DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and Slc36a3

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_001019935.1	Gene:	Slc36a3 / 303148	RGDID:	1309092	Length:	477	Species:	Rattus norvegicus

Alignment Length:	486	Identity:	135/486 - (27%)
Similarity:	249/486 - (51%)	Gaps:	51/486 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MGRTLEITGRQNDKSLEKNPERFTKNVTEKGADPENGDPV-------RRRGHETSELEAATHLFK 95
            ||:|..:   :.|...::|....:| .:.||:...:.:..       ||:......::...||.|
  Rat     1 MGKTPLL---REDGRCQRNTFGGSK-ASSKGSSSSSSNNTVSSKKKPRRKADALMFIQIFIHLLK 61

  Fly    96 GSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEK 160
            .::|.|...:....||.||....:.|..|..:.|||..:|:..:.....|... .|::|.||...
  Rat    62 SNIGTGFLGLPLAVKNAGLLVGPVSLLAIGALTVHCMDILLNCACHLTSRLQR-SFVNYEETTMY 125

  Fly   161 CFEHGPRP-LRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQ-----NGIVISMSMV 219
            ..|..|.| ||..|...:.:|...|.|||.|||::||:|:.:||.|::::     |......|:|
  Rat   126 SLETCPSPWLRTHSVWGRYVVSFLLIVTQLGFCSVYFMFMADNLQQIVEEAHFTSNVCQPRQSLV 190

  Fly   220 M---------LITLLPAMI-------PSLMTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMP 268
            |         ::|:||.:|       |.:::....::.::..:::||:|..:..:.   ....:|
  Rat   191 MTSILDTRFYMLTILPFLILLVLVQNPQVLSIFSTLATITTLSSLALIFEYLIQIP---HHSHLP 252

  Fly   269 SVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFT 333
            .|.....|      .||||||:|::||:.::|||::.|:.|::|.   .||...|.|...|:|..
  Rat   253 LVASWKTF------LLFFGTAIFTFEGVGMVLPLKSQMKSPQQFP---AVLYLGMSFVIFLYICL 308

  Fly   334 GFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPLKRSNNCTQ 398
            |.:.|:::|.:...||||||....:: |.||::.::|:|..|.:||.|..:|:.|.:  .:..::
  Rat   309 GTLGYMKFGADTQASITLNLPNCWLY-QSVKLMYSVGIFFTYALQFHVPAEIIVPYV--VSRASE 370

  Fly   399 KYPITSQVCLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQVPKALGV 463
            .:.:...:.:|..:|.:|...|:::|:|:|.|||:|::.|:.||.:||.|::..|  ...:.:..
  Rat   371 NWALFIDLTVRAALVCLTCFSAVLIPRLDLVISLVGSVSSSALALIIPPLLEIAT--FYSENISC 433

  Fly   464 WSYIKNILILTVAVLGIVTGTYQSIVEIVKE 494
            .:..|:|:|..:.:||.|.||||::.|:.::
  Rat   434 TTIAKDIMISILGLLGCVLGTYQALYEMTQQ 464

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	124/428 (29%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	124/425 (29%)
Slc36a3	NP_001019935.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..42		8/44 (18%)
Slc36a3	NP_001019935.1	SLC5-6-like_sbd	52..458	CDD:294310	124/423 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166352580
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.960