Protein Alignment CG4991 and SLC36A1

DIOPT Version :9

• Sequence 1: NP_001259638.1
• Gene: CG4991 / 32695
• FlyBaseID: FBgn0030817
• Length: 496
• Species: Drosophila melanogaster
• Sequence 2: XP_011535882.1
• Gene: SLC36A1 / 206358
• HGNCID: 18761
• Length: 482
• Species: Homo sapiens
• Alignment Length: 467
• Identity: 145/467 - (31%)
• Similarity: 247/467 - (52%)
• Gaps: 46/467 - (9%)

  Fly    50 DKSLEKNPERFTKNVTEKGADPENGDPVRRRGHETSELEAATHLFKGSVGAGLFAMGDCFKNGGL 114
            |.|.|::|.....|::..|:....|     :.:.|:..:...||.||::|.||..:....||.|:
Human    24 DVSPEESPSEGLNNLSSPGSYQRFG-----QSNSTTWFQTLIHLLKGNIGTGLLGLPLAVKNAGI 83

  Fly   115 AGATILLPIIAVMCVHCERMLIRGSVLAVERTPGVDFLDYPETVEKCFEHGPRP-LRKMSRVMKL 178
            ....|.|.||.::.|||..:|::.:.....|. ...|:||.:||....|..|.. ||..:...:.
Human    84 VMGPISLLIIGIVAVHCMGILVKCAHHFCRRL-NKSFVDYGDTVMYGLESSPCSWLRNHAHWGRR 147

  Fly   179 IVEMFLCVTQFGFCAIYFVFITENLHQVLQ-QNG----------IVISMSM---VMLITLLPAMI 229
            :|:.||.|||.|||.:||||:.:|..||:: .||          ::::.:|   :.:::.||.::
Human   148 VVDFFLIVTQLGFCCVYFVFLADNFKQVIEAANGTTNNCHNNETVILTPTMDSRLYMLSFLPFLV 212

  Fly   230 PSL-MTNLKYISPVSLFANVALLFGLIATLTIAFSDGPMPSVGDRH--LFTGGAQLALFFGTALF 291
            ..: :.||:.:|..||.||:.:|..|:..........|.||    |  |........||||||:|
Human   213 LLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIPDPS----HLPLVAPWKTYPLFFGTAIF 273

  Fly   292 SYEGIALILPLRNSMRRPEKFSTRFGVLNSTMFFTTALFIFTGFVSYVRWGEEVAGSITLNLVVE 356
            |:|||.::|||.|.|:.|.||..   :|...|...|.|:|..|.:.|:::|..:.|||||||...
Human   274 SFEGIGMVLPLENKMKDPRKFPL---ILYLGMVIVTILYISLGCLGYLQFGANIQGSITLNLPNC 335

  Fly   357 EVFSQVVKVIAALGVFLGYPIQFFVMIKILWP--PLKRSNNCTQKYPITSQVCLRFFMVMMTFGV 419
            .:: |.||::.::|:|..|.:||:|..:|:.|  ..:...:|    .:...:.:|..:|.:|..:
Human   336 WLY-QSVKLLYSIGIFFTYALQFYVPAEIIIPFFVSRAPEHC----ELVVDLFVRTVLVCLTCIL 395

  Fly   420 ALVVPKLNLFISLIGALCSTCLAFVIPVLID---FVTRAQVPKALGVWSYIKNILILTVAVLGIV 481
            |:::|:|:|.|||:|::.|:.||.:||.|::   |.:....|..:     .|:.||..:..:|.|
Human   396 AILIPRLDLVISLVGSVSSSALALIIPPLLEVTTFYSEGMSPLTI-----FKDALISILGFVGFV 455

  Fly   482 TGTYQSIVEIVK 493
            .|||:::.|:::
Human   456 VGTYEALYELIQ 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4991	NP_001259638.1	SLC5-6-like_sbd	82..489	CDD:294310	137/429 (32%)
		SdaC	84..488	CDD:223884	137/426 (32%)
SLC36A1	XP_011535882.1	SLC5-6-like_sbd	53..459	CDD:294310	135/423 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165158557
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54358
OrthoDB	1	1.010	-	-		D284074at33208
OrthoFinder	1	1.000	-	-		FOG0000138
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X121
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.960