DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and slc38a6

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001008117.2	Gene:	slc38a6 / 493479	XenbaseID:	XB-GENE-1016511	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	458	Identity:	98/458 - (21%)
Similarity:	167/458 - (36%)	Gaps:	102/458 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 PVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSV 140
            |.||....||...|..:|....:|:|:..:.......|:.|.:.||.|:|::..:...:|:|..:
Frog    31 PQRRSSGGTSFGFAVFNLMNAIMGSGILGLSYAMAKTGILGFSALLLIVALLAAYSIHLLLRMCL 95

  Fly   141 LAVERTPGVDFLDYPETVEKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQ 205
            |               |....:|  ...|....|..|::|...:.:...|..:.|...|...|..
Frog    96 L---------------TAVTSYE--DLGLYAFGRSGKVLVACTILIQNVGAMSSYLFIIKSELPA 143

  Fly   206 VLQQ------------NG----IVISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGL 254
            .:..            :|    |:.|:.:|:.:.|||.     :..|.|.|.:|.|..|  .|.:
Frog   144 AIASFLPGAQGEPWYLDGRTLLIITSVCIVLPLALLPK-----IGFLGYTSSLSFFFMV--YFAV 201

  Fly   255 IATL--------------TIAFSDGPMPSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNS 305
            :..:              |:.|...|..|.....||....:.|....|..||:.....:||:...
Frog   202 VIVIKKWNIPCPLPPLNHTVTFLQAPNISECKPKLFDFSKESAFALPTMAFSFLCHTSVLPIYCE 266

  Fly   306 MRRPEKFS----TRFGV-LNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKV 365
            ::.|.|..    ...|: |:..:::.:|||.:..|...|: .|.:.|  ....:.::|....|::
Frog   267 LKSPSKSKMQNVANVGIALSFLIYYISALFGYLTFYDNVK-SELLQG--YSKYLPKDVLIITVRL 328

  Fly   366 IAALGVFLGYPIQFF-----VMIKILWPPLKRSNNCTQKYPITSQVCLRFFMVMMTFGV-----A 420
            ...|.|.|..|:..|     ||:...           .:||.:   .:|..:|.:...:     |
Frog   329 CILLAVLLTVPLIHFPARKAVMMMFF-----------SRYPFS---YIRHILVTLVLNIIIVLLA 379

  Fly   421 LVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTR-----AQVPKALGVWSYIKNILILTVAVLGI 480
            :.||.:.....::|:..||||.||.|.|  |..:     ...|:..|....:         ||||
Frog   380 IYVPDMRSVFGVVGSTTSTCLLFVFPGL--FYVKLGREDCSSPQKFGACGLL---------VLGI 433

  Fly   481 VTG 483
            ..|
Frog   434 CIG 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	95/452 (21%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	95/450 (21%)
slc38a6	NP_001008117.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..36		3/4 (75%)
slc38a6	NP_001008117.2	SLC5-6-like_sbd	37..412	CDD:382020	88/417 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D697331at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.930