SRMQNVANVSIFAMFIMYLLTAIFGYLTFYGNVESEMLHTYNKVDP 350

  Fly   357 -EVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNN---CT-QKYPITSQVCLRFFMVMMT 416
             :.....|::...:.|.|..|:..|        |::|:..   |. |::.....:.:...:::..
Frog   351 LDKLMLCVRLAVLVAVTLTVPVVLF--------PIRRAIQQLLCPGQEFKWWRHILIAVVLLIAV 407

  Fly   417 FGVALVVPKLNLFISLIGALCSTCLAFVIPVL--IDFV--------TRAQVPKAL-GVWSYIKNI 470
            ..:.:.||.:.....:|||..:..|.|::|.:  |..|        :|.::..|| ....:|..|
Frog   408 NILVIFVPNIKDIFGVIGATSAPSLIFILPSIFYIRIVPNEKEPLRSRPKIQAALFASLGFIFMI 472

  Fly   471 LILTVAVLGIVT 482
            :.|:..::..||
Frog   473 MSLSFIIVDWVT 484

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	87/455 (19%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	87/453 (19%)
slc38a5	NP_001011051.1	SLC5-6-like_sbd	63..480	CDD:320982	86/450 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010