Protein Alignment CG4991 and Slc36a1

DIOPT Version :10

• Sequence 1: NP_001259638.1
• Gene: CG4991 / 32695
• FlyBaseID: FBgn0030817
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: NP_694779.3
• Gene: Slc36a1 / 215335
• MGIID: 2445299
• Length: 475
• Species: Mus musculus
• Alignment Length: 749
• Identity: 143/749 - (19%)
• Similarity: 252/749 - (33%)
• Gaps: 218/749 - (29%)

  Fly   936 PACETPYVLVSSDNDDSVRFW----RCAKATDP---------VSPNKFEWREWNMISDNHPSELG 987
            |.||.  |..:.......:.|    |....|.|         .||.|...:: ..:.:|.||.|.
Mouse    85 PYCEA--VFATKVRLQKHKLWNHPERVTMETKPDPKPEPKQQKSPMKGNAKK-RPVENNPPSPLF 146

  Fly   988 VEGSIVKVNAAHSGRIACAYQKPNTTTDNNIIIEVAVFECESSGG---VEWFREDSFRIQQNHFF 1049
            .:....:..:..|....||.|:|:.....|..::..  ..||.||   ..:..||..|::.....
Mouse   147 FKVKKTQEASQPSQNGDCAPQRPDRRQQQNSSVDTG--GSESEGGSLPPPFPEEDPERMKHRRKQ 209

  Fly  1050 EFSKPHFTGSQ-SKRHSGDQEHLHLLQQRINAGKPTKPSYELIRAMENASSSVTDIAQMKLENMV 1113
            :..| .|||.| |...:...:.::.:::::.||:           |:.|
Mouse   210 KTPK-KFTGEQPSISGTFGLKGMNKVEEKLKAGR-----------MKRA---------------- 246

  Fly  1114 RLDWVSTEDGTHMLTVGMGTKVYIYAQIGQDPAQQNVTLMRESETSMRRPSIRKASSLLPNIQPD 1178
                    :||....              :.|.:|          |.:.|:.::|||:.|   .:
Mouse   247 --------EGTQFSE--------------ESPRKQ----------STQTPNRKEASSVPP---AE 276

  Fly  1179 SRFTSW-------VC--CRVLNLDTADGLPPIPTALSWVRDGILIVGMQSEMRVYNQWNFKTVQE 1234
            :::.|.       ||  |.|:...|..||.........:||.:.....|.:.|.....|:..:.:
Mouse   277 AQWQSTISERGEVVCPTCSVVTRKTVHGLKKHMEICQKLRDALKCQQCQKQFRSKAALNYHNMAD 341

  Fly  1235 KTKSSNPAANPNIVSLTVSTSHSMLDQLTRKKEALVSSRSRVFLEFVSTMNKAHPKENESQMVLN 1299
            ..|   |:|:.|:                                       :..::.|.:.:..
Mouse   342 HIK---PSASENV---------------------------------------SGEEQEERERLHC 364

  Fly  1300 ILKSEGVFE------TARMCSPILPQYHPKQLIVLLNAGKKRRVKAILNHVLSSLKQKKGAAHNP 1358
            |||..|..:      :|...|.:..|||.|:....| .|.::.| .:..|...:.:.|.|..::
Mouse   365 ILKQMGRIKCPNEGCSAHFSSLMSYQYHQKRCASEL-PGTQKPV-FLCQHCGKTYRSKTGRDYH- 426

  Fly  1359 LSRAASIKRMSTVDREDSTNATPADARIDDDSMDYDEIDDIPLLPLYALMKVDFDSDVVVEKSEE 1423
             .|...|....|...||  |....|...::|..|.:|.|:          :...:.:.|::||.|
Mouse   427 -QRTEHIITTLTTYPED--NKDEEDVLEEEDDDDEEEEDE----------EEQEEEEPVLKKSIE 478

  Fly  1424 LMAKNTDEYDDLFDDGLDKDGDIDAILRDNESMYSGRSRHMSGGSDMGRNENQVSAIF------- 1481
            ...::..|..:...:..::.|:::.:| |.|...|||.|         |...|| |:|
Mouse   479 QERQSEGEQVEKMQERKEEKGEVEDLL-DLERTPSGRVR---------RRSAQV-AVFHLQEIAE 532

  Fly  1482 --TAKDYRKLTEL----------LTHTHLPGLSSVDQMHLLAIADTLSHFASDAKDK--VEQANA 1532
              .|||:.....:          |.:|. |||.:..       .:|:..:.::.|:|  :...|.
Mouse   533 DELAKDWGTKQRIKDDLVPDIKRLNYTR-PGLPNFS-------PETVDSWKNEVKEKGFICCPNC 589

  Fly  1533 AMKPVVQSVLG-------DNTAGG----YATAAAGVETVDECGLRYLMAMKQHEYLMVCLPMKQR 1586
            ..:.:..||.|       .|..||    |.......|...|.|::|.: .|.|..........:.
Mouse   590 NCEAIYSSVSGLKAHLASCNKGGGDVGKYTCLLCQKEFNSESGVKYHI-NKTHSQNWFRASANEM 653

  Fly  1587 MELKKSGLSASNIIWAQHSETETELLNAVPGMHR 1620
            ...||....::.:        :.::.|||.|..|
Mouse   654 ANNKKKEPESNGL--------QKDMKNAVAGKRR 679

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:444915
Slc36a1	NP_694779.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..32
		SLC5-6-like_sbd	47..452	CDD:444915	89/482 (18%)