DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4991 and avt3

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_593551.1	Gene:	avt3 / 2543612	PomBaseID:	SPAC3H1.09c	Length:	656	Species:	Schizosaccharomyces pombe

Alignment Length:	488	Identity:	119/488 - (24%)
Similarity:	213/488 - (43%)	Gaps:	90/488 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AGEMGRTLEITGRQNDKSLEK-------NPERFTKNVTEKGADPENGDP-VRRRGH-------ET 84
            |||     |::....|:..:.       ||......|      |...:| :.|.|.       ..
pombe   222 AGE-----ELSEEDEDEDTDDFAMPRDVNPSLIHSTV------PSEQEPLISRHGRYKLQTPGNA 275

  Fly    85 SELEAATHLFKGSVGAGLFAMGDCFKNGGLAGATILLPIIAVMCVHCERMLIRGSVLAVERTPGV 149
            |..:|...|.|..||.|:..:...||.|||..::..|.|:.|:...|..:||:..:    :.||
pombe   276 SNGKAVLLLLKSFVGTGVLFLPKAFKLGGLVFSSATLLIVGVLSHICFLLLIQTRM----KVPG- 335

  Fly   150 DFLDYPETVEKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIVI 214
            .|.|...|:     :||.        |:..:...:.|:|.||.:.|..|:...|...::    ||
pombe   336 SFGDIGGTL-----YGPH--------MRFAILASIVVSQIGFSSAYISFVASTLQACVK----VI 383

  Fly   215 S-------MSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLI-----ATLTIAFSDGPM 267
            |       :::.:.|..|..:..||:..:..:|..:|.|:|.:|.|::     ..:|:|     .
pombe   384 STTHREYHLAVFIFIQFLVFVPLSLVRKISKLSATALIADVFILLGILYLYFWDVITLA-----T 443

  Fly   268 PSVGDRHLFTGGAQLALFFGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIF 332
            ..:.|..:| .....:||.|.|:|:||||.||||::..|.:|:....   :|...|...:.|||.
pombe   444 KGIADVAMF-NKTDFSLFIGVAIFTYEGICLILPIQEQMAKPKNLPK---LLTGVMAAISLLFIS 504

  Fly   333 TGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFFVMIKILWPPL-KRSNNC 396
            .|.:||..:|.:|...:.||: .|..|:.:::.:.|:.:.|..|:|.|..|.|:...: .||...
pombe   505 IGLLSYAAFGSKVKTVVILNM-PESTFTVIIQFLYAIAILLSTPLQLFPAIAIIEQGIFTRSGKR 568

  Fly   397 TQKYPITSQVCLRFFMVMMTFGVALVV-----PKLNLFISLIGALCSTCLAFVIPVLIDFVTRAQ 456
            .:|....... ||..:|::    |:::     .:|:||:|::|::|...|.::.|.::.:...|.
pombe   569 NRKIKWRKNY-LRVLIVIL----AILISWAGSSRLDLFVSMVGSVCCIPLIYMYPPMLHYKACAN 628

  Fly   457 --VPKALGVWSYIKNILILTVAVLGIVTGTYQS 487
              :.:.|       :|.:.|:....:...||.:
pombe   629 NWILRTL-------DIFMFTIGAFAMAFTTYMT 654

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	107/433 (25%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	107/424 (25%)
avt3	NP_593551.1	SdaC	270..656	CDD:223884	107/429 (25%)
avt3	NP_593551.1	Aa_trans	273..656	CDD:279788	107/426 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	126	1.000	Domainoid score	I1377
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	126	1.000	Inparanoid score	I1449
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	1	1.000	-	-		otm47069
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
TreeFam	0	0.000	Not matched by this tool.
	7	6.960