DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4991 and Slc38a7

DIOPT Version :9

Sequence 1:	NP_001259638.1	Gene:	CG4991 / 32695	FlyBaseID:	FBgn0030817	Length:	496	Species:	Drosophila melanogaster
Sequence 2:	NP_766346.1	Gene:	Slc38a7 / 234595	MGIID:	2679005	Length:	463	Species:	Mus musculus

Alignment Length:	501	Identity:	119/501 - (23%)
Similarity:	195/501 - (38%)	Gaps:	119/501 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    35 AGEMGRTLEITGRQNDKSLEKNPERFTKNVTEKGADPENGDPVRRRGHETSELEAATHLFKGSVG 99
            |||..|.|:      ...::..|:      :|..|.|  |||   ....||.|.|...:....:|
Mouse    19 AGERARLLQ------SPCVDVVPK------SEGEASP--GDP---DSGTTSTLGAVFIVVNACLG 66

  Fly   100 AGLFAMGDCFKNGGLAGATILLP------IIA--VMCVHCERMLIRGSVLAVERTPGVDFLDYPE 156
            |||......|...|...|.|.|.      ||:  |:..:|       |..:.|||       |.|
Mouse    67 AGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYC-------SQASNERT-------YQE 117

  Fly   157 TV-EKCFEHGPRPLRKMSRVMKLIVEMFLCVTQFGFCAIYFVFITENLHQVLQQNGIV------- 213
            .| ..|           .::..::.|:.:.|..||.|..:.:.|.:      ||:.|:
Mouse   118 VVWAVC-----------GKLTGVLCEVAIAVYTFGTCIAFLIIIGD------QQDKIIAVMSKEP 165

  Fly   214 -------------ISMSMVMLITLLPAMIPSLMTNLKYISPVSLFANVALLFGLIATLTIAF--S 263
                         .::|:...:.:||..||..:...||.|    |.:|...:.:.|.:.|.:  .
Mouse   166 DGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYAS----FLSVVGTWYVTAIIIIKYIWP 226

  Fly   264 DGPMPSVGDRHLFTGGAQ-LALF--FGTALFSYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFF 325
            |..| ..||  :.|..|. :|:|  ..|..|.::.....:|:.||||:|| ..|..||:.:.|..
Mouse   227 DKEM-RPGD--ILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPE-VKTWGGVVTAAMVI 287

  Fly   326 TTALFIFTGFVSYVRWGEEVAGSITLNLVVEEVFSQVVKVIAALGVFLGYPIQFF---VMIKILW 387
            ..|:::.||...::.:|..|...:..:...|:|...|.:....|.|...|||..|   .:::.||
Mouse   288 ALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLW 352

  Fly   388 PPLKRSNNCTQKYPITSQV----------CLRFFMVMMTFGVALVVPKLNLFISLIGALCSTCLA 442
            ...|       ..|:...|          .|.:|  ::|..:||.:|.:...||:||.| :.|..
Mouse   353 LRYK-------GMPVEEDVGRERRRRVLQTLVWF--LLTLLLALFIPDIGKVISVIGGL-AACFI 407

  Fly   443 FVIPVLIDF---VTRAQVPKALGVWSYIK-NILILTVA--VLGIVT 482
            |:.|.|...   ::..:..|....|:.:. .:|::|:.  :.|..|
Mouse   408 FIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFGQTT 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	107/454 (24%)
CG4991	NP_001259638.1	SdaC	84..488	CDD:223884	107/452 (24%)
Slc38a7	NP_766346.1	SLC5-6-like_sbd	49..458	CDD:382020	107/454 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167848968
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4217
OMA	1	1.010	-	-		QHG54358
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.800