DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and CG16700

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_573191.1	Gene:	CG16700 / 32694	FlyBaseID:	FBgn0030816	Length:	468	Species:	Drosophila melanogaster

Alignment Length:	468	Identity:	217/468 - (46%)
Similarity:	310/468 - (66%)	Gaps:	39/468 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 LEKN-----PERFTKNVTEKGADPENG---DPVRRRGHE------TSELEAATHLFKGSVGAGLF 103
            ||||     |.:.|......|.....|   ...:.:.|:      ||.||...|||||::|.|||
  Fly     9 LEKNQTATVPRQETAEGGSTGETAVGGAAAKVTKEQDHDAEYHPPTSYLETIVHLFKGNIGPGLF 73

  Fly   104 AMGDCFKNGGLAGATILLPIIAVMCVHCERMLI---------RG-SVLAVERTPGVDFLDYPETV 158
            ||||.||||||..|.:|..:|||:.:||:.:|:         :| ||.|          ||.:||
  Fly    74 AMGDAFKNGGLLVAPLLTVVIAVVSIHCQHVLVTCSKKMRDLKGDSVCA----------DYAQTV 128

  Fly   159 EKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIVISMSMVMLIT 223
            |:|||:||..||..||.|..:|::|:||||.|||.||||||:.||.|:||...|.:::.:|||:.
  Fly   129 EQCFENGPSKLRGWSRTMGRLVDIFICVTQLGFCCIYFVFISTNLKQILQAYDIDMNVHLVMLLA 193

  Fly   224 LLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRHLFTGGAQLALFFGT 288
            .:|.::.||:||||:::|||:||||.::.||..||..|..|| :|.|.:|.|:|.|:||||||||
  Fly   194 FVPVLLSSLITNLKWLTPVSMFANVCMILGLAITLYYALKDG-LPEVEERALWTNGSQLALFFGT 257

  Fly   289 ALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNL 353
            |:|::|||||::||:|:||:|.:|....||||..||..:.:|:|.|.|.|::|||:|.||:||||
  Fly   258 AIFAFEGIALVMPLKNAMRKPHQFERPLGVLNVGMFLVSVMFMFAGSVGYMKWGEQVGGSLTLNL 322

  Fly   354 VVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNC-TQKYPITSQVCLRFFMVMMTF 417
             .:.:.:|.||::.:.||.||||:||||.|:|:||..|:.  | .:...:..::..|.|||::|.
  Fly   323 -GDTILAQAVKLMVSAGVLLGYPLQFFVAIQIMWPNAKQM--CGIEGRSLLGELGFRTFMVLVTL 384

  Fly   418 GVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVPKALGVWSYIKNILILTVAVLGIVT 482
            .:|.:||.|.||||||||||||.||.|.|.:|:.::|:::.|..|:|..:||::||.:|:||..|
  Fly   385 AIAEMVPALGLFISLIGALCSTALALVFPPVIELISRSELNKGPGIWICVKNLVILVLALLGFFT 449

  Fly   483 GTYQSIVEIVKEF 495
            |:|:|:.:|||.|
  Fly   450 GSYESLKQIVKHF 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	205/423 (48%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	203/414 (49%)
CG16700	NP_573191.1	SLC5-6-like_sbd	53..452	CDD:294310	202/412 (49%)
CG16700	NP_573191.1	SdaC	57..452	CDD:223884	200/408 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453485
Domainoid	1	1.000	157	1.000	Domainoid score	I1306
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1622
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		mtm1178
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
	10	10.010